GABA Agonists and Uptake Inhibitors of Restricted Conformations: Structure-Activity Relations

GABA in nervous system function

1977 • 1,087 citations

THE EXCITATION AND DEPRESSION OF SPINAL NEURONES BY STRUCTURALLY RELATED AMINO ACIDS

1960 • 853 citations

Bicuculline, an antagonist of GABA and synaptic inhibition in the spinal cord of the cat

1971 • 685 citations

Properties of γ-aminobutyric acid (GABA) receptor binding in rat brain synaptic membrane fractions

1975 • 637 citations

GABA, Bicuculline and Central Inhibition

1970 • 545 citations

GABA in nervous system function

1976 • 529 citations

A new class of GABA agonist

1977 • 338 citations

INHIBITION OF GABA UPTAKE IN RAT BRAIN SLICES BY NIPECOTIC ACID, VARIOUS ISOXAZOLES AND RELATED COMPOUNDS

1975 • 329 citations

Behavioural stimulation induced by muscimol and other GABA agonists injected into the substantia nigra

1977 • 279 citations

STRUCTURE AND BIOLOGICAL ACTIVITY OF A SERIES OF CONFORMATIONALLY RESTRICTED ANALOGUES OF GABA

1975 • 267 citations

Central actions of ibotenic acid and muscimol

1968 • 208 citations

INHIBITION OF THE UPTAKE OF GABA AND RELATED AMINO ACIDS IN RAT BRAIN SLICES BY THE OPTICAL ISOMERS OF NIPECOTIC ACID

1976 • 202 citations

Central GABA receptor agonists: Comparison of muscimol and baclofen

1976 • 182 citations

CIS‐ AND TRANS‐4‐AMINOCROTONIC ACID AS GABA ANALOGUES OF RESTRICTED CONFORMATION

1975 • 176 citations

GABA receptor binding with 3H (+) bicuculline–methiodide in rat CNS

1977 • 175 citations

Betel nut constituents as inhibitors of γ-aminobutyric acid uptake

1975 • 175 citations

gamma-Aminobutyric acid (Gaba) and the dopamine hypothesis of schizophrenia

1977 • 141 citations

Molecular and Quantum Pharmacology

1974 • 128 citations

A NEW CHEMICAL METHOD FOR QUANTIFYING MELANIN

1976 • 126 citations

Environmental Effects on Molecular Structure and Properties

1976 • 116 citations

COMPETITIVE INHIBITION OF GABA UPTAKE IN RAT BRAIN SLICES BY SOME GABA ANALOGUES OF RESTRICTED CONFORMATION

1972 • 105 citations

Effects of the Areca nut constituents arecaidine and guvacine on the action of GABA in the cat central nervous system

1977 • 103 citations

Neurobiology and pharmacology of Huntington's disease

1977 • 96 citations

The in vivo inactivation of GABA and other inhibitory amino acids in the cat nervous system

1976 • 94 citations

The Structure of Muscimol, a GABA Analogue of Restricted Conformation.

1972 • 73 citations

Comments on “Is the African Plate Stationary?”

1973 • 59 citations

Transamination of analogues of γ-aminobutyric acid by extracts of rat brain mitochondria

1973 • 54 citations

Molecular orbital studies on the conformation of γ-aminobutyric acid and muscimol

1970 • 51 citations

Muscimol and the uptake of ?-aminobutyric acid by rat brain slices

1971 • 50 citations

Molecular orbital studies on the conformation of GABA (?-aminobutyric acid)

1975 • 37 citations

PROCEEDINGS OF THE BRITISH PHARMACOLOGICAL SOCIETY: 30th‐31st March, 1977: UNIVERSITY OF LIVERPOOL COMMUNICATIONS

1977 • 36 citations

Molecular Conformation of GABA

1971 • 32 citations

Effects of Gabaculine on the uptake, binding and metabolism of GABA

1977 • 30 citations

Fate of muscimol in the mouse.

1975 • 21 citations

Molecular orbital studies on the conformations of bicuculline and β-hydroxy GABA

1973 • 19 citations

Agonism and antagonism of γ-aminobutyric acid

1975 • 18 citations

Piperazic acid and related compounds as inhibitors of GABA uptake in rat brain slices

1977 • 16 citations

Configuration and Conformation of Bicuculline, a GABA Antagonist

1973 • 16 citations

Employment: Unemployed PhDs

1971 • 16 citations

NMR Studies of Solution Conformations of Physiologically Active Amino-Acids

1974 • 11 citations

Quantum-Mechanical Studies on the Effect of Water on the Conformation of Two Biologically Important Zwitterionic Systems: Polar Head of Phospholipids and Gaba

1976 • 9 citations

Low Frequency Radio Emission from Extensive Air Showers

1973 • 8 citations

Molecular orbital and proton magnetic resonance studies of bicuculline.

1973 • 7 citations