Deletion analysis of the internal signal-anchor domain of the human asialoglycoprotein receptor H1.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Carbohydrate-Specific Receptors of the Liver

1982 • 1,895 citations

Isolation of intracellular membranes by means of sodium carbonate treatment: application to endoplasmic reticulum.

1982 • 1,765 citations

Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

1984 • 1,533 citations

Protein translocation across the endoplasmic reticulum

1984 • 825 citations

Translocation of proteins across the endoplasmic reticulum III. Signal recognition protein (SRP) causes signal sequence-dependent and site-specific arrest of chain elongation that is released by microsomal membranes.

1981 • 807 citations

Compilation of published signal sequences

1984 • 784 citations

Multiple Mechanisms of Protein Insertion into and Across Membranes

1985 • 720 citations

[6] Preparation of microsomal membranes for cotranslational protein translocation

1983 • 679 citations

Many Random Sequences Functionally Replace the Secretion Signal Sequence of Yeast Invertase

1987 • 375 citations

Translocation of secretory proteins across the microsomal membrane occurs through an environment accessible to aqueous perturbants

1985 • 277 citations

An internal signal sequence: The asialoglycoprotein receptor membrane anchor

1986 • 209 citations

An artificial anchor domain: hydrophobicity suffices to stop transfer

1985 • 206 citations

The Hepatic Asialoglycoprotein Recepto

1984 • 185 citations

Sequence of a second human asialoglycoprotein receptor: conservation of two receptor genes during evolution.

1985 • 182 citations

Sequence of human asialoglycoprotein receptor cDNA. An internal signal sequence for membrane insertion.

1985 • 182 citations

Structural requirements of a membrane-spanning domain for protein anchoring and cell surface transport

1985 • 173 citations

[41] Preparation of a cell-free protein-synthesizing system from wheat germ

1983 • 169 citations

Using Recombinant DNA Techniques to Study Protein Targeting in the Eucaryotic Cell

1985 • 158 citations

NH2-terminal hydrophobic region of influenza virus neuraminidase provides the signal function in translocation.

1984 • 156 citations

[53] Signal recognition particle: A ribonucleoprotein required for cotranslational translocation of proteins, isolation and properties

1983 • 155 citations

Mechanisms of integration of de novo-synthesized polypeptides into membranes: signal-recognition particle is required for integration into microsomal membranes of calcium ATPase and of lens MP26 but not of cytochrome b5.

1983 • 155 citations

Fine structure of a membrane anchor domain

1985 • 151 citations

The transmembrane segment of the human transferrin receptor functions as a signal peptide.

1986 • 151 citations

The membrane-spanning segment of invariant chain (Iγ) contains a potentially cleavable signal sequence

1986 • 142 citations

Incorporation of a charged amino acid into the membrane-spanning domain blocks cell surface transport but not membrane anchoring of a viral glycoprotein.

1985 • 93 citations

Foreign transmembrane peptides replacing the internal signal sequence of transferrin receptor allow its translocation and membrane binding

1987 • 75 citations

Signal recognition particle-dependent membrane insertion of mouse invariant chain: a membrane-spanning protein with a cytoplasmically exposed amino terminus.

1986 • 69 citations

Mutational analysis of the signal-anchor domain of influenza virus neuraminidase.

1987 • 57 citations

Mutants of the membrane-binding region of Semliki Forest virus E2 protein. I. Cell surface transport and fusogenic activity.

1986 • 54 citations

A stop transfer sequence recognizes receptors for nascent chain translocation across the endoplasmic reticulum membrane

1986 • 54 citations

Mutants of the membrane-binding region of Semliki Forest virus E2 protein. II. Topology and membrane binding.

1986 • 44 citations

Incorporation of a Charged Amino Acid into the Membrane-Spanning Domain Blocks Cell Surface Transport But Not Membrane Anchoring of a Viral Glycoprotein

1985 • 41 citations