The 14-3-3 proteins: gene, gene expression, and function.

Serine Phosphorylation of Death Agonist BAD in Response to Survival Factor Results in Binding to 14-3-3 Not BCL-XL

1996 • 2,627 citations

Signaling Through Scaffold, Anchoring, and Adaptor Proteins

1997 • 2,268 citations

The Structural Basis for 14-3-3:Phosphopeptide Binding Specificity

1997 • 1,592 citations

14-3-3 Proteins: Structure, Function, and Regulation

2000 • 1,552 citations

Interaction of 14-3-3 with Signaling Proteins Is Mediated by the Recognition of Phosphoserine

1996 • 1,371 citations

Is a p53-Regulated Inhibitor of G2/M Progression

1997 • 1,238 citations

14-3-3σ is required to prevent mitotic catastrophe after DNA damage

1999 • 895 citations

14-3-3 Proteins and Survival Kinases Cooperate to Inactivate BAD by BH3 Domain Phosphorylation

2000 • 634 citations

Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein

1999 • 580 citations

Crystal structure of the zeta isoform of the 14-3-3 protein

1995 • 516 citations

Structural Analysis of 14-3-3 Phosphopeptide Complexes Identifies a Dual Role for the Nuclear Export Signal of 14-3-3 in Ligand Binding

1999 • 500 citations

14-3-3 Proteins: Active Cofactors in Cellular Regulation by Serine/Threonine Phosphorylation

2002 • 496 citations

Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways

1995 • 473 citations

High frequency of hypermethylation at the 14-3-3 σ locus leads to gene silencing in breast cancer

2000 • 442 citations

14-3-3 proteins: regulation of subcellular localization by molecular interference

2000 • 410 citations

14-3-3 and its possible role in co-ordinating multiple signalling pathways

1996 • 367 citations

Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins

1999 • 351 citations

Molecular cloning of cDNA coding for brain-specific 14-3-3 protein, a protein kinase-dependent activator of tyrosine and tryptophan hydroxylases.

1988 • 332 citations

Involvement of 14-3-3 proteins in nuclear localization of telomerase

2000 • 320 citations

Association of the Cyclin-dependent Kinases and 14-3-3 Sigma Negatively Regulates Cell Cycle Progression

2000 • 305 citations

Binding of 14-3-3 proteins and nuclear export control the intracellular localization of the mitotic inducer Cdc25

1999 • 304 citations

14-3-3 proteins; bringing new definitions to scaffolding

2001 • 298 citations

Cytoplasmic Localization of Human cdc25C during Interphase Requires an Intact 14-3-3 Binding Site

1999 • 276 citations

14-3-3 Proteins Are Required for Maintenance of Raf-1 Phosphorylation and Kinase Activity

1998 • 219 citations

Phosphatidylinositol 3-Kinase Signaling Inhibits DAF-16 DNA Binding and Function via 14-3-3-dependent and 14-3-3-independent Pathways

2001 • 217 citations

14-3-3 Is Not Essential for Raf-1 Function: Identification of Raf-1 Proteins That Are Biologically Activated in a 14-3-3- and Ras-Independent Manner

1995 • 217 citations

14-3-3 proteins associate with phosphorylated simple epithelial keratins during cell cycle progression and act as a solubility cofactor.

1996 • 209 citations

14-3-3: Modulators of Signaling Proteins?

1994 • 206 citations

Inactivation of the 14-3-3 sigma gene is associated with 5' CpG island hypermethylation in human cancers.

2000 • 202 citations

Reversal of Raf-1 Activation by Purified and Membrane-Associated Protein Phosphatases

1995 • 202 citations

Bcr and Raf form a complex in vivo via 14-3-3 proteins.

1995 • 201 citations

Evolution of the 14-3-3 Protein Family: Does the Large Number of Isoforms in Multicellular Organisms Reflect Functional Specificity?

2000 • 201 citations

14-3-3s regulate global cleavage of their diverse binding partners in sugar-starved Arabidopsis cells

2000 • 194 citations

Human 14‐3‐3 Protein: Radioimmunoassay, Tissue Distribution, and Cerebrospinal Fluid Levels in Patients with Neurological Disorders

1982 • 188 citations

14-3-3 Proteins Associate with A20 in an Isoform-specific Manner and Function Both as Chaperone and Adapter Molecules

1996 • 181 citations

Interference of BAD (Bcl-xL/Bcl-2-Associated Death Promoter)-Induced Apoptosis in Mammalian Cells by 14–3-3 Isoforms and P11

1997 • 176 citations

Specificity of 14-3-3 isoform dimer interactions and phosphorylation

2002 • 168 citations

Subcellular Localisation of 14‐3‐3 Isoforms in Rat Brain Using Specific Antibodies

1994 • 166 citations

14-3-3 PROTEINS AND SIGNAL TRANSDUCTION

1996 • 164 citations

14-3-3 Is Phosphorylated by Casein Kinase I on Residue 233

1997 • 146 citations

14-3-3 proteins in neuronal development and function

1998 • 145 citations

14-3-3 proteins: eukaryotic regulatory proteins with many functions.

1999 • 137 citations

A Novel Sphingosine-dependent Protein Kinase (SDK1) Specifically Phosphorylates Certain Isoforms of 14-3-3 Protein

1998 • 130 citations

14-3-3 Isotypes facilitate coupling of protein kinase C-ζ to Raf-1: negative regulation by 14-3-3 phosphorylation

2000 • 129 citations

Laminar flow inhibits TNF-induced ASK1 activation by preventing dissociation of ASK1 from its inhibitor 14-3-3

2001 • 109 citations

Distinct forms of the protein kinase-dependent activator of tyrosine and tryptophan hydroxylases

1991 • 108 citations

Demonstration of the Phosphorylation-Dependent Interaction of Tryptophan Hydroxylase with the 14-3-3 Protein

1993 • 103 citations

Purification, Properties, and Immunohistochemical Localisation of Human Brain 14‐3‐3 Protein

1982 • 98 citations

Stimulus-Coupled Interaction of Tyrosine Hydroxylase with 14-3-3 Proteins

1999 • 96 citations

14‐3‐3 proteins control proteolysis of nitrate reductase in spinach leaves

1999 • 96 citations

Identification of the Site of Interaction of the 14-3-3 Protein with Phosphorylated Tryptophan Hydroxylase

1995 • 93 citations

Immunolocalisation of 14-3-3 isoforms in normal and scrapie-infected murine brain

2002 • 83 citations

Molecular cloning of rat cDNAs for β and γ subtypes of 14-3-3 protein and developmental changes in expression of their mRNAs in the nervous system

1993 • 81 citations

Molecular cloning of rat cDNAs for the ζ and θ subtypes of 14-3-3 protein and differential distributions of their mRNAs in the brain

1994 • 74 citations

14-3-3 protein ? chain gene (YWHAH) polymorphism and its genetic association with schizophrenia

1999 • 70 citations

Regulatory 14-3-3 protein–protein interactions in plant cells

2000 • 69 citations

Molecular cloning of cDNA to rat 14-3-3 η chain polypeptide and the neuronal expression of the mRNA in the central nervous system

1991 • 66 citations

The Signal Modulator Protein-14-3-3 Ts a Target of Sphingosine-Dependent or N,N-Dimethylsphingosine-Dependent Kinase in 3T3(A31) Cells

1995 • 65 citations

Phosphorylation-Dependent Interaction of Kinesin Light Chain 2 and the 14-3-3 Protein

2002 • 64 citations

Structure and Sites of Phosphorylation of 14-3-3 Protein: Role in Coordinating Signal Transduction Pathways

1997 • 51 citations

Preliminary analysis of the mouse cerebellum proteome

2002 • 49 citations

Effect of multiple phosphorylation events on the transcription factors FKHR, FKHRLI and AFX

2002 • 48 citations

Association of the TLX-2 Homeodomain and 14-3-3η Signaling Proteins

1998 • 42 citations

Molecular cloning and tissue-specific expression of the mouse homologue of the rat brain 14-3-3 θ protein: Characterization of its cellular and developmental pattern of expression in the male germ line

1997 • 42 citations

Structural Organization and Chromosomal Assignment of the Human 14-3-3 η Chain Gene (YWHAH)

1996 • 41 citations

14‐3‐3 proteins bind to histone and affect both histone phosphorylation and dephosphorylation

1994 • 37 citations

Developmental regulation of neuronal expression for the η subtype of the 14-3-3 protein, a putative regulatory protein for protein kinase C

1993 • 36 citations

Gene expression in cells of the central nervous system

1992 • 33 citations

cDNA cloning and chromosome assignment of the gene for human brain 14–3–3 protein η chain

1992 • 29 citations

Exoenzyme S binds its cofactor 14-3-3 through a non-phosphorylated motif

2002 • 27 citations

Subcellular differences in post‐translational modification of barley 14‐3‐3 proteins

2000 • 21 citations

Isolation and structure of the mouse 14-3-3 η chain gene and the distribution of 14-3-3 η mRNA in the mouse brain

2002 • 14 citations

The effect of methamphetamine on the mRNA level for 14·3·3 ⥈ chain in the human cultured cells

1995 • 11 citations

The effect of methamphetamine on the mRNA level for 14.3.3 ηchain in the human cultured cells

1996 • 1 citations