Foreign transmembrane peptides replacing the internal signal sequence of transferrin receptor allow its translocation and membrane binding

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

Quantitative Film Detection of 3H and 14C in Polyacrylamide Gels by Fluorography

1975 • 4,693 citations

Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNA

1985 • 2,505 citations

Translocation of proteins across the endoplasmic reticulum III. Signal recognition protein (SRP) causes signal sequence-dependent and site-specific arrest of chain elongation that is released by microsomal membranes.

1981 • 807 citations

Compilation of published signal sequences

1984 • 784 citations

Multiple Mechanisms of Protein Insertion into and Across Membranes

1985 • 720 citations

Primary structure and transmembrane orientation of the murine anion exchange protein

1985 • 552 citations

Purification of a membrane-associated protein complex required for protein translocation across the endoplasmic reticulum.

1980 • 502 citations

Nucleotide sequence of cDNA coding for Semliki Forest virus membrane glycoproteins

1980 • 428 citations

Primary structure of human transferrin receptor deduced from the mRNA sequence

1984 • 351 citations

Structural features of the cell surface receptor for transferrin that is recognized by the monoclonal antibody OKT9.

1982 • 275 citations

Antigenic drift between the haemagglutinin of the Hong Kong influenza strains A/Aichi/2/68 and A/Victoria/3/75

1980 • 243 citations

Complete structure of the hemagglutinin gene from the human influenza A/Victoria/3/75 (H3N2) strain as determined from cloned DNA

1980 • 225 citations

An internal signal sequence: The asialoglycoprotein receptor membrane anchor

1986 • 209 citations

An artificial anchor domain: hydrophobicity suffices to stop transfer

1985 • 206 citations

A 70-kd protein of the yeast mitochondrial outer membrane is targeted and anchored via its extreme amino terminus.

1984 • 198 citations

The presequences of two imported mitochondrial proteins contain information for intracellular and intramitochondrial sorting

1986 • 194 citations

Bovine opsin has more than one signal sequence

1985 • 186 citations

Structural requirements of a membrane-spanning domain for protein anchoring and cell surface transport

1985 • 173 citations

Using Recombinant DNA Techniques to Study Protein Targeting in the Eucaryotic Cell

1985 • 158 citations

Sequencing of the nuclear gene for the yeast cytochrome c1 precursor reveals an unusually complex amino-terminal presequence.

1984 • 157 citations

NH2-terminal hydrophobic region of influenza virus neuraminidase provides the signal function in translocation.

1984 • 156 citations

Fine structure of a membrane anchor domain

1985 • 151 citations

The transmembrane segment of the human transferrin receptor functions as a signal peptide.

1986 • 151 citations

A stop transfer sequence confers predictable transmembrane orientation to a previously secreted protein in cell-free systems

1983 • 142 citations

Towards a comparative anatomy of N-terminal topogenic protein sequences

1986 • 140 citations

The first twelve amino acids of a yeast mitochondrial outer membrane protein can direct a nuclear-coded cytochrome oxidase subunit to the mitochondrial inner membrane.

1985 • 140 citations

Structure and Assembly of Alphaviruses

1982 • 134 citations

Transmembrane movement of oligosaccharide-lipids during glycoprotein synthesis

1984 • 121 citations

Import of proteins into mitochondria: nucleotide sequence of the gene for a 70-kd protein of the yeast mitochondrial outer membrane.

1983 • 110 citations

Chapter 4 Structural and Thermodynamic Aspects of the Transfer of Proteins into and across Membranes

1985 • 96 citations

Incorporation of a charged amino acid into the membrane-spanning domain blocks cell surface transport but not membrane anchoring of a viral glycoprotein.

1985 • 93 citations

Expression of Semliki Forest virus proteins from cloned complementary DNA. I. The fusion activity of the spike glycoprotein.

1983 • 91 citations

Signal recognition particle (SRP) does not mediate a translational arrest of nascent secretory proteins in mammalian cell-free systems.

1985 • 73 citations

Signal recognition particle-dependent membrane insertion of mouse invariant chain: a membrane-spanning protein with a cytoplasmically exposed amino terminus.

1986 • 69 citations

Reinitiation of translocation in the Semliki Forest virus structural polyprotein: identification of the signal for the E1 glycoprotein.

1986 • 59 citations

Mutants of the membrane-binding region of Semliki Forest virus E2 protein. I. Cell surface transport and fusogenic activity.

1986 • 54 citations

Mutants of the membrane-binding region of Semliki Forest virus E2 protein. II. Topology and membrane binding.

1986 • 44 citations

Glycosylation and surface expression of the influenza virus neuraminidase requires the N-terminal hydrophobic region.

1984 • 40 citations

POST‐TRANSLATIONAL UPTAKE OF CYTOPLASMICALLY SYNTHESIZED PROTEINS BY INTACT CHLOROPLASTS IN VITRO*

1980 • 39 citations

In vitro biosynthesis of the human cell surface receptor for transferrin

1983 • 21 citations

Deleted Work

1955 • 0 citations