A genome-wide survey of RAS transformation targets

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

ras oncogenes in human cancer: a review.

1989 • 5,116 citations

ras GENES

1987 • 3,818 citations

Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries.

1996 • 3,063 citations

A synthetic inhibitor of the mitogen-activated protein kinase cascade.

1995 • 2,723 citations

The Transcriptional Program in the Response of Human Fibroblasts to Serum

1999 • 1,994 citations

Gene Expression Profiles in Normal and Cancer Cells

1997 • 1,157 citations

Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

1992 • 583 citations

Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway.

1994 • 454 citations

Diverse Signaling Pathways Activated by Growth Factor Receptors Induce Broadly Overlapping, Rather Than Independent, Sets of Genes

1999 • 450 citations

Expression genetics in cancer: Shifting the focus from DNA to RNA

1997 • 256 citations

RAS pathways to cell cycle control and cell transformation

1998 • 247 citations

Aberrant function of the Ras signal transduction pathway in human breast cancer

1995 • 218 citations

The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle.

1994 • 216 citations

Increasing Complexity of Ras Signal Transduction: Involvement of Rho Family Proteins

1997 • 185 citations

A high throughput screening for rarely transcribed differentially expressed genes

1997 • 178 citations

Transformation of mammalian cells by avian myelocytomatosis virus and avian erythroblastosis virus

1979 • 166 citations

Growth-inhibitory Activity and Downregulation of the Class II Tumor-suppressor Gene H-rev107 in Tumor Cell Lines and Experimental Tumors

1997 • 108 citations

Association of the Viral Oncoprotein STP-C488 with Cellular ras

1995 • 101 citations

Expression of cloned sequences in biopsies of human colonic tissue and in colonic carcinoma cells induced to differentiate in vitro.

1987 • 101 citations

Activation of cellular genes by avian RNA tumor viruses.

1980 • 91 citations

p21 Ras as a governor of global gene expression.

1994 • 80 citations

Transcriptional and translational downregulation of H-REV107, a class II tumour suppressor gene located on human chromosome 11q11-12

1998 • 61 citations

Characterization of transformation related genes in oral cancer cells

1998 • 60 citations

Activation of the ras-mitogen-activated protein kinase pathway and phosphorylation of ets-2 at position threonine 72 in human ovarian cancer cell lines.

1998 • 58 citations

Control of Ha-ras-mediated mammalian cell transformation by Escherichia coli regulatory elements.

1992 • 51 citations

Mitotic and post mitotic consequences of genomic instability induced by oncogenic Ha-Ras

1995 • 45 citations

A Cell Line, ROSE 199, Derived from Normal Rat Ovarian Surface Epithelium

1985 • 36 citations

Suppression and re‐expression of transformed phenotype in hybrids of HA‐ras‐1 ‐transformed rat‐1 cells and early‐passage rat embryonic fibroblasts

1986 • 26 citations

G Proteins, Cytoskeleton and Cancer

1998 • 18 citations

Biological effects of a murine retrovirus carrying an activated N-ras gene of human origin

1987 • 15 citations