The class II tumour suppressor gene H-REV107-1 is a target of interferon-regulatory factor-1 and is involved in IFNγ-induced cell death in human ovarian carcinoma cells

The Hallmarks of Cancer

2000 • 27,569 citations

Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

1997 • 4,870 citations

Cancer-epigenetics comes of age

1999 • 2,379 citations

Control of Angiogenesis in Fibroblasts by p53 Regulation of Thrombospondin-1

1994 • 1,460 citations

PIK3CA is implicated as an oncogene in ovarian cancer

1999 • 1,170 citations

Negative Regulation of Cytokine Signaling Pathways

2000 • 607 citations

Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1

1994 • 490 citations

Interferons and other regulatory cytokines

1988 • 429 citations

Deletion of IRF-1 , Mapping to Chromosome 5q31.1, in Human Leukemia and Preleukemic Myelodysplasia

1993 • 392 citations

DNA methylation and cancer

2000 • 366 citations

An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes

1997 • 364 citations

Methylation of the BRCA1 promoter region in sporadic breast and ovarian cancer: correlation with disease characteristics

1999 • 353 citations

Interferons and other regulatory cytokines

1989 • 306 citations

A genome-wide survey of RAS transformation targets

2000 • 293 citations

p53 Regulates the Expression of the Tumor Suppressor Gene Maspin

2000 • 281 citations

Expression genetics in cancer: Shifting the focus from DNA to RNA

1997 • 256 citations

Interferon-gamma in the first-line therapy of ovarian cancer: a randomized phase III trial

2000 • 235 citations

Expression of Gene rrg Is Associated with Reversion of NIH 3Tt3 Transformed by LTR-c-H- ras

1990 • 224 citations

Retinoids: present role and future potential

1999 • 219 citations

Induction of Cellular Differentiation by Retinoic Acid in vitro

1999 • 209 citations

Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-γ target genes

2000 • 200 citations

Characterization of Human Ovarian Surface Epithelial Cells Immortalized by Human Papilloma Viral Oncogenes (HPV-E6E7 ORFs)

1995 • 200 citations

Ras activation in human breast cancer

2000 • 183 citations

Identification and characterization of nucleophosmin/B23/numatrin which binds the anti-oncogenic transcription factor IRF-1 and manifests oncogenic activity

1997 • 177 citations

Identification and characterization of a retinoid-induced class II tumor suppressor/growth regulatory gene

1998 • 162 citations

Transactivation through Ets and Ap1 transcription sites determines the expression of the tumor-suppressing gene maspin.

1997 • 138 citations

An Activated ras ^N Gene: Detected in Late But Not Early Passage Human PA1 Teratocarcinoma Cells

1984 • 131 citations

Growth-inhibitory Activity and Downregulation of the Class II Tumor-suppressor Gene H-rev107 in Tumor Cell Lines and Experimental Tumors

1997 • 108 citations

Two distinct regions of deletion on the long arm of chromosome 5 in differentiated adenocarcinomas of the stomach.

1996 • 106 citations

p53 Regulates Caveolin Gene Transcription, Cell Cholesterol, and Growth by a Novel Mechanism

2000 • 102 citations

Frequent loss of BRCA1 mRNA and protein expression in sporadic ovarian cancers

2000 • 91 citations

Identification of the lysyl oxidase gene as target of the antioncogenic transcription factor, IRF-1, and its possible role in tumor suppression.

1996 • 87 citations

Functionally inactivating point mutation in the tumor-suppressorIRF-1 gene identified in human gastric cancer

1998 • 84 citations

The interferon regulatory factors and oncogenesis

2000 • 81 citations

Suppression of c-myc or fosB-induced cell transformation by the transcription factor IRF-1

1994 • 81 citations

Inducible processing of interferon regulatory factor-2.

1992 • 69 citations

Use of SMART™-Generated cDNA for Gene Expression Studies in Multiple Human Tumors

2001 • 66 citations

Transcriptional and translational downregulation of H-REV107, a class II tumour suppressor gene located on human chromosome 11q11-12

1998 • 61 citations

Retinoic acid and interferon signaling cross talk in normal and RA-resistant APL cells

1999 • 56 citations

Lack of IRF-1 expression in acute promyelocytic leukemia and in a subset of acute myeloid leukemias with del(5)(q31)

1999 • 55 citations

Cytotoxic response of ovarian cancer cell lines to IFN-γ is associated with sustained induction of IRF-1 and p21 mRNA

1999 • 53 citations

Cooperative activity between HER oncogenes and the tumor suppressor IRF-1 results in apoptosis

1999 • 43 citations

The Cell Cycle Control Element of Histone H4 Gene Transcription Is Maximally Responsive to Interferon Regulatory Factor Pairs IRF-1/IRF-3 and IRF-1/IRF-7

2001 • 37 citations

A Cell Line, ROSE 199, Derived from Normal Rat Ovarian Surface Epithelium

1985 • 36 citations

Evidence for IRF-1-dependent gene expression deficiency in interferon unresponsive HepG2 cells

1999 • 32 citations

Identification of mRNAs Regulated by Interferon-γ in Cultured Rat Astrocytes by PCR Differential Display

1995 • 26 citations

Gene expression profiling of fibroblasts resistant toward oncogene-mediated transformation reveals preferential transcription of negative growth regulators

1999 • 25 citations

Partial restoration of pre‐transformation levels of lysyl oxidase and transin mRNAs in phenotypic ras revertants

1995 • 17 citations

IRF-1-Mediated CAS Expression Enhances Interferon-γ-Induced Apoptosis of HT-29 Colon Adenocarcinoma Cells

2001 • 11 citations

Resources

2001 • 1 citations