γ-Aminobutyric Acid Metabolism and Biochemistry of Synaptic Transmission

Handbook of Psychopharmacology

1988 • 2,778 citations

Chemical Nature of Synaptic Transmission in Vertebrates

1974 • 1,613 citations

Handbook of Neurochemistry

1972 • 1,374 citations

Fine structural localization of glutamine synthetase in astrocytes of rat brain

1979 • 1,318 citations

Glutamine Synthetase: Glial Localization in Brain

1977 • 1,170 citations

Psychopharmacology : a generation of progress

1978 • 1,168 citations

Basic Mechanisms of the Epilepsies.

1970 • 1,131 citations

GABA in nervous system function

1977 • 1,087 citations

GABA neurons are the major cell type of the nucleus reticularis thalami

1980 • 667 citations

Immunocytochemical localization of glutamic acid decarboxylase in neuronal somata following colchicine inhibition of axonal transport

1978 • 633 citations

Functional interactions between neurons and astrocytes I. Turnover and metabolism of putative amino acid transmitters

1979 • 622 citations

Uptake and metabolism of γ-aminobutyric acid by neurones and glial cells

1975 • 564 citations

Aspinous and sparsely-spinous stellate neurons in the visual cortex of rats contain glutamic acid decarboxylase

1978 • 549 citations

SUBCELLULAR DISTRIBUTION OF THE ENZYMES OF THE GLUTAMIC ACID, GLUTAMINE AND γ‐AMINOBUTYRIC ACID CYCLES IN RAT BRAIN*

1965 • 539 citations

GABA in nervous system function

1976 • 529 citations

Epilepsy and γ-Aminobutyric Acid-Mediated Inhibition

1975 • 491 citations

γ‐VINYL GABA (4‐amino‐hex‐5‐enoic acid), A NEW SELECTIVE IRREVERSIBLE INHIBITOR OF GABA‐T: EFFECTS ON BRAIN GABA METABOLISM IN MICE¹

1977 • 472 citations

Glial Cell Function: Uptake of Transmitter Substances

1971 • 460 citations

Inhibition in the nervous system and gamma-aminobutyric acid

1961 • 412 citations

The GABA Neurons and their axon terminals in rat corpus striatum as demonstrated by GAD immunocytochemistry

1979 • 408 citations

PYRIDOXINE DEPENDENCY: REPORT OF A CASE OF INTRACTABLE CONVULSIONS IN AN INFANT CONTROLLED BY PYRIDOXINE

1954 • 405 citations

Tissue culture in neurobiology

1980 • 401 citations

GLUTAMINE—A MAJOR SUBSTRATE FOR NERVE ENDINGS

1978 • 380 citations

4‐Amino‐hex‐5‐enoic Acid, a Selective Catalytic Inhibitor of 4‐Aminobutyric‐Acid Aminotransferase in Mammalian Brain

1977 • 375 citations

GABAergic terminals are presynaptic to primary afferent terminals in the substantia gelatinosa of the rat spinal cord

1978 • 344 citations

UPTAKE AND METABOLISM OF GLUTAMATE IN ASTROCYTES CULTURED FROM DISSOCIATED MOUSE BRAIN HEMISPHERES

1977 • 343 citations

INHIBITION OF GABA UPTAKE IN RAT BRAIN SLICES BY NIPECOTIC ACID, VARIOUS ISOXAZOLES AND RELATED COMPOUNDS

1975 • 329 citations

Distribution of putative neurotransmitters in the neocortex

1979 • 316 citations

The operation of the γ-aminobutyrate bypath of the tricarboxylic acid cycle in brain tissue in vitro

1970 • 306 citations

Metabolic Compartmentation and Neurotransmission

1975 • 301 citations

AMINO ACID AND PROTEIN METABOLISM‐VI CEREBRAL COMPARTMENTS OF GLUTAMIC ACID METABOLISM

1961 • 295 citations

Selective uptake of [3H]β-alanine by glia: Association with the glial uptake system for GABA

1975 • 288 citations

On the Role of Glial Cells in the Mammalian Nervous System

1974 • 277 citations

CONVULSIVE SEIZURES IN INFANTS WITH PYRIDOXINE-DEFICIENT DIET

1954 • 260 citations

Active transport of γ-aminobutyric acid by membrane vesicles isolated from rat brain

1978 • 253 citations

Amino acid pools

1962 • 252 citations

The distribution of glutamate decarboxylase and aspartate transaminase in subcellular fractions of rat and guinea-pig brain

1968 • 249 citations

The characterisation of [3H]GABA uptake into the satellite glial cells of rat sensory ganglia

1974 • 246 citations

Glutamine: Metabolism, Enzymology, and Regulation

1980 • 220 citations

THE EFFECT OF 4‐AMINO HEX‐5‐YNOIC ACID (γ‐ACETYLENIC GABA, γ‐ETHYNYL GABA) A CATALYTIC INHIBITOR OF GABA TRANSAMINASE, ON BRAIN GABA METABOLISM IN VIVO

1977 • 216 citations

Neuropharmacology of Amino Acid Inhibitory Transmitters

1978 • 212 citations

Compartmentation of Amino Acid Metabolism

1969 • 209 citations

Effects of drugs on γ-aminobutyric acid receptors, uptake, release and synthesis in vitro

1978 • 205 citations

On glutaminase activity in mammalian synaptosomes

1976 • 204 citations

Audiogenic seizure protection by elevated brain GABA concentration in mice: Effects of γ-acetylenic GABA and γ-vinyl GABA, two irreversible GABA-T inhibitors

1977 • 203 citations

INHIBITION OF THE UPTAKE OF GABA AND RELATED AMINO ACIDS IN RAT BRAIN SLICES BY THE OPTICAL ISOMERS OF NIPECOTIC ACID

1976 • 202 citations

RELEASE OF [³H]GAMMA-AMINOBUTYRIC ACID FROM GLIAL CELLS IN RAT DORSAL ROOT GANGLIA.

1974 • 194 citations

Uptake and metabolism of GABA in astrocytes cultured from dissociated mouse brain hemispheres

1977 • 186 citations

PROPERTIES OF BRAIN <scp>l</scp>‐GLUTAMATE DECARBOXYLASE: INHIBITION STUDIES¹

1974 • 186 citations

Stimulus‐secretion coupling processes in brain: analysis of noradrenaline and gamma‐aminobutyric acid release.

1976 • 183 citations

BACLOFEN: EFFECTS ON AMINO ACID RELEASE AND METABOLISM IN SLICES OF GUINEA PIG CEREBRAL CORTEX

1979 • 180 citations

SYNAPTOSOMAL TRANSPORT: A CHLORIDE DEPENDENCE FOR CHOLINE, GABA, GLYCINE AND SEVERAL OTHER COMPOUNDS

1978 • 178 citations

Active-site-directed irreversible inhibition of rat brain 4-aminobutyrate aminotransferase by ethanolamine O-sulphate in vitro and in vivo

1972 • 178 citations

Anticonvulsant action of ethanolamine-O-sulphate and di-n-propylacetate and the metabolism of γ-aminobutyric acid (GABA) in mice with audiogenic seizures

1976 • 175 citations

Betel nut constituents as inhibitors of γ-aminobutyric acid uptake

1975 • 175 citations

Seizure Protection and Increased Nerve-Terminal GABA: Delayed Effects of GABA Transaminase Inhibition

1980 • 175 citations

Inhibitors of GABA metabolism

1979 • 170 citations

Demonstration of central γ-aminobutyrate-containing nerve terminals by means of antibodies against glutamate decar☐ylase

1981 • 169 citations

Exchange of neurotransmitter amino acid at nerve endings can simulate high affinity uptake

1974 • 168 citations

Effect of Inhibitors of GABA Transaminase on the Synthesis, Binding, Uptake and Metabolism of GABA

1980 • 167 citations

Selective inhibition of neuronal GABA uptake by cis-1,3-aminocyclohexane carboxylic acid

1976 • 163 citations

γ-Aminobutyric Acid Uptake by Sympathetic Ganglia

1972 • 162 citations

The gamma-aminobutyric acid system in rabbit retina: localization by immunocytochemistry and autoradiography.

1979 • 161 citations

Immunocytochemical localisation of L-glutamic acid decarboxylase in the goldfish retina

1979 • 161 citations

Gabaergic nerve terminals decrease in the substantia nigra following hemitransections of the striatonigral and pallidonigral pathways

1980 • 159 citations

Glutamine as precursor for the GABA and glutamate trasmitter pools

1978 • 158 citations

Potassium-induced release of amino acids from cerebral cortex and spinal cord slices of the rat

1974 • 156 citations

Potassium-stimulated γ-aminobutyric acid release from neurons and glia

1977 • 154 citations

GABAergic amacrine cells in rat retina: Immunocytochemical identification and synaptic connectivity

1981 • 151 citations

Criteria for the identification of central neurotransmitters, and their application to studies with some nerve tissue preparations in vitro

1979 • 148 citations

EFFECTS OF ELEVATED [K⁺]₀ ON THE RELEASE OF NEUROTRANSMITTERS FROM CORTICAL SYNAPTOSOMES: EFFLUX OR SECRETION?

1978 • 143 citations

Mechanism of the irreversible inhibition of γ-aminobutyric acid-α-ketoglutaric acid transaminase by the neurotoxin gabaculine

1977 • 141 citations

Purification and characterization of the 4-aminobutyrate-2-ketoglutarate transaminase from mouse brain

1973 • 141 citations

The role of γ-aminobutyric acid in the mechanism of seizures

1975 • 140 citations

ADAPTIVE MECHANISMS OF THE NORADRENERGIC CYCLIC AMP GENERATING SYSTEM IN THE LIMBIC FOREBRAIN OF THE RAT: ADAPTATION TO PERSISTENT CHANGES IN THE AVAILABILITY OF NOREPINEPHRINE (NE)^1,2

1976 • 136 citations

High affinity transport of taurine and beta-alanine and low affinity transport of gamma-aminobutyric acid by a single transport system in cultured glioma cells.

1979 • 133 citations

THE MECHANISM OF ACTION OF β‐BUNGAROTOXIN

1975 • 130 citations

Purification and Some Properties of <scp>l</scp>‐Glutamate Decarboxylase from Human Brain

1978 • 130 citations

Influence of inhibitors of the high affinity GABA uptake on seizure thresholds in mice

1979 • 128 citations

ORNITHINE AND GLUTAMIC ACID DECARBOXYLASE ACTIVITIES IN THE DEVELOPING CHICK RETINA

1976 • 126 citations

Amino acids as chemical transmitters

1980 • 120 citations

GABA—Biochemistry and CNS Functions

1979 • 119 citations

RELEASE AND EXCHANGE STUDIES RELATING TO THE SYNAPTOSOMAL UPTAKE OF GABA

1975 • 119 citations

The pharmacology of GABA-transaminase inhibitors

1981 • 116 citations

The release of endogenous amino acids from the rat visual cortex.

1976 • 116 citations

Studies on the Mechanism of Action of Avermectin B₁a: Stimulation of Release of γ‐Aminobutyric Acid from Brain Synaptosomes

1980 • 115 citations

Monoamine and GABA metabolism and the anticonvulsant action of DI-n-propylacetate and ethanolamine-O-sulphate

1977 • 113 citations

Amino Acids as Central Neurotransmitters

1975 • 112 citations

Ontogeny of Neurochemical Markers for Noradrenergic, GABAergic and Cholinergic Neurons in Neocortex Lesioned with Methylazoxymethanol Acetate

1980 • 111 citations

ON THE SITE OF ORIGIN OF TRANSMITTER AMINO ACIDS RELEASED BY DEPOLARIZATION OF NERVE TERMINALS IN VITRO

1977 • 111 citations

EFFECTS OF THE ANTICONVULSANT SODIUM VALPROATE ON γ‐AMINOBUTYRATE AND ALDEHYDE METABOLISM IN OX BRAIN

1978 • 109 citations

Effect of n‐dipropylacetate on amino acid concentrations in mouse brain: correlations with anti‐convulsant activity

1978 • 108 citations

3-Mercaptopropionic acid: Convulsant properties, effects on enzymes of the γ-aminobutyrate system in mouse brain and antagonism by certain anticonvulsant drugs, aminooxyacetic acid and gabaculine

1979 • 108 citations

Neurochemical correlates of synaptically active amino acids

1974 • 107 citations

Metabolic inhibitors and subcellular distribution of GABA

1979 • 105 citations

COMPETITIVE INHIBITION OF GABA UPTAKE IN RAT BRAIN SLICES BY SOME GABA ANALOGUES OF RESTRICTED CONFORMATION

1972 • 105 citations

NEURONAL AND GLIAL SYSTEMS FOR γ‐AMINOBUTYRIC ACID METABOLISM

1975 • 104 citations

Uptake of neurotransmitters by clonal lines of astrocytoma and neuroblastoma in culture. I. Transport of γ-aminobutyric acid

1974 • 104 citations

Effects of the Areca nut constituents arecaidine and guvacine on the action of GABA in the cat central nervous system

1977 • 103 citations

A Model of Glutamate Metabolism in Brain: A Biochemical Analysis of a Heterogeneous Structure

1975 • 100 citations

STUDIES ON THE REGULATION OF GABA SYNTHESIS: SUBSTRATE‐PROMOTED DISSOCIATION OF PYRIDOXAL‐5′‐PHOSPHATE FROM GAD

1978 • 100 citations

The uptake and release of putative amino acid neurotransmitters

1979 • 99 citations

Influence of membrane potential on the sodium-dependent uptake of gamma-aminobutyric acid by presynaptic nerve terminals: Experimental observations and theoretical considerations

1976 • 98 citations

Effect of Inhibitors of GABA Aminotransferase on the Metabolism of GABA in Brain Tissue and Synaptosomal Fractions

1981 • 98 citations

Transport Phenomena in the Nervous System

1976 • 95 citations

NEURONAL AND GLIAL SYSTEMS FOR γ‐AMINOBUTYRIC ACID TRANSPORT

1975 • 94 citations

Post-mortem changes implicate adenine nucleotides and pyridoxal-5′-phosphate in regulation of brain glutamate decarboxylase

1977 • 94 citations

Kinetic and spectral properties of rabbit brain 4-aminobutyrate aminotransferase

1976 • 93 citations

Convulsant and anticonvulsant actions in DBA/2 mice of compounds blocking the reuptake of GABA

1979 • 92 citations

KINETICS OF IN VIVO CONVERSION OF γ‐[³H]AMINOBUTYRIC ACID TO γ‐[³H]HYDROXYBUTYRIC ACID BY RAT BRAIN^1,2

1977 • 91 citations

CALCIUM‐DEPENDENT RELEASE OF EXOGENOUSLY LOADED γ‐AMINO‐[U‐¹⁴C]BUTYRATE FROM SYNAPTOSOMES: TIME COURSE OF STIMULATION BY POTASSIUM, VERATRIDINE, AND THE CALCIUM IONOPHORE, A23187

1976 • 90 citations

SODIUM‐DEPENDENT EFFLUX AND EXCHANGE OF GABA IN SYNAPTOSOMES

1974 • 90 citations

Differential Labeling of Glial Cells and GABA-inhibitory Interneurons and Nerve Terminals following the Microinjection of [ -3H]Alanine, [3H]DABA and [3H]GABA into Single Folia of the Cerebellum

1976 • 89 citations

Changes in Regional Brain Levels of Amino Acid Putative Neurotransmitters After Prolonged Treatment with t he Anticonvulsant Drugs Diphenylhydantoin, Phenobarbitone, Sodium Valproate, Ethosuximide, and Sulthiame in the Rat

1981 • 89 citations

Compartmentation of amino acid metabolism in the rat dorsal root ganglion; a metabolic and autoradiographic study

1975 • 88 citations

The in vivo inhibition of gaba-transaminase by gabaculine

1977 • 88 citations

Pentobarbital depression of stimulus-secretion coupling in brain— Selective inhibition of depolarization-induced calcium-dependent release

1977 • 87 citations

Sodium‐Dependent Efflux of [³H]GABA from Synaptosomes Probably Related to Mitochondrial Calcium Mobilization

1980 • 87 citations

GABA-TRANSAMINASES OF HUMAN BRAIN AND PERIPHERAL TISSUES?KINETIC AND MOLECULAR PROPERTIES

1978 • 86 citations

STABILITY OF SYNAPTOSOMAL GABA LEVELS AND THEIR USE IN DETERMINING THE IN VIVO EFFECTS OF DRUGS: CONVULSANT AGENTS

1979 • 85 citations

Dissociation between drug-induced increases in nerve terminal and non-nerve terminal pools of GABA in vivo

1979 • 83 citations

PYRIDOXINE DEFICIENCY IN THE NEONATAL RAT

1969 • 83 citations

The emergence, localization and maturation of neurotransmitter systems during development of the retina in Xenopus laevis. I. γ‐aminobutyric acid

1979 • 81 citations

Evidence for net uptake of GABA into mouse astrocytes in primary cultures?Its sodium dependence and potassium independence

1978 • 80 citations

ON THE MECHANISM BY WHICH VERATRIDINE CAUSES A CALCIUM‐INDEPENDENT RELEASE OF γ‐AMINOBUTYRIC ACID FROM BRAIN SLICES

1981 • 80 citations

GLUTAMINE UPTAKE AND METABOLISM BY THE ISOLATED TOAD BRAIN: EVIDENCE PERTAINING TO ITS PROPOSED ROLE AS A TRANSMITTER PRECURSOR

1977 • 78 citations

FACTORS INFLUENCING THE EFFLUX OF [³H]GAMMAAMINOBUTYRIC ACID FROM SATELLITE GLIAL CELLS IN RAT SENSORY GANGLIA

1975 • 78 citations

Glutamine and glutamate as precursors of the releasable pool of gaba in brain cortex slices

1978 • 77 citations

Cis-3-aminocyclohexanecar☐ylic acid: a substrate for the neuronal GABA transport system

1977 • 76 citations

Differential effects of veratridine and potassium depolarization on neuronal and glial gaba release

1979 • 76 citations

Purification and Studies on Some Properties of the 4‐Aminobutyrate: 2‐Oxoglutarate Transaminase from Rat Brain

1975 • 76 citations

RELATIONSHIP BETWEEN Ca²⁺‐DEPENDENT AND INDEPENDENT RELEASE OF [³H]GABA EVOKED BY HIGH K⁺, VERATRIDINE OR ELECTRICAL STIMULATION FROM RAT CORTICAL SLICES

1979 • 74 citations

Application of principles of steady-state kinetics to the estimation of gamma-aminobutyric acid turnover rate in nuclei of rat brain.

1977 • 73 citations

EFFECTS OF TETRODOTOXIN, CALCIUM AND MAGNESIUM ON THE RELEASE OF AMINO ACIDS FROM SLICES OF GUINEA‐PIG CEREBRAL CORTEX

1978 • 71 citations

NEURONAL‐GLIAL CONTRIBUTIONS TO TRANSMITTER AMINO ACID METABOLISM: STUDIES WITH KAINIC ACID‐INDUCED LESIONS OF RAT STRIATUM

1979 • 70 citations

Amino acid release from isolated rat dorsal root ganglia

1974 • 70 citations

Biochemistry and neurology

1977 • 69 citations

Comparative study of the release of glutamate and GABA, newly synthesized from glutamine, in various regions of the central nervous system

1980 • 68 citations

Inhibition by ruthenium red of the calcium-dependent release of [3H]GABA in synaptosomal fractions

1977 • 68 citations

Release of endogenous amino acid neurotransmitter candidates from rat olfactory cortex slices: Possible regulatory mechanisms and the effects of pentobarbitone

1980 • 68 citations

Postnatal development of GABA‐ergic neurons in the rabbit retina

1980 • 67 citations

Relative activities of glutamine synthetase and glutaminase in mammalian synaptosomes

1979 • 66 citations

Evidence for a role of glutamate decarboxylase activity as a regulatory mechanism of cerebral excitability

1975 • 66 citations

Interactions between putative neurotransmitters in the brain

1978 • 66 citations

POSTNATAL CHANGES IN THE POTASSIUM‐STIMULATED, CALCIUM‐DEPENDENT RELEASE OF RADIOACTIVE GABA AND GLYCINE FROM SLICES OF RAT CENTRAL NERVOUS TISSUE

1975 • 65 citations

D‐ AND L‐STEREOISOMERS OF ALLYLGLYCINE: CONVULSIVE ACTION AND INHIBITION OF BRAIN L‐GLUTAMATE DECARBOXYLASE

1977 • 65 citations

The γ‐Aminobutyrate Content of Nerve Endings (Synaptosomes) in Mice After the Intramuscular Injection of γ‐Aminobutyrate‐Elevating Agents: A Possible Role in Anticonvulsant Activity

1980 • 64 citations

In Vivo Release of Endogenous γ‐Aminobutyric Acid from Rat Striatum: Effects of Muscimol, Oxotremorine, and Morphine

1980 • 64 citations

Release of neurotransmitters and depletion of synaptic vesicles in cerebral cortex slices by alpha-latrotoxin from black widow spider venom.

1978 • 63 citations

IN VIVO RELEASE OF ENDOGENOUS GABA FROM RAT SUBSTANTIA NIGRA MEASURED BY A NOVEL METHOD

1979 • 63 citations

Differential effects of n‐dipropylacetate and amino‐oxyacetic acid on Gm‐aminobutyric acid levels in discrete areas of rat brain¹

1979 • 61 citations

An artifact in the radiochemical assay of brain mitochondrial glutamate decarboxylase

1973 • 61 citations

Aminooxyacetic acid induced changes in γ-aminobutyrate metabolism at the subcellular level

1978 • 61 citations

Uptake and release of [14C]GABA from rabbit retina synaptosomes

1977 • 61 citations

Amygdaloid Kindling and the GABA System

1980 • 61 citations

THE SPONTANEOUS AND ELECTRICALLY EVOKED RELEASE, FROM SLICES OF GUINEA‐PIG CEREBRAL CORTEX, OF ENDOGENOUS AMINO ACIDS LABELLED VIA METABOLISM OF <scp>d</scp>‐[U‐¹⁴C]GLUCOSE

1978 • 61 citations

Mechanism of inactivation of .gamma.-aminobutyric acid-.alpha.-ketoglutaric acid aminotransferase by 4-amino-5-halopentanoic acids

1981 • 61 citations

Development of rat brain uptake and calcium-dependent release of GABA

1978 • 60 citations

METABOLISM OF POLYAMINES IN MOUSE NEUROBLASTOMA CELLS IN CULTURE:¹ FORMATION OF GABA AND PUTREANINE

1975 • 60 citations

INFLUENCE OF DIETARY PYRIDOXINE ON GLUTAMIC DECARBOXYLASE ACTIVITY OF BRAIN

1951 • 59 citations

Neurohumoral Coding of Brain Function

1973 • 59 citations

CORRELATIVE CHANGES OF PYRIDOXAL KINASE PYRIDOXAL‐5′‐PHOSPHATE AND GLUTAMATE DECARBOXYLASE IN BRAIN, DURING DRUG‐INDUCED CONVULSIONS

1969 • 59 citations

Effect of apomorphine on the GABA turnover in the DA cell group rich area of the mesencephalon. Evidence for the involvement of an inhibitory gabergic feedback control of the ascending DA neurons

1975 • 58 citations

Aminooxyacetic acid: Correlation between biochemical effects, anticonvulsant action and toxicity in mice

1978 • 58 citations

NEUROCHEMICAL ASPECTS OF NEURONAL ONTOGENESIS IN THE DEVELOPING RAT CEREBELLUM: CHANGES IN NEUROTRANSMITTER AND POLYAMINE SYNTHESIZING ENZYMES

1979 • 57 citations

POTASSIUM‐INDUCED RELEASE OF [³H]GABA AND OF [³H]NORADRENALINE FROM NORMAL AND RESERPINIZED RAT BRAIN CORTEX SLICES. DIFFERENCES IN CALCIUMDEPENDENCY, AND IN SENSITIVITY TO POTASSIUM IONS

1977 • 57 citations

Effect of Tetanus Toxin on Transmitter Release from the Substantia Nigra and Striatum In Vitro

1980 • 57 citations

GABAergic denervation of rat substantia nigra: functional and pharmacological properties

1980 • 57 citations

The effect of lanthanum ions on acetylcholine in frog muscle.

1980 • 56 citations

CALCIUM‐INDUCED RELEASE OF γ‐AMINOBUTYRIC ACID FROM SYNAPTOSOMES: EFFECTS OF TRANQUILIZER DRUGS

1977 • 55 citations

The Effects of Scorpion Venom Toxin on the Release of Amino Acid Neurotransmitters from Cerebral Cortex In Vivo and In Vitro

1980 • 55 citations

K+-stimulated release of labeled γ-aminobutyrate, glycine and taurine in slices of several regions of rat central nervous system

1978 • 55 citations

Differential decrease of GABA in the substantia nigra and other discrete regions of the rabbit brain during the preictal period of methoxypyridoxine-induced seizures

1976 • 55 citations

Glutamate decarboxylase activity in the rat posterior pituitary, pineal gland, dorsal root ganglion and superior cervical ganglion

1976 • 54 citations

PROPERTIES OF <scp>l</scp>‐GLUTAMATE DECARBOXYLASE FROM BRAINS OF ADULT AND NEWBORN MICE¹

1976 • 54 citations

Modulation of γ-aminobutyric acid transport in nerve endings: Role of extracellular γ-aminobutyric acid and of cationic fluxes

1978 • 54 citations

Effect of γ-vinyl GABA on bicuculline-induced seizures

1981 • 52 citations

STUDIES ON THE REGULATION OF GABA SYNTHESIS: THE INTERACTION OF ADENINE NUCLEOTIDES AND GLUTAMATE WITH BRAIN GLUTAMATE DECARBOXYLASE

1978 • 52 citations

Changes in concentrations of polyamines and γ‐aminobutyric acid and their formation in chick embryo brain during development

1978 • 52 citations

PYRIDOXAL PHOSPHATE AND GLUTAMATE DECARBOXYLASE IN SUBCELLULAR PARTICLES OF MOUSE BRAIN AND THEIR RELATIONSHIP TO CONVULSIONS¹

1973 • 52 citations

Effects of various substituted hydrazones and hydrazines of pyridoxal-5'-phosphate on brain glutamate decarboxylase

1969 • 52 citations

PURIFICATION OF L‐GLUTAMIC ACID DECARBOXYLASE FROM CATFISH BRAIN

1979 • 51 citations

Pig brain 4-aminobutyrate 2-ketoglutarate transaminase. Purification, kinetics and physical properties

1974 • 51 citations

γ-Aminobutyric acid metabolism in rat brain following chronic oral administration of ethanolamine O-sulphate

1980 • 51 citations

gamma‐Aminobutyric acid efflux from sympathetic glial cells: effect of ‘depolarizing’ agents.

1979 • 51 citations

REGIONAL CHANGES IN CEREBRAL GABA CONCENTRATION AND CONVULSIONS PRODUCED BY <scp>d</scp> AND BY <scp>l</scp>‐ALLYLGLYCINE

1978 • 50 citations

Potassium-stimulated release of GABA, glycine, and taurine from the chick retina

1978 • 50 citations

Golgi-impregnated amacrine cells and GABAergic retinal neurons: A comparison of dendritic, immunocytochemical, and histochemical stratification in the inner plexiform layer of rat retina

1981 • 50 citations

GLUTAMATE DECARBOXYLASE ACTIVITY IN STRIATAL SLICES: CHARACTERIZATION OF THE INCREASE FOLLOWING DEPOLARIZATION^{1, 2}

1979 • 50 citations

VITAMIN B₆AND BRAIN FUNCTION IN ANIMALS AND MAN

1969 • 49 citations

How selective is high affinity uptake of GABA into inhibitory nerve terminals?

1974 • 49 citations

Uptake of GABA by neuronal and nonneuronal cells in dispersed cell cultures of postnatal rat cerebellum

1975 • 49 citations

EFFECTS OF DEPOLARIZATION ON COFACTOR REGULATION OF GLUTAMIC ACID DECARBOXYLASE IN SUBSTANTIA NIGRA SYNAPTOSOMES

1979 • 48 citations

Spontaneous and potassium-evoked release of 3H-GABA newly synthesized from 3H-glutamine in slices of the rat substantia nigra

1979 • 48 citations

ELECTRICALLY INDUCED RELEASE OF [3H]GABA FROM NEOCORTICAL THIN SLICES. EFFECTS OF STIMULUS WAVEFORM AND OF AMINO-OXYACETIC ACID

1976 • 48 citations

In vivo release of endogenously synthesized [3H]GABA from the cat substantia nigra and the pallido-entopeduncular nuclei

1980 • 48 citations

[3H]gamma‐Aminobutyric acid uptake into neuroglial cells of rat superior cervical sympathetic ganglia.

1979 • 48 citations

NET UPTAKE OF L‐GLUTAMATE AND GABA BY HIGH AFFINITY SYNAPTOSOMAL TRANSPORT SYSTEMS

1978 • 48 citations

GLUTAMIC ACID DECARBOXYLASE (GAD) IN MAMMALIAN TISSUE OUTSIDE THE CENTRAL NERVOUS SYSTEM, AND ITS POSSIBLE RELEVANCE TO HEREDITARY VITAMIN B₆ DEPENDENCY WITH SEIZURES*

1969 • 48 citations

Stereochemistry of Reactions Catalysed by Mammalian‐Brain <scp>L</scp>‐Glutamate 1‐Carboxy‐lyase and 4‐Aminobutyrate: 2‐Oxoglutarate Aminotransferase

1979 • 47 citations

The Synthesis and Activity of cis‐and trans‐2‐(Aminomethyl) cyclopropanecarboxylic Acid as Conformationally Restricted Analogues of GABA

1980 • 47 citations

Net uptake of gamma-aminobutyric acid by a high affinity synaptosomal transport system.

1977 • 47 citations

4‐Aminobutyrate Aminotransferase Fluorescence Studies

1978 • 47 citations

Potassium-stimulated, calcium-dependent release of [3H]GABA from neuron- and glia-enriched cultures of cells dissociated from rat cerebellum

1981 • 47 citations

Vitamin B6 Metabolism in Infants and Children

1964 • 46 citations

The effect of cochlear nerve lesion on the release of glutamate, aspartate, and GABA from cat cochlear nucleus, in vitro

1980 • 46 citations

A Toxin Purified from the Venom of Black Widow Spider Affects the Uptake and Release of Radioactive γ‐Amino Butyrate and N‐Epinephrine from Rat Brain Synaptosomes

1979 • 46 citations

Immunocytochemical localization of GABA neurons in the rabbit and frog retina

1980 • 46 citations

Effects of gabaculine, a new potent inhibitor of gamma-aminobutyrate transaminase, on the brain gamma-aminobutyrate content and convulsions in mice

1977 • 46 citations

EFFECTS OF AMINOOXYACETIC ACID AND <scp>l</scp>‐GLUTAMIC ACID‐γ‐HYDRAZIDE ON GABA METABOLISM IN SPECIFIC BRAIN REGIONS

1978 • 45 citations

Uptake and Localization of Transmitter Amino Acids in the Nervous System

1975 • 45 citations

Regulation of GABA Metabolism in Discrete Rabbit Brain Regions under Methoxypyridoxine—Regional Differences in Cofactor Saturation and the Preictal Activation of Glutamate Decarboxylase Activity¹

1980 • 44 citations

Effects of calcium on the potassium-stimulated release of radioactive β-alanine and γ-aminobutyric acid from slices of rat cerebral cortex and spinal cord

1977 • 44 citations

A model of GABA transport by cortical synaptosomes from the long‐evans rat

1979 • 43 citations

Cerebral amino acid transport in vitro during development: A kinetic analysis

1970 • 43 citations

Functional assessment of GABA uptake or exchange by synaptosomal fractions

1976 • 43 citations

SOME EFFECTS OF DIETARY VITAMIN B₆ DEFICIENCY ON γ‐AMINOBUTYRIC ACID METABOLISM IN DEVELOPING RAT BRAIN

1972 • 43 citations

High-affinity uptake of ?-aminobutyric acid in cultured glial and neuronal cells

1979 • 42 citations

Autoradiography of GABA in the rat hypothalamic median eminence

1980 • 42 citations

The uptake of gaba by clonal nerve and glia

1975 • 42 citations

Production of an antiserum to rat brain glutamate (GAD)/cysteine sulfinate (CSD) decarboxylase

1980 • 42 citations

Interactions between neurons and astrocytes in the turnover of GABA and glutamate

1980 • 42 citations

Solubilisation and reconstitution of the γ-aminobutyric acid transporter from rat brain

1978 • 41 citations

Selective release of newly synthesised and newly captured GABA from synaptosomes by potassium depolarisation

1975 • 41 citations

KINETICS OF BRAIN GLUTAMATE DECARBOXYLASE. INTERACTIONS WITH GLUTAMATE, PYRIDOXAL 5‐PHOSPHATE AND GLUTAMATE‐PYRIDOXAL 5‐PHOSPHATE SCHIFF BASE¹

1977 • 41 citations

STUDY ON THE INHIBITION OF BRAIN GLUTAMATE DECARBOXYLASE BY PYRIDOXAL PHOSPHATE OXIME‐O‐ACETIC ACID

1971 • 41 citations

Distribution and tissue specificity of 4-aminobutyrate-2-oxoglutarate aminotransferase

1978 • 40 citations

GABA Agonists and Uptake Inhibitors of Restricted Conformations: Structure-Activity Relations

1978 • 39 citations

Irreversible inactivation of pig brain γ-aminobutyric acid-α-ketoglutarate transaminase by 4-amino-5-halopentanoic acids

1980 • 39 citations

STIMULATION BY PHOSPHATE OF THE ACTIVATION OF GLUTAMATE APODECARBOXYLASE BY PYRIDOXYL‐5′‐PHOSPHATE AND ITS IMPLICATIONS FOR THE CONTROL OF GABA SYNTHESIS

1979 • 38 citations

Effect of ethanolamine-O-sulphate on regional gaba metabolism in the mouse brain

1977 • 37 citations

RELATIONSHIPS AMONG PYRIDOXAL PHOSPHATE, VITAMIN B₆‐DEFICIENCY, AND CONVULSIONS INDUCED BY 1,1‐DIMETHYLHYDRAZINE

1967 • 37 citations

Relationships between pyridoxal phosphate availability, activity of vitamin B6-dependent enzymes and convulsions

1971 • 36 citations

The Role of γ-Aminobutyric Acid Metabolism in the Regulation of Cerebral Excitability

1974 • 36 citations

VITAMIN B6 DEFICIENCY IN INFANTS&lt;subtitle&gt;A Follow-Up Study&lt;/subtitle&gt;

1955 • 36 citations

Development of neurotransmitter uptake in regions of the chick brain

1977 • 36 citations

The interaction of baclofen (β-(4-chlorophenyl)GABA) with GABA systems in rat brain: evidence for a releasing action

1978 • 36 citations

Uptake, Exchange and Release of GABA in Isolated Nerve Endings

1978 • 36 citations

Effects of Pyridoxine Withdrawal on Cerebral Circulation and Metabolism in a Pyridoxine-dependent Child

1959 • 36 citations

Effects of pentobarbital and Ca2+ on the resting and k+-stimulated release of several endogenous neurotransmitters from rat midbrain slices

1980 • 36 citations

The action of γ-vinyl-GABA and γ-acetylenic-GABA on the resting and stimulated release of GABA in vivo

1980 • 35 citations

THE FORMATION OF GLUTAMATE, ASPARTATE AND GABA IN THE RAT RETINA; GLUCOSE AND GLUTAMINE AS PRECURSORS

1979 • 35 citations

Studies on the relationship between Ca2+ efflux from mitochondria and the release of amino acid neurotransmitters

1980 • 35 citations

Developmental studies of the uptake of choline, gaba and dopamine by crude synaptosomal preparations after in vivo or in vitro lead treatment

1980 • 35 citations

Behavioral and biochemical analysis of gaba-mediated inhibition in the early chick embryo

1979 • 35 citations

High-affinity GABA and glutamate transport in developing nerve ending particles

1978 • 35 citations

The Localization and Metabolism of Neuroactive Amino Acids in the Retina

1978 • 35 citations

Electrically induced, calcium-dependent release of endogenous GABA from rat brain cortex slices

1978 • 35 citations

In vivo changes in the GABA content of nerve endings (synaptosomes) induced by inhibitors of GABA uptake

1980 • 34 citations

Effects of anticonvulsants on the in vivo and in vitro release of gaba

1981 • 34 citations

Relationships between GABA and polyamines in developing rat brain

1980 • 34 citations

The autoradiographic localization of the gaba-releasing nerve terminals in cerebellar glomeruli

1975 • 34 citations

The effect of penicillin on the release of γ-aminobutyric acid from cerebral cortex slices

1979 • 34 citations

Studies on the control of 4-aminobutyrate metabolism in ‘synaptosomal’ and free rat brain mitochondria

1976 • 33 citations

Isolation and inhibitory activity of gabaculine, a new potent inhibitor of γ‐aminobutyrate aminotransferase produced by a Streptomyces

1977 • 33 citations

Glutamate holodecarboxylase levels and the regulation of GABA synthesis

1980 • 33 citations

THE EFFECT OF <scp>dl</scp>‐ALLYLGLYCINE ON POLYAMINE AND GABA METABOLISM IN MOUSE BRAIN

1979 • 33 citations

Does uptake limit the action of GABA agonists in vivo? Experiments with muscimol, isoguvacine and THIP in cat spinal cord

1978 • 32 citations

Purification and partial characterisation of 4‐aminobutyrate 2‐ketoglutarate transaminase from human brain

1974 • 32 citations

GABA uptake in astrocytes in primary cultures: Coupling with two sodium ions

1980 • 32 citations

Evidence for the local synthesis of a transmitter enzyme (glutamic acid decar☐ylase) in crayfish peripheral nerve

1976 • 32 citations

GABA depletion and behavioural changes produced by intraventricular putrescine in chicks

1980 • 32 citations

Regulatory Mechanisms of Synaptic Transmission

1981 • 31 citations

The inhibition of mouse brain glutamate decarboxylase by some structural analogues of L-glutamic acid

1977 • 31 citations

METABOLIC PROPERTIES OF A PURIFIED PREPARATION OF LARGE FRAGMENTS OF THE CEREBELLAR GLOMERULI: GLUCOSE METABOLISM AND AMINO ACID UPTAKE

1976 • 31 citations

A COMPARATIVE STUDY OF L‐GLUTAMATE DECARBOXYLASE FROM MOUSE BRAIN AND BOVINE HEART WITH PURIFIED PREPARATIONS¹

1977 • 30 citations

Effects of Gabaculine on the uptake, binding and metabolism of GABA

1977 • 30 citations

Effect of aminooxyacetic acid (AOAA) on GABA levels in some parts of the rat brain

1980 • 29 citations

Convulsions or flaccid paralysis induced by ruthenium red depending on route of administration

1976 • 28 citations

The effect of light and potassium depolarization on the release of endogenous amino acids from the isolated rat retina

1978 • 28 citations

Brain Glutamate Decarboxylase: Properties of Its Calcium‐Dependent Binding to Liposomes and Kinetics of the Bound and the Free Enzyme

1980 • 28 citations

2-PyrroIidinone—A cyclization product of γ-aminobutyric acid detected in mouse brain

1978 • 28 citations

In vivo release of endogenous GABA in the cat hypothalamus

1979 • 27 citations

GABA FLUXES IN PRESYNAPTIC NERVE ENDINGS FROM IMMATURE RATS

1979 • 27 citations

Immunocytochemistry of glutamate decar☐ylase in the deafferented habenula

1981 • 26 citations

Uptake and Exchange of GABA and Glutamate in Isolated Nerve Endings

1976 • 26 citations

Effects of GABA-Analogues on the High-Affinity Uptake of GABA in Astrocytes in Primary Cultures

1979 • 26 citations

THE INFLUENCE OF SODIUM, POTASSIUM AND LANTHANUM ON AMINO ACID RELEASE FROM SPINAL–MEDULLARY SYNAPTOSOMES

1975 • 26 citations

Compartmentation of Amino Acids in Brain: The GABA-Glutamine-Glutamate Cycle

1978 • 26 citations

Actions of β‐Bungarotoxin on Amino Acid Transmitter Release

1980 • 25 citations

Biochemical consequences of reactions catalyzed by GAD and GABA-T

1980 • 25 citations

Metabolic Compartmentation in the Brain and Effects of Metabolic Inhibitors

1975 • 25 citations

Accumulation of glutamic acid decarboxylase in the proximal parts of presumed GABA-ergic neurones after axotomy

1975 • 25 citations

Gaba-neuro-transmitters : pharmacochemical, biochemical, and pharmacological aspects : proceedings of the Alfred Benzon Symposium 12 held at the premises of the Royal Danish Academy of Sciences and Letters, Copenhagen 21-25 May 1978

1979 • 25 citations

Evaluation of increases in nerve terminal-dependent vs nerve terminal-independent compartments of GABA in vivo

1980 • 24 citations

Comparison of DABA and GABA Transport into Plasma Membrane Vesicles Derived from Synaptosomes

1981 • 24 citations

γ-Aminobutyric acid in subcellular fractions of mouse brain and its relation to convulsions

1979 • 23 citations

THE IRREVERSIBLE INHIBITION OF BRAIN L‐GLUTAMATE‐I‐DECARBOXYLASE BY (2RS,3E)‐2‐METHYL‐3,4‐DIDEHYDROGLUTAMIC ACID

1979 • 23 citations

Inhibition of different molecular forms of brain glutamic acid decarboxylase (GAD) with ATP

1978 • 23 citations

CALCIUM‐DEPENDENT BINDING OF BRAIN GLUTAMATE DECARBOXYLASE TO PHOSPHOLIPID VESICLES

1978 • 23 citations

KINETICS OF BRAIN GLUTAMATE DECARBOXYLASE. INHIBITION STUDIES WITH N-(5'-PHOSPHOPYRIDOXYL) AMINO ACIDS

1977 • 23 citations

Peripheral sensory stimulation and the release of transmitter amino acids in vivo from specific regions of cerebral cortex

1979 • 23 citations

Effects of β-bungarotoxin and tityustoxin on accumulation of putative amino acid neurotransmitters by rat cortex synaptosomes

1980 • 22 citations

Differences in some properties of newborn and adult brain glutamate decarboxylase

1975 • 22 citations

Gabaculine and isogabaculine: biochemistry and pharmacology in mice

1979 • 22 citations

PARTIAL PURIFICATION OF DROSOPHILA GLUTAMATE DECARBOXYLASE¹

1979 • 22 citations

Effect of di-n-propylacetate and ?-acetylenic GABA on hyperbaric oxygen-induced seizures and GABA metabolism

1977 • 22 citations

THE EFFECTS OF SOME NEWER ANAESTHETICS ON THE IN VITRO ACTIVITY OF GLUTAMATE DECARBOXYLASE AND GABA TRANSAMINASE IN CRUDE BRAIN EXTRACTS AND ON THE LEVELS OF AMINO ACIDS IN VIVO

1975 • 22 citations

Field desorption mass spectrometry of carboxylate salts: characteristic spectra and effects of added complexing agents

1978 • 21 citations

The spontaneous and evoked release of newly synthesized [14C]GABA from rat cerebral cortex, in vitro

1977 • 21 citations

Glutamic acid decarboxylase activity in striatal slices: Persistent increase following depolarization

1978 • 21 citations

Characterization and cellular and subcellular localization of GABA-transaminase

1980 • 21 citations

Seizure susceptibility in the developing mouse and its relationship to glutamate decarboxylase and pyridoxal phosphate in brain

1975 • 21 citations

The GABA system in the mammalian habenula

1980 • 21 citations

A radiometric microassay for glutamic acid decar☐ylase

1979 • 21 citations

Differential effects of GABA analogues and zinc on glutamate decarboxylase, 4‐aminobutyric‐2‐oxoglutaric acid transaminase and succinate semialdehyde dehydrogenase in rat brain tissue

1979 • 21 citations

Net uptake of gamma-aminobutyric acid by a high-affinity system of rat brain synaptosomes.

1981 • 21 citations

The inhibition by substrate analogues of γ-aminobutyrate aminotransferase from mitochondria of different subcellular fractions of rat brain

1977 • 20 citations

The role of 2-keto-4-pentenoic acid in seizures induced by allylglycine

1978 • 20 citations

Measuring changes in cerebral glutamate and gaba metabolism prior to convulsions induced by 3-mercaptopropionate

1978 • 20 citations

Glutamine Metabolism in Brain

1980 • 20 citations

Alterations in the compartmentalized metabolism of glutamic acid with changed cerebral conditions

1980 • 19 citations

In vivo [14C]amino acid profiles in discrete hypothalamic regions during push-pull perfusion in the unrestrained rat

1979 • 19 citations

Effect of penicillin on transmitter release from rat cortical tissue

1980 • 19 citations

The role of Ca2+ in the protoveratrine-induced release of γ-aminobutyrate from rat brain slices

1980 • 19 citations

Amino Acids and the Brain

1974 • 19 citations

Gamma-aminobutyric acid homoexchange in sensory ganglia

1976 • 19 citations

Transport of G AB A, β‐Alanine and Glutamate into Perikarya of Postnatal Rat Cerebellum

1980 • 19 citations

THE UTILIZATION OF GLUTAMINE BY THE RETINA: AN AUTORADIOGRAPHIC AND METABOLIC STUDY

1978 • 18 citations

EFFECT OF NEUROTROPIC AGENTS ON TOTAL PYRIDOXAL PHOSPHATE AND ON THE ACTIVITY OF THE DECARBOXYLASE OF AROMATIC AMINO ACIDS AS WELL AS OF OTHER PYRIDOXAL PHOSPHATE‐DEPENDENT ENZYMES IN RAT BRAIN¹

1974 • 18 citations

Metabolic Compartmentation of the Glutamate - Glutamine System: Glial Contribution

1978 • 18 citations

INHIBITION OF BRAIN GLUTAMATE DECARBOXYLASE BY 2‐KETO‐4‐PENTENOIC ACID, A METABOLITE OF ALLYLGLYCINE¹

1979 • 17 citations

The filum terminale of the frog spinal cord, a non transformed glial preparation: I. Morphology and uptake of γ-aminobutyric acid

1979 • 17 citations

Molecular basis for the irreversible inhibition of 4-aminobutyric acid:2-oxoglutarate and L-ornithine:2-oxoacid aminotransferases by 3-amino-1,5-cyclohexadienyl carboxylic acid (isogabaculline).

1979 • 17 citations

Effect of dietary GABA and protein on growth, food intake and GABA metabolism in the rat

1980 • 16 citations

IMMUNOLOGICAL QUANTITATION OF GLUTAMIC ACID DECARBOXYLASE IN DEVELOPING MOUSE BRAIN¹

1977 • 16 citations

Ornithine as a Precursor for y‐Aminobutyric Acid in Mammalian Brain

1980 • 16 citations

The effect of the convulsant allylglycine (2-amino-4-pentenoic acid) on the activity of glutamic acid decarboxylase and the concentration of GABA in different regions of guinea pig brain

1976 • 16 citations

Transmitter synthesis and convulsant drugs: Effects of pyridoxal phosphate antagonists and allylglycine

1978 • 16 citations

Effects of ethanolamine‐O‐sulphate and γ‐acetylenic‐GABA on GABA content, GAD and GABA‐T in various areas of chick brain after intraventricular microinjection

1979 • 15 citations

Changes in some properties of glutamate decarboxylase activity during the maturation of the brain

1976 • 15 citations

Factors influencing the activation and inactivation of glutamate decarboxylase

1980 • 15 citations

A Comparative study of the utilization of glucose, acetate, glutamine and GABA as precursors of amino acids by retinae of the rat, frog, rabbit and pigeon

1975 • 15 citations

Developmental changes in activity of choline acetyltransferase. acetyl‐cholinesterase and glutamic acid decarboxylase in the central nervous system of the toad. Xenopus Laevis

1976 • 15 citations

Sodium dependence of GABA transport in rat hypothalamic synaptosomes

1980 • 15 citations

A comparison of γ‐aminobutyric acid metabolism in neurones versus glial cells using intact isolated retinae

1977 • 15 citations

Calcium Transport and the Release of Neurotransmitters: Effects of Drugs in Vivo and in Vitro

1981 • 15 citations

Bidirectional Movement of γ‐Aminobutyric Acid in Rat Spinal Cord Slices

1980 • 14 citations

Purification of l-glutamate decarboxylase by affinity chromatography

1977 • 14 citations

A dual mechanism for the anticonvulsant action of aminooxyacetic acid

1976 • 14 citations

Incorporation of rdiolabelled sugars into synaptic junctional macromolecules from chick brain

1980 • 13 citations

Stimulus-secretion coupling processes in brain: Dependence upon extracellular calcium concentration

1979 • 13 citations

Effect of 6-azauracil, and of certain structurally similar compounds, on three pyridoxal-phosphate requiring enzymes involved in neurotransmitter metabolism

1979 • 13 citations

The release of endogenous amino acids into the vitreous of the intact eye of the albino rat: effect of light, potassium, and ouabain

1981 • 13 citations

Stimulation-dependent depression of neurotransmitter release in brain: [Ca2+]0 dependence

1978 • 12 citations

Turnover Numbers of ?-Aminobutyrate Aminotransferase in Some Regions of Rat Brain

1980 • 12 citations

Thiopental inhibition of γ-aminobutyrate transaminase in rat brain synaptosomes

1979 • 12 citations

Effects of the ionophores X537A and A23187 on GABA, glycine, and taurine release from chick retinal subcellular fractions

1980 • 11 citations

The release of endogenous amino acids from rat visual cortex by calcium ions in the presence of the calcium ionophores X537A and A23187

1977 • 11 citations

Brain and blood levels of allylglycine in mice following doses sufficient to inhibit glutamate decarboxylase

1977 • 11 citations

Essential arginine residues at the pyridoxal phosphate binding site of brain γ-aminobutyrate aminotransferase

1980 • 11 citations

Neurotransmitters of the Mammalian Visual System

1978 • 11 citations

GABA metabolism and cerebral protein synthesis

1975 • 11 citations

Ontogeny of ACh and GABA synthesis during development of the Xenopus retina

1978 • 11 citations

[3H]GABA release in synaptosomal fractions after intracranial administration of ruthenium red

1978 • 11 citations

Effect of 5-hexyne-1,4-diamine on brain 4-aminobutyric acid metabolism in rats and mice

1979 • 11 citations

On the gaba transport in fractions of astrocytes and nerve-terminals

1980 • 10 citations

Bidirectional movement of γ-aminobutyric acid in cerebral cortex slices incubated in small volumes of medium

1979 • 10 citations

STUDIES ON THE RELATIONSHIP BETWEEN GABA SYNTHESIS AND PROTEIN SYNTHESIS IN BRAIN

1976 • 9 citations

Functional role of arginine residues in glutamic acid decarboxylase from brain and bacteria

1978 • 9 citations

Allylglycine: Intranigral effects and reappraisal of actions on the GABA system

1979 • 9 citations

The effect of depolarizing potassium concentrations on the efflux of GABA from rat dorsal medulla in vivo and from slices and synaptosomes

1979 • 9 citations

The influence in rabbits and rats of gamma-acetylenic GABA on seizures generated by pentylenetetrazol

1980 • 9 citations

On the Role of Mitochondria in Neurotransmitter Release

1981 • 9 citations

Evidence against the existence of glutamate decarboxylase (II) in rat brain mitochondria

1976 • 9 citations

Isolation of 4.5‐Dihydroxyisophthalic Acid, an Inhibitor of Brain Glutamate Decarboxylase, Produced by a Streptomyces Species

1978 • 9 citations

Localization of Transmitter Amino Acids: Application to Hippocampus and Septum

1978 • 9 citations

Comments on Localization of Neurotransmitters in the Basal Ganglia

1978 • 9 citations

4-Aminobutryrate aminotransferase, the reaction of lysine residues connected with enzymatic activity

1981 • 8 citations

Effect of pentobarbitone on the spontaneous efflux of γ-amino acids from rabbit retina

1979 • 8 citations

Synthesis of affinity chromatography resins for the purification of brain glutamate decarboxylase

1977 • 8 citations

Purification and regulation of L-glutamate decarboxylase

1980 • 8 citations

An Analysis of ?-Aminobutyrate Receptors and Uptake by Isolated Purkinje Cells

1980 • 8 citations

Kinetics of and rate equations for the uptake of alpha-amino-isobutyric acid and gamma-aminobutyric acid by mouse brain slices incubated in a glucose-free medium containing pyruvate as the energy source

1981 • 7 citations

Influx of γ‐Aminobutyric Acid and α‐Aminoisobutyric Acid into Mouse Cerebrum Slices Incubated in a Pyruvate Medium with or without Added Glucose or Glucose Analogues Compared with Influx from a Glucose Medium

1980 • 7 citations

Evidence for A Synthesis-Dependent Release of GABA

1976 • 7 citations

A comparison of the kinetic properties of mouse brain glutamate decarboxylase activities in the mitochondrial and supernatant fractions

1976 • 6 citations

Neurotransmitters in the Amygdala: A Brief Review

1978 • 6 citations

Effect of GABA agonists and modulators on prolactin release

1980 • 6 citations

Release of exogenous γ-[³H]aminobutyric acid during seizure activity in chronically denervated and normal cat cortex

1979 • 6 citations

Stereochemical aspects of the metabolism of 4‐aminobutyrate in mouse brain

1979 • 5 citations

Tetrodotoxin inhibition in vitro of protoveratrine A-activated glutamate decarboxylase in synaptosomes

1980 • 5 citations

The effects of allylglycine on GABA synthesis in vivo

1978 • 5 citations

Glutamate Decarboxylase, Properties and the Synaptic Function of GABA

1978 • 4 citations

Convulsant drug action on GABA and taurine synthesis

1979 • 4 citations

Kinetics of brain glutamate decarboxylase. Dead‐end and product inhibition studies¹

1978 • 4 citations

GABA Markers in the Hypothalamus : Topographical Distribution and Origin

1978 • 4 citations

Activation by adenosine-5′-triphosphate of glutamic decarboxylase from a subcellular fraction of mouse brain

1979 • 4 citations

Transport and binding of GABA and related amino acids by peripheral glial cells of dorsal root ganglia

1980 • 3 citations

GABAergic Mechanisms and Their Relationship to Some Hormones in the Central Nervous System

2015 • 3 citations

Studies on GABA release in vivo using a simple method for perfusion of the fourth ventricle of the rat

1980 • 3 citations

Effects of γ-acetylenic GABA and γ-vinyl GABA on electrically-induced spinal cord convulsions and on spinal cord GABA concentration

1980 • 3 citations

Glutamate decarboxylase activity in chick brain and retina

1979 • 3 citations

Properties of GABA transport during development in mouse brain

1980 • 2 citations

Appendix to gamma-Aminobutyric acid efflux from sympathetic glial cells: effect of depolarizing agents. Electrical responses of presumed sympathetic neuroglial cells to K+ ions and to preganglionic nerve stimulation.

1979 • 2 citations

GABA Release in Vivo and in Vitro: Responses to Physiological and Chemical Stimuli

1981 • 2 citations