Transactivation through Ets and Ap1 transcription sites determines the expression of the tumor-suppressing gene maspin.

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1991 • 2,774 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Fos and jun: The AP-1 connection

1988 • 1,597 citations

Multiple hormone interactions in the developmental biology of the mammary gland.

1980 • 866 citations

The Ets family of transcription factors

1993 • 848 citations

The c-ets proto-oncogenes encode transcription factors that cooperate with c-Fos and c-Jun for transcriptional activation

1990 • 507 citations

The collagenase gene promoter contains a TPA and oncogene-responsive unit encompassing the PEA3 and AP-1 binding sites.

1990 • 450 citations

Urokinase-plasminogen activator, a new and independent prognostic marker in breast cancer.

1990 • 294 citations

A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene.

1995 • 267 citations

Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types.

1989 • 266 citations

Down-regulation of retinoic acid receptor beta in mammary carcinoma cell lines and its up-regulation in senescing normal mammary epithelial cells.

1994 • 183 citations

Modulation of Transcription Factor Ets-1 DNA Binding: DNA-Induced Unfolding of an α Helix

1995 • 177 citations

Essential AP-1 and PEA3 binding elements in the human urokinase enhancer display cell type-specific activity.

1991 • 168 citations

Production, purification, and characterization of recombinant maspin proteins.

1994 • 163 citations

Inhibition by retinoic acid of type IV collagenolysis and invasion through reconstituted basement membrane by metastatic rat mammary adenocarcinoma cells.

1989 • 151 citations

Increase of urokinase-type plasminogen activator gene expression in human lung and breast carcinomas.

1987 • 136 citations

A regulatory element that mediates co-operation between a PEA3-AP-1 element and an AP-1 site is required for phorbol ester induction of urokinase enhancer activity in HepG2 hepatoma cells.

1992 • 126 citations

JUN cooperates with the ETS domain protein pointed to induce photoreceptor R7 fate in the Drosophila eye

1995 • 118 citations

A mammary cell-specific enhancer in mouse mammary tumor virus DNA is composed of multiple regulatory elements including binding sites for CTF/NFI and a novel transcription factor, mammary cell-activating factor.

1992 • 117 citations

A single ets-related transcription factor, E1AF, confers invasive phenotype on human cancer cells.

1996 • 117 citations

A polyomavirus enhancer A-binding protein-3 site and Ets-2 protein have a major role in the 12-O-tetradecanoylphorbol-13-acetate response of the human stromelysin gene.

1993 • 112 citations

Modulation of c-"os gene transcription by negative and positive cellular factors

1987 • 110 citations

PEA3 is overexpressed in mouse metastatic mammary adenocarcinomas.

1993 • 80 citations

Identification of human granzyme B promoter regulatory elements interacting with activated T-cell-specific proteins: implication of Ikaros and CBF binding sites in promoter activation.

1995 • 72 citations

A newly established metastatic breast tumor cell line with integrated amplified copies of ERBB2 and double minute chromosomes

1989 • 36 citations

Binding of the Ets Factor GA-Binding Protein to an Upstream Site in the Factor IX Promoter Is a Critical Event in Transactivation

1996 • 28 citations

Oncogenic conversion alters the transcriptional properties of ets.

1992 • 22 citations