EFFECTS OF ELEVATED [K⁺]₀ ON THE RELEASE OF NEUROTRANSMITTERS FROM CORTICAL SYNAPTOSOMES: EFFLUX OR SECRETION?

[73] Spectrophotometric and turbidimetric methods for measuring proteins

1957 • 3,309 citations

Chemical Nature of Synaptic Transmission in Vertebrates

1974 • 1,613 citations

Stimulus‐secretion coupling: the concept and clues from chromaffin and other cells

1968 • 1,393 citations

A23187: A Divalent Cation Ionophore

1972 • 1,182 citations

Mechanism by which cyanine dyes measure membrane potential in red blood cells and phosphatidylcholine vesicles

1974 • 949 citations

Properties of γ-aminobutyric acid (GABA) receptor binding in rat brain synaptic membrane fractions

1975 • 637 citations

The timing of calcium action during neuromuscular transmission

1967 • 564 citations

Effects of potassium, veratridine, and scorpion venom on calcium accumulation and transmitter release by nerve terminals in vitro.

1975 • 559 citations

SODIUM‐DEPENDENT HIGH AFFINITY CHOLINE UPTAKE: A REGULATORY STEP IN THE SYNTHESIS OF ACETYLCHOLINE

1976 • 542 citations

Glial Cell Function: Uptake of Transmitter Substances

1971 • 460 citations

Methods of Neurochemistry

1973 • 454 citations

Transmitter release induced by injection of calcium ions into nerve terminals

1973 • 443 citations

Biochemical-physiology correlations in studies of the γ-aminobutyric acid system

1968 • 408 citations

Membrane potentials in pinched‐off presynaptic nerve ternimals monitored with a fluorescent probe: evidence that synaptosomes have potassium diffusion potentials.

1975 • 389 citations

Tritosol: A new scintillation cocktail based on Triton X-100

1975 • 389 citations

Choline uptake systems of rat brain synaptosomes

1973 • 387 citations

CHROMATOGRAPHIC AND ELECTROPHORETIC TECHNIQUES

1961 • 358 citations

Optical probes of membrane potential

1976 • 354 citations

The effect of veratridine on excitable membranes of nerve and muscle

2007 • 344 citations

Presynaptic calcium currents and their relation to synaptic transmission: Voltage clamp study in squid giant synapse and theoretical model for the calcium gate

1976 • 323 citations

Calcium and the Secretory Process

1974 • 318 citations

Aspartate and glutamate as possible transmitters of excitatory hippocampal afferents

1976 • 300 citations

Comparative studies of substrates and inhibitors of choline transport and choline acetyltransferase.

1975 • 280 citations

Effects of manganese and other agents on the calcium uptake that follows depolarization of squid axons

1973 • 271 citations

The characterisation of [3H]GABA uptake into the satellite glial cells of rat sensory ganglia

1974 • 246 citations

Autoradiographic localisation of [3H]GABA and [3H]glutamate over satellite glial cells

1974 • 230 citations

THE EFFECT OF ELECTRICAL STIMULATION AND HIGH POTASSIUM CONCENTRATIONS ON THE EFFLUX OF [³H] γ‐AMINOBUTYRIC ACID FROM BRAIN SLICES

1969 • 227 citations

Handbook of Psychopharmacology

1978 • 219 citations

METABOLISM OF BEDS OF MAMMALIAN CORTICAL SYNAPTOSOMES: RESPONSE TO DEPOLARIZING INFLUENCES

1972 • 215 citations

Tetanic and post‐tetanic rise in frequency of miniature end‐plate potentials in low‐calcium solutions

1971 • 212 citations

Responses of electrical potential, potassium levels, and oxidative metabolic activity of the cerebral neocortex of cats

1975 • 202 citations

RELEASE OF [³H]GAMMA-AMINOBUTYRIC ACID FROM GLIAL CELLS IN RAT DORSAL ROOT GANGLIA.

1974 • 194 citations

Calcium entry in response to maintained depolarization of squid axons

1973 • 183 citations

Stimulus‐secretion coupling processes in brain: analysis of noradrenaline and gamma‐aminobutyric acid release.

1976 • 183 citations

Potassium-induced release of amino acids from cerebral cortex and spinal cord slices of the rat

1974 • 156 citations

Potassium-stimulated γ-aminobutyric acid release from neurons and glia

1977 • 154 citations

A simple. sensitive and specific radioreceptor assay for endogenous GABA in brain tissue

1976 • 153 citations

Increasing intracellular sodium triggers calcium release from bound pools

1976 • 151 citations

SYNTHESIS AND RELEASE OF [¹⁴C]ACETYLCH0LINE IN SYNAPTOSOMES

1971 • 148 citations

Glial contamination of synaptosomal fractions

1976 • 146 citations

EFFECT OF IONS ON STIMULUS-INDUCED RELEASE OF AMINO ACIDS FROM MAMMALIAN BRAIN SLICES

1969 • 141 citations

DEPOLARIZING STIMULI AND THE RELEASE OF PHYSIOLOGICALLY ACTIVE AMINO ACIDS FROM SUSPENSIONS OF MAMMALIAN SYNAPTOSOMES

1973 • 141 citations

Coupling in secondary transport Effect of electrical potentials on the kinetics of ion linked co-transport

1976 • 127 citations

The effect of drugs on the release of norepinephrine-H from central nervous system tissued by electrical stimulation in vitro.

1967 • 126 citations

Subcellular fractionation of cultured glial cells

1971 • 125 citations

RELEASE AND EXCHANGE STUDIES RELATING TO THE SYNAPTOSOMAL UPTAKE OF GABA

1975 • 119 citations

Principles of Competitive Binding Assays (Saturation Analyses). I. Equilibrium Techniques

1973 • 114 citations

A carrier-mediated transfer model for the accumulation of 14C γ-aminobutyric acid by subcellular brain particles

1965 • 110 citations

Release of acetylcholine from hippocampal slices by potassium depolarization: dependence on high affinity choline uptake

1974 • 106 citations

Stimulus-Coupled Secretion of γ-Aminobutyric Acid from Rat Brain Synaptosomes

1973 • 103 citations

The specific effect of potassium on transmitter release by motor nerve terminals and its inhibition by calcium

1973 • 102 citations

Influence of membrane potential on the sodium-dependent uptake of gamma-aminobutyric acid by presynaptic nerve terminals: Experimental observations and theoretical considerations

1976 • 98 citations

CALCIUM‐DEPENDENT RELEASE OF EXOGENOUSLY LOADED γ‐AMINO‐[U‐¹⁴C]BUTYRATE FROM SYNAPTOSOMES: TIME COURSE OF STIMULATION BY POTASSIUM, VERATRIDINE, AND THE CALCIUM IONOPHORE, A23187

1976 • 90 citations

Differential Labeling of Glial Cells and GABA-inhibitory Interneurons and Nerve Terminals following the Microinjection of [ -3H]Alanine, [3H]DABA and [3H]GABA into Single Folia of the Cerebellum

1976 • 89 citations

DEMONSTRATION OF ACETYLCHOLINE RELEASE BY MEASURING EFFLUX OF LABELLED CHOLINE FROM CEREBRAL CORTICAL SLICES

1972 • 89 citations

Possible relationships between extracellular potassium activity and presynaptic inhibition in the spinal cord of the cat

1974 • 80 citations

FACTORS INFLUENCING THE EFFLUX OF [³H]GAMMAAMINOBUTYRIC ACID FROM SATELLITE GLIAL CELLS IN RAT SENSORY GANGLIA

1975 • 78 citations

RELATIVE IMPORTANCE OF CHOLINE TRANSPORT TO SPONTANEOUS AND POTASSIUM DEPOLARIZED RELEASE OF ACh

1975 • 73 citations

Photodetachment of Electrons from Major Negative Ions in the Lower D Region

1972 • 71 citations

Some effects of ionophore A23187 on energy utilization and the distribution of cations and anions in mitochondria

1976 • 68 citations

Potassium, sustained focal potential shifts, and dorsal root potentials of the mammalian spinal cord

1974 • 65 citations

Extracellular Accumulation of K⁺ Evoked by Activity of Primary Afferent Fibers in the Cuneate Nucleus and Dorsal Horn of Cats

1974 • 65 citations

Synaptosomes and cell separation

1976 • 61 citations

SYNAPSES AND SYNAPTOSOMES: MORPHOLOGICAL ASPECTS

1976 • 61 citations

The release of [3H]gamma-aminobutyric acid and neurophysin from the isolated rat posterior pituitary

1975 • 51 citations

Net uptake of gamma-aminobutyric acid by a high affinity synaptosomal transport system.

1977 • 47 citations

Functional assessment of GABA uptake or exchange by synaptosomal fractions

1976 • 43 citations

Selective release of newly synthesised and newly captured GABA from synaptosomes by potassium depolarisation

1975 • 41 citations

Potassium-evoked release of taurine from synaptosomal fractions of rat cerebral cortex

1976 • 41 citations

The effect of synaptic activation on the extracellular potassium concentration in the hippocampal dentate area, in vitro

1976 • 39 citations

RELEASE OF [³H]GABA FROM RAT CORTICAL SLICES: NEURONAL VS GLIAL ORIGIN

1976 • 35 citations

Methods in brain research

1976 • 34 citations

Uptake and metabolism of exogenous γ-aminobutyric acid by subcellular particles in a sodium-containing medium

1965 • 29 citations

γ‐Aminobutyric Acid Release from Neurons and Glia

1976 • 21 citations

Stimulus secretion coupling in vitro: A rapid perfusion apparatus for monitoring efflux of transmitter substances from tissue samples

1975 • 20 citations

Decrease of uptake and exchange of neurotransmitter amino acids after depletion of their synaptosomal pools

1976 • 20 citations

ON THE FUNCTIONAL COUPLING OF NEUROTRANSMITTER UPTAKE AND RELEASE IN BRAIN

1976 • 14 citations

Rapid binding of newly accumulated noradrenaline within synaptosomes

1974 • 11 citations

Evidence that the rapid binding of newly accumulated noradrenaline within synaptosomes involves synaptic vesicles

1976 • 11 citations

Isolation of Brain Mitochondria

1974 • 6 citations