Progesterone Regulates Granulosa Cell Viability Through a Protein Kinase G-Dependent Mechanism That May Involve 14-3-3σ1

Quantitative profiling of differentiation-induced microsomal proteins using isotope-coded affinity tags and mass spectrometry

2001 • 891 citations

Ovarian Follicle Atresia: A Hormonally Controlled Apoptotic Process*

1994 • 728 citations

14-3-3-affinity purification of over 200 human phosphoproteins reveals new links to regulation of cellular metabolism, proliferation and trafficking

2004 • 453 citations

Distinct and specific functions of cGMP-dependent protein kinases

1997 • 394 citations

Global quantitative phosphoprotein analysis using Multiplexed Proteomics technology

2003 • 385 citations

Prolongation of ovarian lifespan into advanced chronological age by Bax-deficiency

1999 • 368 citations

Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction

1997 • 354 citations

Hormonal regulation of apoptosis in early antral follicles: follicle-stimulating hormone as a major survival factor.

1996 • 339 citations

14-3-3 Proteins Mediate an Essential Anti-apoptotic Signal

2001 • 305 citations

Stoichiometric and reversible phosphorylation of a 46-kDa protein in human platelets in response to cGMP- and cAMP-elevating vasodilators.

1990 • 270 citations

Bad -deficient mice develop diffuse large B cell lymphoma

2003 • 268 citations

Analysis of Steady-state Protein Phosphorylation in Mitochondria Using a Novel Fluorescent Phosphosensor Dye

2003 • 232 citations

Nitric Oxide Protects PC12 Cells from Serum Deprivation-Induced Apoptosis by cGMP-Dependent Inhibition of Caspase Signaling

1999 • 225 citations

Involvement of Cyclic GMP and Protein Kinase G in the Regulation of Apoptosis and Survival in Neural Cells

2002 • 177 citations

The Dimeric Versus Monomeric Status of 14-3-3ζ Is Controlled by Phosphorylation of Ser58 at the Dimer Interface

2003 • 174 citations

Specificity of 14-3-3 isoform dimer interactions and phosphorylation

2002 • 168 citations

Preantral Ovarian Follicles in Serum-Free Culture: Suppression of Apoptosis after Activation of the Cyclic Guanosine 3′,5′-Monophosphate Pathway and Stimulation of Growth and Differentiation by Follicle-Stimulating Hormone*

1997 • 158 citations

Nitric oxide prevents 6‐hydroxydopamine‐induced apoptosis in PC12 cells through cGMP‐dependent PI3 kinase/Akt activation

2003 • 156 citations

The G2/M Regulator 14-3-3ς Prevents Apoptosis through Sequestration of Bax

2001 • 154 citations

Highly specific, membrane-permeant peptide blockers of cGMP-dependent protein kinase Iα inhibit NO-induced cerebral dilation

2000 • 151 citations

cAMP-Mediated Signals as Determinants for Apoptosis in Primary Granulosa Cells

1995 • 145 citations

Cyclic GMP mediates apoptosis induced by sulindac derivatives via activation of c-Jun NH2-terminal kinase 1.

2000 • 137 citations

Control of Differentiation, Transformation, and Apoptosis in Granulosa Cells by Oncogenes, Oncoviruses, and Tumor Suppressor Genes*

1997 • 134 citations

A Novel Sphingosine-dependent Protein Kinase (SDK1) Specifically Phosphorylates Certain Isoforms of 14-3-3 Protein

1998 • 130 citations

Detection of cGMP dependent protein kinase isozymes by specific antibodies

1992 • 127 citations

Significance of 14-3-3 Self-Dimerization for Phosphorylation-dependent Target Binding

2003 • 114 citations

Survival-promoting functions of 14-3-3 proteins

2002 • 109 citations

Functional Conservation of 14-3-3 Isoforms in Inhibiting Bad-Induced Apoptosis

2001 • 106 citations

Programmed Cell Death in the Ovary: Insights and Future Prospects Using Genetic Technologies

2001 • 103 citations

Basic Fibroblast Growth Factor Inhibits Apoptosis of Spontaneously Immortalized Granulosa Cells by Regulating Intracellular Free Calcium Levels through a Protein Kinase Cδ-Dependent Pathway**This work was supported by NIH Grant HD-33467.

2000 • 85 citations

The 14-3-3 proteins: gene, gene expression, and function.

2003 • 85 citations

Cyclic GMP-dependent Protein Kinase Regulates the Expression of Thioredoxin and Thioredoxin Peroxidase-1 during Hormesis in Response to Oxidative Stress-induced Apoptosis

2003 • 82 citations

Alternative pathways of ovarian apoptosis: death for life

2003 • 81 citations

Progesterone Mediates its Anti-Mitogenic and Anti-Apoptotic Actions in Rat Granulosa Cells Through a Progesterone-Binding Protein With Gamma Aminobutyric AcidA Receptor-Like Features1

1998 • 81 citations

Estrogens Enhance the Adenosine 3′,5′-Monophosphate- Mediated Induction of Follicle-Stimulating Hormone and Luteinizing Hormone Receptors in Rat Granulosa Cells

1984 • 70 citations

cGMP-dependent Protein Kinase Iβ Physically and Functionally Interacts with the Transcriptional Regulator TFII-I

2002 • 64 citations

Basic Fibroblast Growth Factor Maintains Calcium Homeostasis and Granulosa Cell Viability by Stimulating Calcium Efflux via a PKCδ-Dependent Pathway

2001 • 64 citations

Apoptosis of Granulosa Cells: A Review on the Role of MAPK‐signalling modules

2003 • 61 citations

Membrane-Initiated Events Account for Progesterone's Ability to Regulate Intracellular Free Calcium Levels and Inhibit Rat Granulosa Cell Mitosis1

2002 • 58 citations

Roles of cyclic GMP in modulating ovarian functions

2003 • 54 citations

Apoptosis of ovarian granulosa cells: Correlation with the reduced activity of ERK-signaling module

1999 • 53 citations

Functional Analysis of Type 1α cGMP-dependent Protein Kinase Using Green Fluorescent Fusion Proteins

2001 • 52 citations

Expression and Function of a Proapoptotic Bcl-2 Family Member Bcl-XL/Bcl-2-Associated Death Promoter (BAD) in Rat Ovary*

1997 • 51 citations

Synergism between Calcium and Cyclic GMP in Cyclic AMP Response Element-Dependent Transcriptional Regulation Requires Cooperation between CREB and C/EBP-β

2003 • 51 citations

Site of Action of Androgens on Follicle-Stimulating Hormone-Induced Aromatase Activity in Cultured Rat Granulosa Cells*

1984 • 49 citations

Ibudilast attenuates astrocyte apoptosis via cyclic GMP signalling pathway in an in vitro reperfusion model

2001 • 46 citations

Progesterone as a regulator of granulosa cell viability

2003 • 45 citations

Phosphorylation of NF‐κB proteins by cyclic GMP‐dependent kinase

2003 • 44 citations

Intracellular mechanisms of ovarian cell apoptosis

1998 • 26 citations

Expression Pattern and Role of a 60-Kilodalton Progesterone Binding Protein in Regulating Granulosa Cell Apoptosis: Involvement of the Mitogen-Activated Protein Kinase Cascade1

2003 • 24 citations

Proliferative and steroidogenic capabilities of rat granulosa cells of different sizes

1995 • 22 citations

Effects of Protein Kinase CK2, Extracellular Signal-regulated Kinase 2, and Protein Phosphatase 2A on a Phosphatidic Acid-preferring Phospholipase A1

2001 • 22 citations

Effect of cGMP analogues and protein kinase G blocker on secretory activity, apoptosis and the cAMP/protein kinase A system in porcine ovarian granulosa cells in vitro

2000 • 22 citations

A cGMP-Dependent Protein Kinase Assay for High Throughput Screening Based on Time-Resolved Fluorescence Resonance Energy Transfer

2001 • 21 citations

The ability of steroid hormones to control cAMP and cGMP production by human granulosa cells in culture

1995 • 19 citations

Effect of four cGMP analogues with different mechanisms of action on hormone release by porcine ovarian granulosa cells in vitro

2000 • 17 citations