A novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

DNA cloning : a practical approach

1985 • 2,302 citations

Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain

1987 • 1,640 citations

The structure and function of the homeodomain

1989 • 1,007 citations

The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products.

1988 • 750 citations

A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes

1986 • 740 citations

Differential transcriptional activation by Oct-1 and Oct-2: Interdependent activation domains induce Oct-2 phosphorylation

1990 • 696 citations

Protein-Binding Sites in Ig Gene Enhancers Determine Transcriptional Activity and Inducibility

1987 • 619 citations

The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer.

1990 • 584 citations

Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene

1987 • 516 citations

A cloned octamer transcription factor stimulates transcription from lymphoid–specific promoters in non–B cells

1988 • 494 citations

POU-domain transcription factors: pou-er-ful developmental regulators.

1991 • 461 citations

The Oct-1 homoeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16

1989 • 434 citations

An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity

1987 • 398 citations

Identification and purification of a human lymphoid-specific octamer-binding protein (OTF-2) that activates transcription of an immunoglobulin promoter in vitro

1987 • 386 citations

A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins.

1988 • 381 citations

Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation

1988 • 377 citations

Octamania: The POU factors in murine development

1991 • 373 citations

What determines the specificity of action of Drosophila homeodomain proteins?

1990 • 357 citations

Activation of class II gene transcription by regulatory factors is potentiated by a novel activity

1991 • 318 citations

Interaction of cell-type-specific nuclear proteins with immunoglobulin VH promoter region sequences

1986 • 298 citations

Immunoglobulin Gene Transcription

1991 • 294 citations

Cell type-specificity elements of the immunoglobulin heavy chain gene enhancer.

1987 • 255 citations

OVEC, a versatile system to study transcription in mammalian cells and cell-free extracts

1987 • 255 citations

Cell-cycle regulation of a human histone H2b gene is mediated by the H2b subtype-specific consensus element.

1988 • 234 citations

Regulation of transcription and cell identity by POU domain proteins

1991 • 233 citations

A nexus between Oct-4 and E1 A: Implications for gene regulation in embryonic stem cells

1991 • 188 citations

Oct-1 and Oct-2 potentiate functional interactions of a transcription factor with the proximal sequence element of small nuclear RNA genes.

1992 • 179 citations

GAL11P: A yeast mutation that potentiates the effect of weak GAL4-derived activators

1990 • 149 citations

Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cells.

1990 • 146 citations

Activation of Early Gene Expression in T Lymphocytes by Oct-1 and an Inducible Protein, OAP ⁴⁰

1991 • 144 citations

The conserved decanucleotide from the immunoglobulin heavy chain promoter induces a very high transcriptional activity in B-cells when introduced into an heterologous promoter.

1987 • 144 citations

Multiple Oct2 isoforms are generated by alternative splicing

1991 • 141 citations

The cell type-specific octamer transcription factor OTF-2 has two domains required for the activation of transcription.

1990 • 139 citations

Molecular Aspects of B-Lymphocyte Activation

1987 • 136 citations

Octamer-binding proteins from B or HeLa cells stimulate transcription of the immunoglobulin heavy-chain promoter in vitro.

1988 • 132 citations

Independently evolving chicken histone H2B genes: identification of a ubiquitous H2B-specific 5′ element

1982 • 131 citations

Functional cooperativity between protein molecules bound at two distinct sequence elements of the immunoglobulin heavy-chain promoter

1989 • 128 citations

Structure and expression of the mouse Oct2a and Oct2b, two differentially spliced products of the same gene

1990 • 125 citations

Activation of octamer-containing promoters by either octamer-binding transcription factor 1 (OTF-1) or OTF-2 and requirement of an additional B-cell-specific component for optimal transcription of immunoglobulin promoters.

1990 • 117 citations

‘Snurpogenesis’: The transcription and assembly of U snRNP components

1989 • 103 citations

Complex pattern of immunoglobulin mu gene expression in normal and transgenic mice: nonoverlapping regulatory sequences govern distinct tissue specificities.

1991 • 99 citations

Cell-type-specific transcription of an immunoglobulin kappa light chain gene in vitro.

1986 • 96 citations

High expression of functional adenovirus DNA polymerase and precursor terminal protein using recombinant vaccinia virus

1988 • 94 citations

Recombinant 43-kDa USF binds to DNA and activates transcription in a manner indistinguishable from that of natural 43/44-kDa USF.

1991 • 88 citations

Ecdysterone Receptor Is a Sequence-Specific Transcription Factor Involved in the Developmental Regulation of Heat Shock Genes

1991 • 87 citations

A bipartite DNA binding domain composed of direct repeats in the TATA box binding factor TFIID.

1992 • 60 citations

Structure and function of the homeodomain

1989 • 58 citations

The pEMBL family of single stranded vectors

1984 • 58 citations

Ecdysterone receptor is a sequence-specific transcription factor involved in the developmental regulation of heat shock genes.

1991 • 55 citations

The ubiquitous octamer-binding protein(s) is sufficient for transcription of immunoglobulin genes.

1990 • 44 citations

Octamer-binding proteins in diverse hemopoietic cells.

1990 • 35 citations

Octamania: The POU factors in murine development

1991 • 32 citations