ROLE OF DONOR AND RECIPIENT ANTIGEN-PRESENTING CELLS IN PRIMING AND MAINTAINING T CELLS WITH INDIRECT ALLOSPECIFICITY1

Statistical Method in Biological Assay.

1979 • 3,679 citations

Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles.

1993 • 900 citations

Restoration of immunogenicity to passenger cell-depleted kidney allografts by the addition of donor strain dendritic cells.

1982 • 807 citations

A routine method for the establishment of permanent growing lymphoblastoid cell lines

1986 • 628 citations

Why do so many lymphocytes respond to major histocompatibility antigens?

1977 • 462 citations

The role of "indirect" recognition in initiating rejection of skin grafts from major histocompatibility complex class II-deficient mice.

1993 • 325 citations

INDIRECT ALLORECOGNITION OF MAJOR HISTOCOMPATIBILITY COMPLEX ALLOPEPTIDES IN HUMAN RENAL TRANSPLANT RECIPIENTS WITH CHRONIC GRAFT DYSFUNCTION1

1997 • 290 citations

The molecular basis of alloreactivity

1990 • 278 citations

Donor major histocompatibility complex (MHC) peptides are presented by recipient MHC molecules during graft rejection.

1992 • 266 citations

Indirect recognition of donor HLA-DR peptides in organ allograft rejection.

1996 • 244 citations

Contribution of direct and indirect recognition pathways to T cell alloreactivity.

1993 • 242 citations

Rejection of skin allografts by indirect allorecognition of donor class I major histocompatibility complex peptides.

1992 • 218 citations

High determinant density may explain the phenomenon of alloreactivity

1984 • 194 citations

Antigen presentation by keratinocytes induces tolerance in human T cells

1990 • 176 citations

In vitro peptide binding to soluble empty class I major histocompatibility complex molecules isolated from transfected Drosophila melanogaster cells.

1992 • 134 citations

Major histocompatibility complex class II-expressing endothelial cells induce allospecific nonresponsiveness in naive T cells.

1996 • 127 citations

T cells sensitized to synthetic HLA-DR3 peptide give evidence of continuous presentation of denatured HLA-DR3 molecules by HLA-DP.

1989 • 117 citations

Cytotoxic T cell recognition of an endogenous class I HLA peptide presented by a class II HLA molecule.

1990 • 109 citations

Presentation of alloantigens by host cells

1986 • 100 citations

MECHANISMS OF ALLO-RECOGNITION

1994 • 94 citations

Antigen presentation by epithelial cells induces anergic immunoregulatory CD45RO+ T cells and deletion of CD45RA+ T cells.

1997 • 87 citations

MECHANISMS OF ALLO-RECOGNITION

1994 • 85 citations

INDIRECT T CELL ALLORECOGNITION OF DONOR ANTIGENS CONTRIBUTES TO THE REJECTION OF VASCULARIZED KIDNEY ALLOGRAFTS

1995 • 74 citations

THE INDIRECT PATHWAY OF ALLORECOGNITION

1995 • 74 citations

T cell recognition of donor major histocompatibility complex class Ipeptides during allograft rejection

1992 • 73 citations

Antigen presentation by interferon‐γ‐treated thyroid follicular cells inhibits interleukin‐2 (IL‐2) and supports IL‐4 production by B7‐dependent human T cells

1997 • 70 citations

Allorecognition of isolated, denatured chains of class I and class II major histocompatibility complex molecules. Evidence for an important role for indirect allorecognition in transplantation

1992 • 66 citations

Interferon-γ-treated renal tubular epithelial cells induce allospecific tolerance

1998 • 64 citations

ANALYSIS OF THE ALLOREACTIVE T CELL REPERTOIRE IN MAN

1987 • 61 citations

RENAL ALLOGRAFT REJECTION

1968 • 52 citations

Corecognition of HLA-A1 and HLA-DPw3 by a human CD4+ alloreactive T lymphocyte clone.

1990 • 52 citations

Stimulated renal tubular epithelial cells induce anergy in CD4+ T cells

1993 • 46 citations

OPTIMIZING A LIMITING DILUTION CULTURE SYSTEM FOR QUANTIFYING THE FREQUENCY OF INTERLEUKIN-2-PRODUCING ALLOREACTIVE T HELPER LYMPHOCYTES1

1997 • 34 citations

RENAL ALLOGRAFT REJECTION

1995 • 32 citations

PERIPHERAL MONITORING OF DIRECT AND INDIRECT ALLOANTIGEN PRESENTATION PATHWAYS IN CLINICAL HEART TRANSPLANT RECIPIENTS1

1996 • 14 citations