Existence of a molecular ruler in proteasomes suggested by analysis of degradation products

THE UBIQUITIN SYSTEM FOR PROTEIN DEGRADATION

1992 • 1,402 citations

Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination

1992 • 780 citations

The determination of protein, oligonucleotide and peptide molecular weights by ion‐spray mass spectrometry

1988 • 592 citations

Interpreting mass spectra of multiply charged ions

1989 • 579 citations

Proteolysis, proteasomes and antigen presentation

1992 • 576 citations

γ-Interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

1993 • 572 citations

The multicatalytic and 26 S proteases.

1993 • 476 citations

MHC-linked LMP gene products specifically alter peptidase activities of the proteasome

1993 • 453 citations

A proteasome-related gene between the two ABC transporter loci in the class II region of the human MHC

1991 • 427 citations

Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle

1992 • 414 citations

Proteasomes: multicatalytic proteinase complexes

1993 • 395 citations

Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids

1993 • 323 citations

Structural and serological similarity of MHC-linked LMP and proteasome (multicatalytic proteinase) complexes

1991 • 310 citations

The multicatalytic proteinase (prosome) is ubiquitous from eukaryotes to archaebacteria

1989 • 277 citations

Structural Features of the 26 S Proteasome Complex

1993 • 255 citations

Primary structure of the Thermoplasma proteasome and its implications for the structure, function, and evolution of the multicatalytic proteinase

1992 • 235 citations

Subunit stoichiometry and three-dimensional arrangement in proteasomes from Thermoplasma acidophilum.

1992 • 180 citations

Die Synthese verschiedener Carbonsäuren durch den Multienzymkomplex der Fettsäuresynthese aus Hefe und die Erklärung ihrer Bildung

1969 • 154 citations

Electron microscopy and image analysis of the multicatalytic proteinase

1988 • 150 citations

In vivo function of the proteasome in the ubiquitin pathway.

1992 • 144 citations

Proteasomes: protein and gene structures.

1992 • 108 citations

Stress‐induced proteolysis in yeast

1992 • 103 citations

Degradation of oxidized insulin B chain by the multiproteinase complex macropain (proteasome)

1991 • 99 citations

The three‐dimensional structure of proteasomes from Thermoplasma acidophilum as determined by electron microscopy using random conical tilting

1991 • 92 citations

Expression of functional Thermoplasma acidophilum proteasomes in Escherichia coli

1992 • 89 citations

Proteasomes from Dictyostelium discoideum: Characterization of Structure and Function

1993 • 74 citations

Identification of three high molecular mass cysteine proteinases from rat skeletal muscle

1983 • 57 citations

A controlled breakdown: Antigen processing and the turnover of viral proteins

1992 • 54 citations

Thermoplasma acidophilum proteasomes degrade partially unfolded and ubiquitin‐associated proteins

1993 • 52 citations

The ATP-independent pathway in red blood cells that degrades oxidant-damaged hemoglobin

1992 • 35 citations

Preliminary X-ray Crystallographic Study of the Proteasome from Thermoplasma acidophilum

1993 • 27 citations