Synergism between Calcium and Cyclic GMP in Cyclic AMP Response Element-Dependent Transcriptional Regulation Requires Cooperation between CREB and C/EBP-β

Transcriptional regulation by the phosphorylation-dependent factor CREB

2001 • 2,488 citations

CREB: A Stimulus-Induced Transcription Factor Activated by A Diverse Array of Extracellular Signals

1999 • 2,076 citations

AP-1 in cell proliferation and survival

2001 • 1,686 citations

Calcium regulation of neuronal gene expression

2001 • 1,003 citations

Biological Role of the CCAAT/Enhancer-binding Protein Family of Transcription Factors

1998 • 799 citations

AP-1 in mouse development and tumorigenesis

2001 • 727 citations

Repression of the Interleukin-6 Promoter by Estrogen Receptor Is Mediated by NF-κB and C/EBPβ

1995 • 692 citations

A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro.

1991 • 604 citations

Extracellular-signal-regulated kinase signalling in neurons

1999 • 554 citations

c-JUN, JUN B, and JUN D differ in their binding affinities to AP-1 and CRE consensus sequences: effect of FOS proteins.

1991 • 543 citations

A Dominant-Negative Inhibitor of CREB Reveals that It Is a General Mediator of Stimulus-Dependent Transcription of c-fos

1998 • 502 citations

Long-Term Potentiation Is Reduced in Mice That Are Doubly Mutant in Endothelial and Neuronal Nitric Oxide Synthase

1996 • 436 citations

Intestinal Secretory Defects and Dwarfism in Mice Lacking cGMP-Dependent Protein Kinase II

1996 • 405 citations

Nitric Oxide Signaling Contributes to Late-Phase LTP and CREB Phosphorylation in the Hippocampus

1999 • 404 citations

Calcium-Regulated Phosphorylation Within the Leucine Zipper of C/EBPβ

1992 • 398 citations

cAMP stimulates the C/EBP-related transcription factor rNFIL-6 to trans-locate to the nucleus and induce c-fos transcription.

1991 • 388 citations

Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain

1993 • 345 citations

Interaction and functional collaboration of p300 and C/EBPβ

1997 • 339 citations

Phosphorylation of CBP Mediates Transcriptional Activation by Neural Activity and CaM Kinase IV

2002 • 329 citations

Regulation of c-fos expression in transgenic mice requires multiple interdependent transcription control elements

1995 • 300 citations

Amplification of calcium-induced gene transcription by nitric oxide in neuronal cells

1993 • 293 citations

Ca²⁺ regulates fluid shear-induced cytoskeletal reorganization and gene expression in osteoblasts

2000 • 291 citations

CREB Transcriptional Activity in Neurons Is Regulated by Multiple, Calcium-Specific Phosphorylation Events

2002 • 286 citations

A Dominant Negative to Activation Protein-1 (AP1) That Abolishes DNA Binding and Inhibits Oncogenesis

1997 • 285 citations

Judging a Protein by More Than Its Name: GSK-3

2001 • 281 citations

c-Myc target gene specificity is determined by a post-DNAbinding mechanism

1998 • 280 citations

Molecular events caused by mechanical stress in bone

2000 • 277 citations

C/ATF, a member of the activating transcription factor family of DNA-binding proteins, dimerizes with CAAT/enhancer-binding proteins and directs their binding to cAMP response elements.

1993 • 272 citations

Synergies and Coincidence Requirements between NO, cGMP, and Ca2+ in the Induction of Cerebellar Long-Term Depression

1997 • 264 citations

CCAAT/Enhancer-binding Proteins (C/EBP) β and δ Activate Osteocalcin Gene Transcription and Synergize with Runx2 at the C/EBP Element to Regulate Bone-specific Expression

2002 • 246 citations

Endothelial Nitric Oxide Synthase Gene-Deficient Mice Demonstrate Marked Retardation in Postnatal Bone Formation, Reduced Bone Volume, and Defects in Osteoblast Maturation and Activity

2001 • 236 citations

Natriuretic Peptide Regulation of Endochondral Ossification

1998 • 197 citations

Both the basic region and the ‘leucine zipper’ domain of the cyclic AMP response element binding (CREB) protein are essential for transcriptional activation.

1990 • 196 citations

Regulation of Activating Transcription Factor-1 and the cAMP Response Element-binding Protein by Ca2+/Calmodulin-dependent Protein Kinases Type I, II, and IV

1996 • 195 citations

Nitric oxide and cGMP analogs activate transcription from AP‐1‐responsive promoters in mammalian cells

1995 • 193 citations

Stimulation of the Cyclic GMP Pathway by NO Induces Expression of the Immediate Early Genes c‐fos and junB in PC12 Cells

1994 • 187 citations

Signalling by cGMP-dependent protein kinases

1996 • 169 citations

Presynaptic Role of cGMP-Dependent Protein Kinase during Long-Lasting Potentiation

2001 • 165 citations

Transcription factors NF-IL6 and CREB recognize a common essential site in the human prointerleukin 1 beta gene.

1994 • 156 citations

Cloning, expression, and in situ localization of rat intestinal cGMP-dependent protein kinase II.

1994 • 155 citations

Regulation of Gene Expression by cGMP-dependent Protein Kinase

1996 • 146 citations

The Biphasic Effects of Nitric Oxide in Primary Rat Osteoblasts Are cGMP Dependent

2000 • 143 citations

Molecular Characterization of a Type II Cyclic GMP‐Dependent Protein Kinase Expressed in the Rat Brain

1995 • 136 citations

Antioxidant-induced Nuclear Translocation of CCAAT/Enhancer-binding Protein β

1997 • 133 citations

Dynamic Multiphosphorylation Passwords for Activity-Dependent Gene Expression

2002 • 129 citations

Endogenous expression of type II cGMP-dependent protein kinase mRNA and protein in rat intestine. Implications for cystic fibrosis transmembrane conductance regulator.

1995 • 127 citations

The CREB family of activators is required for endochondral bone development

2001 • 123 citations

Identification and functional characterisation of the cellular activating transcription factor 43 (ATF-43) protein

1991 • 123 citations

cGMP produced in response to ANP and CNP regulates proliferation and differentiation of osteoblastic cells

1996 • 122 citations

Regulation of Gene Expression by Cyclic GMP-Dependent Protein Kinase Requires Nuclear Translocation of the Kinase: Identification of a Nuclear Localization Signal

1997 • 121 citations

Long-Term Potentiation in the Hippocampal CA1 Region of Mice Lacking cGMP-Dependent Kinases Is Normal and Susceptible to Inhibition of Nitric Oxide Synthase

1999 • 120 citations

Cyclic GMP-Dependent Protein Kinase II Plays a Critical Role in C-Type Natriuretic Peptide-Mediated Endochondral Ossification

2002 • 116 citations

PTHrP Modulates Chondrocyte Differentiation through AP-1 and CREB Signaling

2001 • 113 citations

Signal integration at the c-fos promoter

1995 • 109 citations

Transcriptional antagonist cAMP-responsive element modulator (CREM) down-regulates c-fos cAMP-induced expression.

1991 • 108 citations

Dual Regulation of Phosphorylation and Dephosphorylation of C/EBPβ Modulate Its Transcriptional Activation and DNA Binding in Response to Growth Hormone

2002 • 101 citations

Growth Hormone Regulates Phosphorylation and Function of CCAAT/Enhancer-binding Protein β by Modulating Akt and Glycogen Synthase Kinase-3

2001 • 101 citations

NO activation of fos promoter elements requires nuclear translocation of G-kinase I and CREB phosphorylation but is independent of MAP kinase activation

2000 • 95 citations

Akt pathway mediates a cGMP‐dependent survival role of nitric oxide in cerebellar granule neurones

2002 • 89 citations

Transcription Factors Oct-1 and C/EBPβ (CCAAT/Enhancer-Binding Protein-β) Are Involved in the Glutamate/Nitric Oxide/cyclic-Guanosine 5′-Monophosphate-Mediated Repression of Gonadotropin-Releasing Hormone Gene Expression

2000 • 84 citations

The cAMP Response Element Binding Protein Synergizes with Other Transcription Factors to Mediate cAMP Responsiveness

1995 • 83 citations

Nitric oxide and cGMP regulate gene expression in neuronal and glial cells by activating type II cGMP‐dependent protein kinase

1999 • 80 citations

NMDA and nitric oxide act through the cGMP signal transduction pathway to repress hypothalamic gonadotropin-releasing hormone gene expression.

1996 • 78 citations

Nitric Oxide Regulation of Gene Transcription via Soluble Guanylate Cyclase and Type I cGMP-dependent Protein Kinase

1999 • 77 citations

The helix-loop-helix protein rE12 and the C/EBP-related factor rNFIL-6 bind to neighboring sites within the c-fos serum response element.

1991 • 74 citations

Signal transduction by cGMP-dependent protein kinases and their emerging roles in the regulation of cell adhesion and gene expression

2005 • 73 citations

Endogenous Type II cGMP-dependent Protein Kinase Exists as a Dimer in Membranes and Can Be Functionally Distinguished from the Type I Isoforms

1997 • 69 citations

Expressions of CCAAT/Enhancer-binding Proteins β and δ and Their Activities Are Intensified by cAMP Signaling as Well as Ca2+/Calmodulin Kinases Activation in Hippocampal Neurons

1998 • 66 citations

cGMP-dependent Protein Kinase Iβ Physically and Functionally Interacts with the Transcriptional Regulator TFII-I

2002 • 64 citations

Nitric oxide induces c-fos gene expression via cyclic AMP response element binding protein (CREB) phosphorylation in rat retinal pigment epithelium

1995 • 53 citations

Interaction between CCAAT/Enhancer Binding Protein and Cyclic AMP Response Element Binding Protein 1 Regulates Human Immunodeficiency Virus Type 1 Transcription in Cells of the Monocyte/Macrophage Lineage

2001 • 50 citations

CCAAT/enhancer binding proteins: do they possess intrinsic cAMP-inducible activity?

2002 • 47 citations

Impaired Cyclic AMP-Dependent Phosphorylation Renders CREB a Repressor of C/EBP-Induced Transcription of the Somatostatin Gene in an Insulinoma Cell Line

1995 • 46 citations

Constitutive expression of inducible nitric oxide synthase in human bronchial epithelial cells induces c-fos and stimulates the cGMP pathway.

1994 • 44 citations

Calmodulin-dependent activation of p38 and p42/44 mitogen-activated protein kinases contributes to c-fos expression by calcium in PC12 cells: modulation by nitric oxide

2000 • 43 citations

Ras Regulates the Association of Serum Response Factor and CCAAT/Enhancer-binding Protein β

1999 • 39 citations

Prostaglandin E2-Mediated Activation of HIV-1 Long Terminal Repeat Transcription in Human T Cells Necessitates CCAAT/Enhancer Binding Protein (C/EBP) Binding Sites in Addition to Cooperative Interactions Between C/EBPβ and Cyclic Adenosine 5′-Monophosphate Response Element Binding Protein

2002 • 34 citations

The conjunctive stimuli that cause long-term desensitization also predominantly induce c-Fos and Jun-B in cerebellar Purkinje cells

1993 • 33 citations

Immediate early gene induction by natriuretic peptides in PC12 phaeochromocytoma and C6 glioma cells

1997 • 23 citations

Effect of nitric oxide synthesis inhibition on c-Fos expression in hippocampus and cerebral cortex following two forms of learning in rats

1999 • 18 citations

The Role of Prostaglandins and Nitric Oxide in the Response of Bone to Mechanical Stimulation

1997 • 12 citations