Type I Collagen-Mediated Changes in Gene Expression and Function of Prostate Cancer Cells

Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring

1999 • 11,586 citations

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

2000 • 9,712 citations

Integrin Signaling

1999 • 3,705 citations

Mechanisms of Bone Metastasis

2004 • 2,680 citations

Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays

1998 • 1,781 citations

CLINICAL CANCER RESEARCH

1956 • 1,729 citations

Delineation of prognostic biomarkers in prostate cancer

2001 • 1,694 citations

Meta-analysis of microarrays: interstudy validation of gene expression profiles reveals pathway dysregulation in prostate cancer.

2002 • 656 citations

Survey of gene amplifications during prostate cancer progression by high-throughout fluorescence in situ hybridization on tissue microarrays.

1999 • 606 citations

MAPK Pathways Activate and Phosphorylate the Osteoblast-specific Transcription Factor, Cbfa1

2000 • 543 citations

Cancer and Bone*

1998 • 491 citations

Identifying distinct classes of bladder carcinoma using microarrays

2002 • 487 citations

The program of androgen-responsive genes in neoplastic prostate epithelium

2002 • 473 citations

The cell-cycle regulatory protein Cks1 is required for SCFSkp2-mediated ubiquitinylation of p27

2001 • 467 citations

TOR signalling and control of cell growth

1997 • 458 citations

Cellular gene expression altered by human cytomegalovirus: Global monitoring with oligonucleotide arrays

1998 • 445 citations

Osteomimetic properties of prostate cancer cells: A hypothesis supporting the predilection of prostate cancer metastasis and growth in the bone environment

1999 • 428 citations

Mechanisms of bone metastasis

1997 • 416 citations

The influence of the microenvironment on the malignant phenotype

2000 • 398 citations

Integrins in Development

2002 • 397 citations

Role of the α2-Integrin in Osteoblast-specific Gene Expression and Activation of the Osf2 Transcription Factor

1998 • 373 citations

Hormone Therapy Failure in Human Prostate Cancer: Analysis by Complementary DNA and Tissue Microarrays

1999 • 356 citations

Integrin alpha 2 beta 1 is upregulated in fibroblasts and highly aggressive melanoma cells in three-dimensional collagen lattices and mediates the reorganization of collagen I fibrils.

1991 • 354 citations

The role of high rates of glycolysis and glutamine utilization in rapidly dividing cells

1985 • 350 citations

Identification of differentially expressed genes in human prostate cancer using subtraction and microarray.

2000 • 339 citations

Gene expression profiling: monitoring transcription and translation products using DNA microarrays and proteomics

2000 • 321 citations

cDNA microarrays detect activation of a myogenic transcription program by thePAX3-FKHRfusion oncogene

1999 • 313 citations

Differentiation and Transforming Growth Factor-β Receptor Down-regulation by Collagen-α2β1 Integrin Interaction Is Mediated by Focal Adhesion Kinase and Its Downstream Signals in Murine Osteoblastic Cells

1997 • 289 citations

Osteopontin: possible role in prostate cancer progression.

1999 • 266 citations

Differential gene expression profiles of scirrhous gastric cancer cells with high metastatic potential to peritoneum or lymph nodes.

2001 • 248 citations

Preferential Adhesion of Prostate Cancer Cells to a Human Bone Marrow Endothelial Cell Line

1998 • 235 citations

Expression of syndecan regulates human myeloma plasma cell adhesion to type I collagen

1993 • 230 citations

Granulins: the structure and function of an emerging family of growth factors

1998 • 230 citations

Differential gene expression profiling in human brain tumors

2001 • 218 citations

Osteonectin promotes prostate cancer cell migration and invasion: a possible mechanism for metastasis to bone.

1999 • 216 citations

CD44 and the adhesion of neoplastic cells.

1997 • 206 citations

The ezrin protein family: membrane-cytoskeleton interactions and disease associations

1997 • 205 citations

Organ-preference of metastasis

1990 • 197 citations

Biological activities and signaling pathways of the granulin/epithelin precursor.

1999 • 179 citations

Expression profiling in cancer using cDNA microarrays

1999 • 176 citations

Progranulin gene expression regulates epithelial cell growth and promotes tumor growth in vivo.

1999 • 170 citations

PDZ domain proteins: Scaffolds for signaling complexes

1997 • 161 citations

Dysregulated expression of androgen-responsive and nonresponsive genes in the androgen-independent prostate cancer xenograft model CWR22-R1.

2000 • 154 citations

Molecules in focus The CD44 protein family

1998 • 154 citations

High Levels of Ezrin Expressed by Human Pancreatic Adenocarcinoma Cell Lines with High Metastatic Potential

1999 • 145 citations

Cancer and Bone

1998 • 143 citations

Organ preference of metastasis. The role of organ-specifically modulated endothelial cells.

1988 • 137 citations

Tissue architecture and breast cancer: the role of extracellular matrix and steroid hormones.

2000 • 133 citations

Mitogenic Signaling by Ret/ptc2 Requires Association with Enigma via a LIM Domain

1996 • 123 citations

Differentially Expressed Genes in Two LNCaP Prostate Cancer Cell Lines Reflecting Changes during Prostate Cancer Progression

2000 • 113 citations

Specificity of LIM Domain Interactions with Receptor Tyrosine Kinases

1996 • 108 citations

Cell-adhesion-dependent influences on genomic instability and carcinogenesis

1998 • 101 citations

Adhesion-mediated signaling in the regulation of mammary epithelial cell survival.

1999 • 100 citations

Rat prostate adenocarcinoma cells disseminate to bone and adhere preferentially to bone marrow-derived endothelial cells.

1992 • 86 citations

Extracellular Matrix Selectively Modulates the Response of Mammary Epithelial Cells to Different Soluble Signaling Ligands

1999 • 81 citations

Genomics and array technology

1999 • 81 citations

Gene expression profiling with oligonucleotide microarrays distinguishes World Health Organization grade of oligodendrogliomas.

2001 • 78 citations

Bone cell matrix promotes the adhesion of human prostatic carcinoma cells via the α2β1 integrin

1996 • 77 citations

Synthetic peptide containing Arg-Gly-Asp inhibits bone formation and resorption in a mineralizing organ culture system of fetal rat parietal bones

1994 • 77 citations

Microarray-based expression profiling in prostate tumors.

2000 • 74 citations

Type I collagen-mediated proliferation of PC3 prostate carcinoma cell line: implications for enhanced growth in the bone microenvironment

2001 • 72 citations

The enigma of LIM domains

1995 • 72 citations

Application of metabolic-control logic to fuel utilization and its significance in tumor cells

1991 • 68 citations

Gene expression profiles at different stages of human esophageal squamous cell carcinoma

2003 • 67 citations

Altered Expression of RET Proto-oncogene Product in Prostatic Intraepithelial Neoplasia and Prostate Cancer

1998 • 66 citations

RGD-recognizing integrins mediate interactions of human prostate carcinoma cells with endothelial cells in vitro

1999 • 62 citations

Transforming growth factor beta upregulates the integrin-mediated adhesion of human prostatic carcinoma cells to type I collagen.

1996 • 53 citations

Expression of CD44 isoforms in human prostate tumor cell lines

1996 • 49 citations

Calcium signals in prostate cancer cells: specific activation by bone-matrix proteins

2000 • 48 citations

Production and response of human prostate cancer cell lines to granulocyte macrophage‐colony stimulating factor

1994 • 43 citations

How Tumor Cells Make Use of CD44

1998 • 43 citations

Metabolic characteristics of different malignant cancer cell lines.

1998 • 37 citations

Gene expression analysis of human thymoma correlates with tumor stage

2002 • 37 citations

Effect of bone proteins on human prostate cancer cell lines in vitro

1998 • 33 citations

Microarray analysis in prostate cancer research

2002 • 30 citations

Laminin-5-mediated gene expression in human prostate carcinoma cells

2001 • 24 citations

Cytokine regulation of ezrin expression in the human colon cancer cell line HT29.

1996 • 15 citations

[Growth factors and prostatic tumors].

1997 • 12 citations

Laboratory Investigations

1988 • 11 citations

Does the Oxidative/Glycolytic Ratio Determine Proliferation or Death in Immune Recognition?

1999 • 7 citations