Blockade of T-cell costimulation prevents development of experimental chronic renal allograft rejection.

The Role of the CD28 Receptor During T Cell Responses to Antigen

1993 • 1,320 citations

CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2.

1995 • 532 citations

New perspectives of C1328-137-mediated T cell costimulation

1995 • 526 citations

Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion.

1993 • 502 citations

Renal Transplantation

1994 • 428 citations

BOTH ALLOANTIGEN-DEPENDENT AND -INDEPENDENT FACTORS INFLUENCE CHRONIC ALLOGRAFT REJECTION

1995 • 378 citations

Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation?

1995 • 347 citations

TRANSPLANTATION TOLERANCE INDUCED BY CTLA4-Ig1

1994 • 303 citations

ISCHEMIC ACUTE TUBULAR NECROSIS INDUCES AN EXTENSIVE LOCAL CYTOKINE RESPONSE

1995 • 271 citations

Chronic renal transplant loss

1995 • 254 citations

Sequential cytokine dynamics in chronic rejection of rat renal allografts: roles for cytokines RANTES and MCP-1.

1995 • 222 citations

CYTOKINES, ADHESION MOLECULES, AND THE PATHOGENESIS OF CHRONIC REJECTION OF RAT RENAL ALLOGRAFTS

1993 • 218 citations

MECHANISMS OF T CELL RECOGNITION OF ALLOANTIGEN

1994 • 205 citations

Intragraft TGF-β1 mRNA: A correlate of interstitial fibrosis and chronic allograft nephropathy

1996 • 193 citations

Chronic cardiac rejection in the LEW to F344 rat model. Blockade of CD28-B7 costimulation by CTLA4Ig modulates T cell and macrophage activation and attenuates arteriosclerosis.

1996 • 179 citations

Transforming growth factor-beta and matrix protein expression in acute and chronic rejection of human renal allografts.

1995 • 148 citations

UPREGULATION OF CYTOKINES ASSOCIATED WITH MACROPHAGE ACTIVATION IN THE LEWIS-TO-F344 RAT TRANSPLANTATION MODEL OF CHRONIC CARDIAC REJECTION1,2

1995 • 141 citations

Chronic transplant rejection

1994 • 135 citations

Early and persistent induction of monocyte chemoattractant protein 1 in rat cardiac allografts.

1993 • 128 citations

PROGRESSIVE ALBUMINURIA AND GLOMERULOSCLEROSIS IN A RAT MODEL OF CHRONIC RENAL ALLOGRAFT REJECTION

1992 • 109 citations

PREVENTION OF FUNCTIONAL, STRUCTURAL, AND MOLECULAR CHANGES OF CHRONIC REJECTION OF RAT RENAL ALLOGRAFTS BY A SPECIFIC MACROPHAGE INHIBITOR1,2

1995 • 78 citations

T cell costimulatory pathways

1995 • 73 citations

Long-term failure of renal transplants: adding insult to injury.

1995 • 65 citations

EVIDENCE THAT RECIPIENT CD8+ T CELL DEPLETION DOES NOT ALTER DEVELOPMENT OF CHRONIC VASCULAR REJECTION IN A RAT HEART ALLOGRAFT MODEL

1994 • 38 citations