Compartmentation of Amino Acids in Brain: The GABA-Glutamine-Glutamate Cycle

Handbook of Neurochemistry

1972 • 1,374 citations

Glutamine Synthetase: Glial Localization in Brain

1977 • 1,170 citations

Handbook of Neurochemistry

1969 • 940 citations

Metabolism of amino-acids

1935 • 760 citations

Metabolism of amino-acids

1935 • 559 citations

SUBCELLULAR DISTRIBUTION OF THE ENZYMES OF THE GLUTAMIC ACID, GLUTAMINE AND γ‐AMINOBUTYRIC ACID CYCLES IN RAT BRAIN*

1965 • 539 citations

A simulation study of brain compartments. Metabolism of glutamate and related substances in mouse brain

1971 • 406 citations

THE CEREBRAL AND PERIPHERAL UPTAKE OF AMMONIA IN LIVER DISEASE WITH AN HYPOTHESIS FOR THE MECHANISM OF HEPATIC COMA 12

1955 • 389 citations

Metabolic Compartmentation in the Brain

1973 • 387 citations

Metabolic Compartments in Vivo

1962 • 317 citations

The operation of the γ-aminobutyrate bypath of the tricarboxylic acid cycle in brain tissue in vitro

1970 • 306 citations

Metabolic Compartmentation and Neurotransmission

1975 • 301 citations

AMINO ACID AND PROTEIN METABOLISM‐VI CEREBRAL COMPARTMENTS OF GLUTAMIC ACID METABOLISM

1961 • 295 citations

The acute action of ammonia on rat brain metabolism in vivo

1973 • 243 citations

Compartmentation of Amino Acid Metabolism

1969 • 209 citations

On glutaminase activity in mammalian synaptosomes

1976 • 204 citations

Compartmentation of glutamate metabolism in brain. Evidence for the existence of two different tricarboxylic acid cycles in brain

1969 • 193 citations

METABOLISM OF AMINO ACIDS AND AMMONIA IN RAT BRAIN CORTEX SLICES IN VITRO: A POSSIBLE ROLE OF AMMONIA IN BRAIN FUNCTION

1975 • 185 citations

Studies on brain metabolism

1936 • 181 citations

PRECURSORS IN VIVO OF GLUTAMATE, ASPARTATE AND THEIR DERIVATIVES OF RAT BRAIN

1966 • 177 citations

SIGNIFICANCE OF GLUTAMIC ACID FOR THE METABOLISM OF NERVOUS TISSUE

1950 • 173 citations

Elevation of γ-aminobutyric acid in brain with amino-oxyacetic acid and susceptibility to convulsive seizures in mice: A quantitative re-evaluation

1966 • 166 citations

Hepatic Encephalopathy: Current Status

1974 • 144 citations

QUANTITATIVE ASPECTS OF CO₂ FIXATION IN MAMMALIAN BRAIN IN VIVO*

1964 • 139 citations

Cerebral Effects of Acute Ammonia Intoxication II. The Effect upon Energy Metabolism

1971 • 131 citations

Some Metabolic Studies of -Aminobutyric Acid.

1958 • 129 citations

INTRACELLULAR LOCALIZATION OF GLUTAMATE DECARBOXYLASE, γ‐AMINOBUTYRATE TRANSAMINASE AND SOME OTHER ENZYMES IN BRAIN TISSUE

1965 • 123 citations

A Simulation Study of the Metabolism and Compartmentation in Brain of Glutamate, Aspartate, the Krebs Cycle, and Related Metabolites

1966 • 111 citations

A Model of Glutamate Metabolism in Brain: A Biochemical Analysis of a Heterogeneous Structure

1975 • 100 citations

The effect of aminooxyacetic acid on the metabolism of γ-aminobutyric acid in brain

1966 • 79 citations

GLUTAMINE UPTAKE AND METABOLISM BY THE ISOLATED TOAD BRAIN: EVIDENCE PERTAINING TO ITS PROPOSED ROLE AS A TRANSMITTER PRECURSOR

1977 • 78 citations

Biochemistry and Neurological Disease

1977 • 71 citations

Glutamate and Glutamine

1970 • 71 citations

On the contribution of the tricarboxylic acid cycle to the synthesis of glutamate, glutamine and aspartate in brain

1966 • 55 citations

Ammonia and Brain Glutamine: Inhibition of Glutamine Degradation by Ammonia

1975 • 48 citations

Subcellular localization of γ-aminobutyrate transaminase and glutamate dehydrogenase in adult rat brain. Evidence for at least two small glutamate compartments in brain

1975 • 45 citations

Ammonia metabolism in the brain

1969 • 30 citations

Metabolism of Amino Acids and Related Substances

1936 • 27 citations

Electron cytochemical localization of gamma-aminobutyric acid catabolism in rat cerebellar cortex

1976 • 21 citations

Biochemistry and Neurological Disease

1978 • 13 citations

The Formation of Glutamine in Mouse Brain: Effect of Amino-oxyacetic Acid and Ammonia

1975 • 6 citations