The transmembrane segment of the human transferrin receptor functions as a signal peptide.

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

1984 • 1,533 citations

Intracellular protein topogenesis

1980 • 1,378 citations

Transfer of proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components.

1975 • 1,175 citations

Mechanisms for the incorporation of proteins in membranes and organelles.

1982 • 875 citations

Protein translocation across the endoplasmic reticulum

1984 • 825 citations

Compilation of published signal sequences

1984 • 784 citations

Multiple Mechanisms of Protein Insertion into and Across Membranes

1985 • 720 citations

Recognition of cap structure in splicing in vitro of mRNA precursors

1984 • 575 citations

The structure of bovine rhodopsin

1983 • 513 citations

Primary structure of human transferrin receptor deduced from the mRNA sequence

1984 • 351 citations

A novel in vitro transcription-translation system: accurate and efficient synthesis of single proteins from cloned DNA sequences.

1984 • 251 citations

An internal signal sequence: The asialoglycoprotein receptor membrane anchor

1986 • 209 citations

An artificial anchor domain: hydrophobicity suffices to stop transfer

1985 • 206 citations

Bovine opsin has more than one signal sequence

1985 • 186 citations

Structural requirements of a membrane-spanning domain for protein anchoring and cell surface transport

1985 • 173 citations

Using Recombinant DNA Techniques to Study Protein Targeting in the Eucaryotic Cell

1985 • 158 citations

NH2-terminal hydrophobic region of influenza virus neuraminidase provides the signal function in translocation.

1984 • 156 citations

Fine structure of a membrane anchor domain

1985 • 151 citations

Incorporation of a charged amino acid into the membrane-spanning domain blocks cell surface transport but not membrane anchoring of a viral glycoprotein.

1985 • 93 citations

Reinitiation of translocation in the Semliki Forest virus structural polyprotein: identification of the signal for the E1 glycoprotein.

1986 • 59 citations

Isolation of cDNA clones for the human transferrin receptor.

1983 • 46 citations

Mutants of the membrane-binding region of Semliki Forest virus E2 protein. II. Topology and membrane binding.

1986 • 44 citations

Incorporation of a Charged Amino Acid into the Membrane-Spanning Domain Blocks Cell Surface Transport But Not Membrane Anchoring of a Viral Glycoprotein

1985 • 41 citations

Structural and evolutionary analysis of the two chimpanzee α-globin mRNAs

1983 • 41 citations

Glycosylation and surface expression of the influenza virus neuraminidase requires the N-terminal hydrophobic region.

1984 • 40 citations

POST‐TRANSLATIONAL UPTAKE OF CYTOPLASMICALLY SYNTHESIZED PROTEINS BY INTACT CHLOROPLASTS IN VITRO*

1980 • 39 citations

Pushing the signal hypothesis: what are the limits?

1985 • 37 citations

In vitro biosynthesis of the human cell surface receptor for transferrin

1983 • 21 citations

Glycosylation and Surface Expression of the Influenza Virus Neuraminidase Requires the N-Terminal Hydrophobic Region

1984 • 17 citations