Organ-preference of metastasis

THE DISTRIBUTION OF SECONDARY GROWTHS IN CANCER OF THE BREAST.

1889 • 4,920 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Models for the Specific Adhesion of Cells to Cells

1978 • 4,159 citations

Endothelial Leukocyte Adhesion Molecule 1: an Inducible Receptor for Neutrophils Related to Complement Regulatory Proteins and Lectins

1989 • 2,045 citations

VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site

1990 • 1,836 citations

Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes

1989 • 1,715 citations

Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1)

1987 • 1,712 citations

A cell-surface molecule involved in organ-specific homing of lymphocytes

1983 • 1,515 citations

How does the extracellular matrix direct gene expression?

1982 • 1,475 citations

Neutrophil Mac-1 and MEL-14 Adhesion Proteins Inversely Regulated by Chemotactic Factors

1989 • 1,135 citations

Slow viscous motion of a sphere parallel to a plane wall—II Couette flow

1967 • 1,105 citations

Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells.

1988 • 988 citations

Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families

1988 • 967 citations

A heparin-binding angiogenic protein--basic fibroblast growth factor--is stored within basement membrane.

1988 • 892 citations

Leukocyte-endothelial interactions

1985 • 834 citations

Long-term culture of capillary endothelial cells.

1979 • 780 citations

Apparent viscosity and cortical tension of blood granulocytes determined by micropipet aspiration

1989 • 771 citations

Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells.

1986 • 748 citations

A tissue-specific endothelial cell molecule involved in lymphocyte homing

1988 • 725 citations

BIOCHEMICAL INTERACTIONS OF TUMOR CELLS WITH THE BASEMENT MEMBRANE

1986 • 693 citations

Lymphocyte homing into lymph nodes: in vitro demonstration of the selective affinity of recirculating lymphocytes for high-endothelial venules.

1976 • 680 citations

An Inducible Endothelial Cell Surface Glycoprotein Mediates Melanoma Adhesion

1989 • 659 citations

Adhesion molecules controlling lymphocyte migration

1989 • 654 citations

Immunohistologic and functional characterization of a vascular addressin involved in lymphocyte homing into peripheral lymph nodes.

1988 • 639 citations

Leukocyte-endothelial interactions

1985 • 635 citations

Capillary endothelial cell cultures: phenotypic modulation by matrix components.

1983 • 611 citations

Phenotypic modulation of endothelial cells by transforming growth factor-beta depends upon the composition and organization of the extracellular matrix.

1988 • 571 citations

Organ specificity of tumor metastasis: role of preferential adhesion, invasion and growth of malignant cells at specific secondary sites

1988 • 508 citations

Identification of a murine Peyer's patch—specific lymphocyte homing receptor as an integrin molecule with an α chain homologous to human VLA-4α

1989 • 495 citations

How does extracellular matrix control capillary morphogenesis?

1989 • 466 citations

Passive mechanical properties of human leukocytes

1981 • 414 citations

Cancer metastasis: tumor cell and host organ properties important in metastasis to specific secondary sites

1988 • 405 citations

Connective tissue biomatrix: its isolation and utilization for long-term cultures of normal rat hepatocytes.

1980 • 395 citations

Differentiation of axon-related Schwann cells in vitro. I. Ascorbic acid regulates basal lamina assembly and myelin formation.

1987 • 393 citations

Effect of venous shear stress on CD18-mediated neutrophil adhesion to cultured endothelium

1990 • 370 citations

Cell biology of endothelial cells

1987 • 356 citations

Heparan Sulfate Degradation: Relation to Tumor Invasive and Metastatic Properties of Mouse B16 Melanoma Sublines

1983 • 350 citations

The Cellular Basis of Site-Specific Tumor Metastasis

1990 • 349 citations

Organ specificity of lymphocyte migration: mediation by highly selective lymphocyte interaction with organ‐specific determinants on high endothelial venules

1980 • 347 citations

Homing Receptors and Vascular Addressins: Cell Adhesion Molecules that Direct Lymphocyte Traffic

1989 • 332 citations

Heparanases and tumor metastasis

1988 • 303 citations

Cancer Metastasis: Experimental Approaches, Theoretical Concepts, and Impacts for Treatment Strategies

1985 • 301 citations

Cortical shell-liquid core model for passive flow of liquid-like spherical cells into micropipets

1989 • 279 citations

Endothelial cell proliferation during angiogenesis. In vitro modulation by basement membrane components.

1986 • 277 citations

Metabolism of receptor-bound and matrix-bound basic fibroblast growth factor by bovine capillary endothelial cells.

1988 • 276 citations

?Seed and soil? revisited: mechanisms of site-specific metastasis

1982 • 276 citations

Differentiated microdomains on the luminal surface of the capillary endothelium. I. Preferential distribution of anionic sites.

1981 • 267 citations

A dynamical model for receptor-mediated cell adhesion to surfaces

1987 • 263 citations

Extracellular matrix promotes mammary epithelial growth and differentiation in vitro.

1982 • 262 citations

Lymphoma cell-mediated degradation of sulfated proteoglycans in the subendothelial extracellular matrix: relationship to tumor cell metastasis.

1983 • 259 citations

Specificity of adhesion between murine tumor cells and capillary endothelium: an in vitro correlate of preferential metastasis in vivo.

1987 • 250 citations

Involvement of Sialic Acid on Endothelial Cells in Organ-Specific Lymphocyte Recirculation

1985 • 236 citations

Primary culture of capillary endothelium from rat brain

1981 • 234 citations

Special Report The Complexity of Endothelial Cells: A Review

1989 • 233 citations

American Association of Pathologists president's address. New roles for the endothelium in inflammation and immunity.

1987 • 232 citations

Possible role for cell-surface carbohydrate-binding molecules in lymphocyte recirculation.

1983 • 232 citations

Lymphocyte Homing

1989 • 227 citations

Lymphocyte Adherence to High Endothelial Venules: Characterization of a Modified in Vitro Assay, and Examination of the Binding of Syngeneic and Allogeneic Lymphocyte Populations

1979 • 215 citations

Metastatic tumor cells adhere preferentially to the extracellular matrix underlying vascular endothelial cells

1980 • 212 citations

Ulex europaeus I Lectin as a Marker for Tumors Derived from Endothelial Cells

1983 • 211 citations

Differentiation of axon-related Schwann cells in vitro: II. Control of myelin formation by basal lamina

1989 • 200 citations

Metastatic tumor cell attachment and invasion assay utilizing vascular endothelial cell monolayers.

1982 • 187 citations

Vascular endothelium-leukocyte interaction; sticking shear force in venules.

1975 • 174 citations

Bidirectional control of membrane expression and/or activation of the tumor cell IRGpIIb/IIIa receptor and tumor cell adhesion by lipoxygenase products of arachidonic acid and linoleic acid.

1989 • 173 citations

Warner-Lambert/Parke-Davis Award lecture. Cellular and molecular mechanisms that direct leukocyte traffic.

1990 • 170 citations

Differentiated microdomains on the luminal surface of capillary endothelium: distribution of lectin receptors.

1982 • 166 citations

Lectin binding sites in kidney. A comparative study of 14 animal species.

1983 • 161 citations

Principles of metastasis

1985 • 160 citations

Differential expression of cell surface glycoproteins on various organ‐derived microvascular endothelia and endothelial cell cultures

1988 • 155 citations

Endothelial Cell Phenotypic Diversity: In Situ Demonstration of Immunologic and Enzymatic Heterogeneity that Correlates with Specific Morphologic Subtypes

1987 • 149 citations

Tumor invasion: A consequence of destructive and compositional matrix alterations

1988 • 146 citations

Interactions between cancer cells and the microvasculature: a rate-regulator for metastasis

1989 • 144 citations

Heterogeneity of mouse vascular endothelium. In vitro studies of lymphatic, large blood vessel and microvascular endothelial cells.

1987 • 143 citations

ENDOTHELIUM: A DISTRIBUTED ORGAN OF DIVERSE CAPABILITIES

1982 • 139 citations

Tumor cell-endothelial interactions. Increased adhesion of human melanoma cells to activated vascular endothelium.

1988 • 137 citations

Organ preference of metastasis. The role of organ-specifically modulated endothelial cells.

1988 • 137 citations

Enhanced tumor cell adhesion to the subendothelial matrix resulting from 12(S)‐HETE‐induced endothelial cell retraction

1989 • 122 citations

The formation of fenestrations and channels by capillary endothelium in vitro.

1985 • 117 citations

Phenotypic diversity in cultured cerebral microvascular endothelial cells

1988 • 114 citations

High endothelial venule binding as a predictor of the dissemination of passaged murine lymphomas.

1987 • 111 citations

Microvascular endothelium and pericytes: High yield, low passage cultures

1986 • 107 citations

Differential adhesion of tumor cells to capillary endothelial cells in vitro.

1984 • 106 citations

Aortic endothelial cell migration. I. Matrix requirements and composition.

1982 • 103 citations

Intravenously injected sialidase inactivates attachment sites for lymphocytes on high endothelial venules.

1989 • 95 citations

Organ-related differences in binding of Dolichos biflorus agglutinin to vascular endothelium

1983 • 90 citations

Endothelialization of embolized tumor cells during metastasis formation

1988 • 87 citations

MRC OX-43: a monoclonal antibody which reacts with all vascular endothelium in the rat except that of brain capillaries.

1986 • 81 citations

Regulation of growth and differentiation of a rat hepatoma cell line by the synergistic interactions of hormones and collagenous substrata.

1983 • 79 citations

Extracellular matrix specificity for the differentiation of capillary endothelial cells

1988 • 77 citations

Adhesion of neutrophil leucocytes under conditions of flow

1984 • 74 citations

Homing Receptors and Metastasis

1988 • 71 citations

THE RELATIONSHIP BETWEEN THE DISSEMINATION OF TUMOR CELLS AND THE DISTRIBUTION OF METASTASES.

1964 • 70 citations

Basal lamina formation by cultured microvascular endothelial cells.

1984 • 69 citations

Lymphocyte recognition of lymph node high endothelium. IV. Cell surface structures mediating entry into lymph nodes.

1982 • 69 citations

Lymphocyte recognition of lymph node high endothelium. VI. Evidence of distinct structures mediating binding to high endothelial cells of lymph nodes and Peyer's patches.

1984 • 65 citations

BIOCHEMICALLY DIFFERENTIATED MICRODOMAINS OF THE CELL SURFACE OF CAPILLARY ENDOTHELIUM*

1982 • 65 citations

Organ specific metastasis with special reference to avian systems

1983 • 65 citations

Biomechanical interactions of cancer cells with the microvasculature during metastasis

1989 • 62 citations

Adhesive, invasive, and growth properties of selected metastatic variants of a murine large-cell lymphoma.

1989 • 61 citations

Adhesion and detachment of biological cellsin vitro

1981 • 54 citations

Patterns of tumor metastasis: organ selectivity in the spread of cancer cells.

1988 • 50 citations

Promotion of Growth of Tumour Cells in Acutely Inflamed Tissues

1974 • 48 citations

Modulation of endothelial cell surface glycoconjugate expression by organ-derived biomatrices

1991 • 47 citations

Pulmonary Inflammation Generates Chemotactic Activity for Tumor Cells and Promotes Lung Metastasis

1985 • 44 citations

Warner-Lambert/Parke-Davis Award lecture. Cellular and molecular mechanisms that direct leukocyte traffic.

1990 • 43 citations

Endothelial Cell Dysfunction

2014 • 42 citations

Gelatin-degrading type IV collagenase isolated from human small cell lung cancer.

1989 • 39 citations

REGULATION OF GROWTH AND DIFFERENTIATION OF EPITHELIAL CELLS BY HORMONES, GROWTH FACTORS, AND SUBSTRATES OF EXTRACELLULAR MATRIX*

1981 • 37 citations

Mapping of the bone marrow sinus endothelium with lectins and glycosylated ferritins: Identification of differentiated microdomains and their functional significance

1983 • 36 citations

Platelet-aggregating activities of metastasizing tumor cells. IV. Effects of cell surface modification on thrombin generation, platelet aggregation and subsequent lung colonization.

1986 • 32 citations

Interactions between lymphoid tumor cells and isolated liver endothelial cells.

1984 • 30 citations

Changes in lectin binding patterns in the developing pulmonary vasculature of the pig lung

1986 • 29 citations

A dynamical model for receptor-mediated cell adhesion to surfaces in viscous shear flow

1989 • 29 citations

Locomotion of tumor cells as an element of invasion and metastasis.

1987 • 29 citations

Organ-specific chemotactic factors present in lung extracellular matrix

1989 • 28 citations

Principles of Metastasis

1986 • 21 citations

Mapping of the rat liver endothelial membrane with lectins and glycosylated ferritins

1986 • 14 citations

Homing Receptors in Lymphocyte, Neutrophil, and Monocyte Interaction with Endothelial Cells

1990 • 8 citations

The Structure, the Function, and the Regulation

2023 • 7 citations

Role of Tumour Cell Eicosanoids and Membrane Glycoproteins IRGPIb and IRGPIIb/IIIa in Metastasis

1988 • 5 citations