The DNA binding specificity of the bipartite POU domain and its subdomains.

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

EUKARYOTIC TRANSCRIPTIONAL REGULATORY PROTEINS

1989 • 1,299 citations

The structure and function of the homeodomain

1989 • 1,007 citations

A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype

1988 • 998 citations

Crystal structure of an engrailed homeodomain-DNA complex at 2.8 Å resolution: A framework for understanding homeodomain-DNA interactions

1990 • 996 citations

The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein

1988 • 771 citations

The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products.

1988 • 750 citations

A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes

1986 • 740 citations

Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeo-and a Cys–His domain

1990 • 684 citations

The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.

1988 • 670 citations

Correct transcription of an immunoglobulin κ gene requires an upstream fragment containing conserved sequence elements

1984 • 669 citations

A structural taxonomy of DNA-binding domains

1991 • 615 citations

Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-II

1990 • 550 citations

Crystal structure of a MATα2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions

1991 • 538 citations

The sequence specificity of homeodomain-DNA interaction

1988 • 501 citations

A cloned octamer transcription factor stimulates transcription from lymphoid–specific promoters in non–B cells

1988 • 494 citations

The liver-specific transcription factor LF-B1 contains a highly diverged homeobox DNA binding domain

1989 • 490 citations

POU-domain transcription factors: pou-er-ful developmental regulators.

1991 • 461 citations

Protein-DNA contacts in the structure of a homeodomain-DNA complex determined by nuclear magnetic resonance spectroscopy in solution.

1990 • 460 citations

The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains.

1988 • 429 citations

The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1—Pit-1 interactions

1990 • 403 citations

A human lymphoid- specific transcription factor that activates immunoglobulin genes is a homoeobox protein

1988 • 399 citations

Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation

1988 • 377 citations

Octamania: The POU factors in murine development

1991 • 373 citations

The paired box encodes a second DNA-binding domain in the paired homeo domain protein.

1991 • 349 citations

A sensitive method for the determination of protein-DNA binding specificities

1990 • 346 citations

The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors

1988 • 334 citations

Defining the Sequence Specificity of DNA-Binding Proteins by Selecting Binding Sites from Random-Sequence Oligonucleotides: Analysis of Yeast GCN4 Protein

1989 • 333 citations

The POU domain is a bipartite DNA-binding structure

1988 • 304 citations

DNA binding specificity of homeodomains

1991 • 300 citations

The molecular basis of the undulated/Pax-1 mutation

1991 • 273 citations

HNF-1 shares three sequence motifs with the POU domain proteins and is identical to LF-B1 and APF.

1990 • 264 citations

An enhancer-like sequence within the Xenopus U2 gene promoter facilitates the formation of stable transcription complexes

1985 • 250 citations

A human protein specific for the immunoglobulin octamer DNA motif contains a functional homeobox domain

1988 • 234 citations

Regulation of transcription and cell identity by POU domain proteins

1991 • 233 citations

Target Detection Assay (TDA): a versatile procedure to determine DNA blinding sites as demonstrated on SP1 protein

1990 • 229 citations

Interactions of the Oct-1 POU subdomains with specific DNA sequences and with the HSV alpha-trans-activator protein.

1990 • 227 citations

Characterization of a Cofactor That Regulates Dimerization of a Mammalian Homeodomain Protein

1991 • 225 citations

Isolation and sequence-specific DNA binding of the Antennapedia homeodomain.

1988 • 221 citations

DNA binding properties of the purified Antennapedia homeodomain.

1990 • 193 citations

OBP100 binds remarkably degenerate octamer motifs through specific interactions with flanking sequences.

1988 • 184 citations

Optimal DNA sequence recognition by the Ultrabithorax homeodomain of Drosophila.

1991 • 184 citations

Kinetics and mechanism in the reaction of gene regulatory proteins with DNA

1984 • 181 citations

A myosin-like dimerization helix and an extra-large homeodomain are essential elements of the tripartite DNA binding structure of LFB1

1990 • 157 citations

The DNA binding domain (POU domain) of transcription factor oct-1 suffices for stimulation of DNA replication.

1990 • 149 citations

The interaction with DNA of wild-type and mutant fushi tarazu homeodomains.

1990 • 142 citations

Octamer transcription factors bind to two different sequence motifs of the immunoglobulin heavy chain promoter.

1989 • 139 citations

The oct-1 homeo domain contacts only part of the octamer sequence and full oct-1 DNA-binding activity requires the POU-specific domain.

1990 • 135 citations

The Oct-2 protein binds cooperatively to adjacent octamer sites.

1989 • 132 citations

Functional cooperativity between protein molecules bound at two distinct sequence elements of the immunoglobulin heavy-chain promoter

1989 • 128 citations

The octamer binding factor Oct6: cDNA cloning and expression in early embryonic cells

1990 • 124 citations

POU proteins bend DNA via the POU-specific domain.

1991 • 111 citations

Transcription factors NFI and NFIII/oct-1 function independently, employing different mechanisms to enhance adenovirus DNA replication

1990 • 111 citations

Segments of the POU domain influence one another's DNA-binding specificity.

1992 • 99 citations

Growth hormone gene regulation: a paradigm for cell-type-specific gene activation

1990 • 93 citations

DNA-binding specificity of the fushi tarazu homeodomain.

1991 • 90 citations

A fungal mating type protein that regulates sexual and asexual development contains a POU-related domain.

1992 • 88 citations

The Oct-1 POU domain mediates interactions between Oct-1 and other POU proteins.

1992 • 84 citations

Interaction between the octamer-binding protein nuclear factor III and the adenovirus origin of DNA replication

1988 • 51 citations

Biochemical characterization of the Oct-2 POU domain with implications for bipartite DNA recognition

1992 • 40 citations

DNA-Binding Specificity of the fushi tarazu Homeodomain†

1991 • 40 citations

The Oct-1 POU Domain Mediates Interactions between Oct-1 and Other POU Proteins

1992 • 35 citations

Segments of the POU Domain Influence One Another’s DNA-Binding Specificity

1992 • 30 citations