Interferon-gamma in the first-line therapy of ovarian cancer: a randomized phase III trial

CELLULAR RESPONSES TO INTERFERON-γ

1997 • 2,885 citations

Cyclophosphamide and Cisplatin Compared with Paclitaxel and Cisplatin in Patients with Stage III and Stage IV Ovarian Cancer

1996 • 2,766 citations

Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice

1998 • 1,400 citations

Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFNγ receptors

1994 • 619 citations

Interferon-γ: Biology and Role in Pathogenesis

1996 • 433 citations

A monoclonal antibody against the c-erbB-2 protein enhances the cytotoxicity of cis-diamminedichloroplatinum against human breast and ovarian tumor cell lines.

1991 • 229 citations

Intraperitoneal recombinant alpha-interferon for "salvage" immunotherapy in stage III epithelial ovarian cancer: a Gynecologic Oncology Group Study.

1985 • 181 citations

Intraperitoneal recombinant interferon gamma in ovarian cancer patients with residual disease at second-look laparotomy.

1996 • 158 citations

The determination of an immunologically active dose of interferon-gamma in patients with melanoma.

1988 • 123 citations

Activation or suppression of the tumoricidal properties of monocytes from cancer patients following treatment with human recombinant gamma-interferon.

1986 • 86 citations

Anti‐tumor and immunomodulatory activity of intraperitoneal IFN‐γ in ovarian carcinoma patients with minimal residual tumor after chemotherapy

1992 • 79 citations

Intraperitoneal recombinant gamma-interferon in patients with recurrent ascitic ovarian carcinoma: modulation of cytotoxicity and cytokine production in tumor-associated effectors and of major histocompatibility antigen expression on tumor cells.

1990 • 73 citations

Direct and indirect effects of human recombinant gamma-interferon on tumor cells in a clonogenic assay.

1986 • 60 citations

A phase I trial of intraperitoneal recombinant gamma-interferon in advanced ovarian carcinoma.

1988 • 58 citations

Gamma-interferon reduces expression of the protooncogene c-erbB-2 in human ovarian carcinoma cells.

1990 • 56 citations

Interferon-γ is required in activation of macrophages for tumor cytotoxicity

1983 • 53 citations

Different effects of interferons, interleukin-1β and tumor necrosis factor-α in normal (OSE) and malignant human ovarian epithelial cells

1996 • 47 citations

Modulation of ovarian carcinoma tumor marker CA-125 by gamma-interferon.

1989 • 44 citations

Cyclophosphamide and Cisplatin Compared with Paclitaxel and Cisplatin in Patients with Stage III and Stage IV Ovarian Cancer

1996 • 41 citations

Antitumor activity of gamma-interferon in ascitic and solid tumor models of human ovarian cancer.

1991 • 39 citations

A Phase II Study of the Efficacy of Recombinant Interferon Gamma in Relapsing Ovarian Adenocarcinoma

1988 • 36 citations

Interferon-γ for the treatment of metastatic renal cancer: Dose-dependent stimulation and downregulation of beta2 microglobulin and neopterin responses

1987 • 34 citations

Cisplatin resistance is associated with reduced interferon-γ-sensitivity and increased HER-2 expression in cultured ovarian carcinoma cells

1997 • 30 citations

Modulation of cisplatin cytotoxicity by human recombinant interferon-γ in human ovarian cancer cell lines

1994 • 24 citations

Effect of Prior Cancer Chemotherapy on Human Tumor-Specific Cytotoxicity In Vitro in Response to Immunopotentiating Biologic Response Modifiers

1991 • 16 citations

Intraperitoneal recombinant interferongamma in ovarian cancer patients with residual disease at second look laparotomy

1995 • 11 citations

Interferon- γ for the Treatment of Metastatic Renal Cancer: Dose-Dependent Stimulation and Downregulation of Beta-2 Microglobulin and Neopterin Responses

1989 • 3 citations