Proteasome: a complex protease with a new fold and a distinct mechanism
Data up to Jan 2025
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Abstract
References (14)
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
1994 • 2,480 citations
Crystal Structure of the 20 S Proteasome from the Archaeon T. acidophilum at 3.4 Å Resolution
1995 • 1,513 citations
The crystal structure of the bacterial chaperonln GroEL at 2.8 Å
1994 • 1,322 citations
Proteolysis, proteasomes and antigen presentation
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The multicatalytic proteinase complex, a major extralysosomal proteolytic system
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1993 • 395 citations
Crystal structure of Escherichia coli L-asparaginase, an enzyme used in cancer therapy.
1993 • 294 citations
Conformational constraints in protein degradation by the 20S proteasome
1995 • 202 citations
A serine and a lysine residue implicated in the catalytic mechanism of the Escherichia coli leader peptidase.
1993 • 123 citations
Proteasomes: protein and gene structures.
1992 • 108 citations
The three‐dimensional structure of proteasomes from Thermoplasma acidophilum as determined by electron microscopy using random conical tilting
1991 • 92 citations
Structure of a Phosphonate-inhibited β-Lactamase
1993 • 73 citations
Structural Characterization of Pseudomonas 7A Glutaminase-Asparaginase
1994 • 71 citations
Preliminary X-ray Crystallographic Study of the Proteasome from Thermoplasma acidophilum
1993 • 27 citations