Current trends in transplant immunology

J Heart Lung Transplant 2021;40(4).

2021 • 6,783 citations

CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates

1997 • 936 citations

Randomised trial of basiliximab versus placebo for control of acute cellular rejection in renal allograft recipients

1997 • 757 citations

Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes

1998 • 466 citations

EFFECTS OF EXPLOSIVE BRAIN DEATH ON CYTOKINE ACTIVATION OF PERIPHERAL ORGANS IN THE RAT1

1998 • 409 citations

A BLINDED, LONG-TERM, RANDOMIZED MULTICENTER STUDY OF MYCOPHENOLATE MOFETIL IN CADAVERIC RENAL TRANSPLANTATION

1998 • 403 citations

No evidence of pig DNA or retroviral infection in patients with short-term extracorporeal connection to pig kidneys

1998 • 291 citations

POSTTRANSPLANT THERAPY USING HIGH-DOSE HUMAN IMMUNOGLOBULIN (INTRAVENOUS GAMMAGLOBULIN) TO CONTROL ACUTE HUMORAL REJECTION IN RENAL AND CARDIAC ALLOGRAFT RECIPIENTS AND POTENTIAL MECHANISM OF ACTION1

1998 • 268 citations

LIFE-SUPPORTING PIG-TO-PRIMATE RENAL XENOTRANSPLANTATION USING GENETICALLY MODIFIED DONORS

1998 • 265 citations

Protective genes expressed in endothelial cells: a regulatory response to injury

1997 • 222 citations

REMOVAL OF ANTI-PORCINE NATURAL ANTIBODIES FROM HUMAN AND NONHUMAN PRIMATE PLASMA IN VITRO AND IN VIVO BY A Gal??1-3Gal??1-4??Glc-X IMMUNOAFFINITY COLUMN

1998 • 197 citations

CD40 signaling in vascular cells: A key role in atherosclerosis?

1998 • 189 citations

Chronic cardiac rejection in the LEW to F344 rat model. Blockade of CD28-B7 costimulation by CTLA4Ig modulates T cell and macrophage activation and attenuates arteriosclerosis.

1996 • 179 citations

Blockade of T-cell costimulation prevents development of experimental chronic renal allograft rejection.

1996 • 170 citations

HISTOLOGIC FEATURES OF CHRONIC ALLOGRAFT NEPHROPATHY REVEALED BY PROTOCOL BIOPSIES IN KIDNEY TRANSPLANT RECIPIENTS

1998 • 152 citations

MOLECULAR EXECUTORS OF CELL DEATH-DIFFERENTIAL INTRARENAL EXPRESSION OF Fas LIGAND, Fas, GRANZYME B, AND PERFORIN DURING ACUTE AND/OR CHRONIC REJECTION OF HUMAN RENAL ALLOGRAFTS1,2

1996 • 152 citations

The use of antibodies against the IL-2 receptor in transplantation

1998 • 138 citations

Hyperacute rejections of two consecutive renal allografts and early loss of the third transplant caused by non-HLA antibodies specific for endothelial cells

1997 • 134 citations

Backleak, tight junctions, and cell- cell adhesion in postischemic injury to the renal allograft.

1998 • 133 citations

Late blockade of T cell costimulation interrupts progression of experimental chronic allograft rejection.

1998 • 129 citations

Ligation of CD40 Activates Interleukin 1β-converting Enzyme (Caspase-1) Activity in Vascular Smooth Muscle and Endothelial Cells and Promotes Elaboration of Active Interleukin 1β

1997 • 123 citations

Chronic allograft nephropathy in the rat is improved by angiotensin II receptor blockade but not by calcium channel antagonism.

1998 • 120 citations

The prognostic significance of specific arterial lesions in acute renal allograft rejection.

1998 • 118 citations

DONOR ANTIGEN IS NECESSARY FOR THE PREVENTION OF CHRONIC REJECTION IN CTLA4IG-TREATED MURINE CARDIAC ALLOGRAFT RECIPIENTS1,2

1997 • 114 citations

PREVENTION OF LATE RENAL CHANGES AFTER INITIAL ISCHEMIA/REPERFUSION INJURY BY BLOCKING EARLY SELECTIN BINDING1

1997 • 110 citations

FAS LIGAND GENE TRANSFER TO RENAL ALLOGRAFTS IN RATS

1998 • 106 citations

OXIDATIVE STRESS AND LIPID ABNORMALITIES IN RENAL TRANSPLANT RECIPIENTS WITH OR WITHOUT CHRONIC REJECTION1

1998 • 105 citations

PREVENTION OF CHRONIC REJECTION IN MOUSE AORTIC ALLOGRAFTS BY COMBINED TREATMENT WITH CTLA4-Ig AND ANTI-CD40 LIGAND MONOCLONAL ANTIBODY1,2

1997 • 96 citations

HLA CLASS I AND CLASS II ANTIBODIES

1998 • 74 citations

ENZYME-LINKED IMMUNOSORBENT ASSAY SPOT DETECTION OF INTERFERON-?? AND INTERLEUKIN 5-PRODUCING CELLS AS AS PREDICTIVE MARKER FOR RENAL ALLOGRAFT FAILURE1

1998 • 69 citations

The intragraft gene activation of markers reflecting T-cell-activation and -cytotoxicity analyzed by quantitative RT-PCR in renal transplantation.

1996 • 62 citations

Tolerance induction ameliorates allograft vasculopathy in rat aortic transplants. Influence of Fas-mediated apoptosis.

1998 • 61 citations

APOPTOTIC CELL DEATH IN HUMAN CHRONIC RENAL ALLOGRAFT REJECTION

1997 • 61 citations

BASELINE GLOMERULAR SIZE AS A PREDICTOR OF FUNCTION IN HUMAN RENAL TRANSPLANTATION1

1998 • 60 citations

T-CELL COSTIMULATORY BLOCKADE IN EXPERIMENTAL CHRONIC CARDIAC ALLOGRAFT REJECTION

1997 • 59 citations

CHRONIC BLOCKADE OF CD28-B7-MEDIATED T-CELL COSTIMULATION BY CTLA4Ig REDUCES INTIMAL THICKENING IN MHC CLASS I AND II INCOMPATIBLE MOUSE HEART ALLOGRAFTS1,2

1997 • 58 citations

High rate of acute rejections in renal allograft recipients with thrombophilic risk factors.

1998 • 56 citations

Contribution of early acute rejection episodes to chronic rejection in a rat kidney retransplantation model

1998 • 49 citations

HLA ANTIBODIES PRESENT IN THE SERA OF SENSITIZED PATIENTS AWAITING RENAL TRANSPLANT ARE ALSO REACTIVE TO SWINE LEUKOCYTE ANTIGENS1,2

1998 • 48 citations

EFFICACY AND SAFETY OF LOW MOLECULAR WEIGHT HEPARIN IN RENAL TRANSPLANTATION1

1998 • 48 citations

MECHANISMS OF LYMPHOCYTE-MEDIATED CYTOTOXICITY IN ACUTE RENAL ALLOGRAFT REJECTION1

1998 • 46 citations

Cytokine analysis of human renal allograft aspiration biopsy cultures supernatants predicts acute rejection.

1998 • 44 citations

Elevated neointimal endothelin-1 in transplantation-associated arteriosclerosis of renal allograft recipients

1998 • 43 citations

ROLE OF DONOR AND RECIPIENT ANTIGEN-PRESENTING CELLS IN PRIMING AND MAINTAINING T CELLS WITH INDIRECT ALLOSPECIFICITY1

1998 • 42 citations

CHRONIC RENAL ALLOGRAFT REJECTION

1998 • 41 citations

INCREASED CD40 LIGAND GENE EXPRESSION DURING HUMAN RENAL AND MURINE ISLET ALLOGRAFT REJECTION1

1998 • 38 citations

Medial smooth muscle cell loss in arterial allografts occurs by cytolytic cell induced apoptosis1

1998 • 33 citations

ACTIVATION OF THE SERINE PROTEINASE SYSTEM IN CHRONIC KIDNEY REJECTION1

1998 • 31 citations

HUMANIZED IgG1 AND IgG4 ANTI-CD4 MONOCLONAL ANTIBODIES

1998 • 30 citations

Angiotensin-converting-enzyme insertion/deletion genotype and long-term renal allograft survival

1998 • 28 citations

The past, present, and future of renal xenotransplantation

1997 • 26 citations

Role of fine-needle aspiration in clinical management of transplant patients

1997 • 26 citations

DOES INCREASED URINARY INTERLEUKIN-1 RECEPTOR ANTAGONIST/INTERLEUKIN-1?? RATIO INDICATE GOOD PROGNOSIS IN RENAL TRANSPLANT RECIPIENTS?

1998 • 25 citations

Expression of inducible lymphocyte costimulatory molecules in human renal allograft

1998 • 25 citations

Epithelial- and endothelial-cell specificity of renal graft infiltrating T cells.

1998 • 24 citations

IN VIVO CLASS II TRANSACTIVATOR EXPRESSION IN MICE IS INDUCED BY A NON-INTERFERON-?? MECHANISM IN RESPONSE TO LOCAL INJURY1,2

1997 • 22 citations

Myocardial apoptosis in a heterotopic murine heart transplantation model of chronic rejection and graft vasculopathy.

1997 • 22 citations

Expression of Fas and Fas Ligand in Renal Grafts with Acute and Chronic Rejection in the Rat Model

1997 • 20 citations

TGF-β in Renal Allograft Rejection

1998 • 18 citations

SULFATION-DEPENDENT DOWN-REGULATION OF INTERFERON-??-INDUCED MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I AND II AND INTERCELLULAR ADHESION MOLECULE-1 EXPRESSION ON TUBULAR AND ENDOTHELIAL CELLS BY GLYCOSAMINOGLYCANS1

1998 • 17 citations

Cytokine analysis of human renal allograft aspiration biopsy cultures supernatants predicts acute rejection

1998 • 15 citations

IMMUNOBIOLOGY OF RENAL TRANSPLANTATION

1998 • 14 citations

PROLONGATION OF SURVIVAL OF PRIMARY RENAL ALLOGRAFTS BY FEEDING OF DONOR SPLEEN CELLS1

1998 • 13 citations

Role of genetic variants of the renin-angiotensin system in chronic renal allograft injury

1998 • 10 citations

TOLERANCE INDUCTION BY INTRATHYMIC INOCULATION PREVENTS CHRONIC RENAL ALLOGRAFT REJECTION1,2

1998 • 10 citations

TUBULAR ANTITHROMBIN AT TRANSPLANTATION DETERMINES SUBSEQUENT RENAL ALLOGRAFT FUNCTION1,2

1998 • 8 citations

Can a diagnosis of renal allograft rejection be based on histology alone?

1998 • 7 citations

Renal transplant biopsy: what does it tell?

1997 • 1 citations