Distinct and specific functions of cGMP-dependent protein kinases

Active and Inactive Protein Kinases: Structural Basis for Regulation

1996 • 1,361 citations

The nitric oxide and cGMP signal transduction system: regulation and mechanism of action

1993 • 761 citations

Mena, a Relative of VASP and Drosophila Enabled, Is Implicated in the Control of Microfilament Dynamics

1996 • 667 citations

Guanylyl cyclase is a heat-stable enterotoxin receptor

1990 • 600 citations

Structure and Function of Cyclic Nucleotide-Dependent Protein Kinases

1994 • 442 citations

Intestinal Secretory Defects and Dwarfism in Mice Lacking cGMP-Dependent Protein Kinase II

1996 • 405 citations

The nitric oxide-cyclic GMP signalling pathway in rat brain

1993 • 341 citations

cGMP-dependent protein kinase, a chimeric protein homologous with two separate protein families

1984 • 292 citations

Cyclic GMP Causes Ca2+ Desensitization in Vascular Smooth Muscle by Activating the Myosin Light Chain Phosphatase

1997 • 263 citations

Phosphorylation of Focal Adhesion Vasodilator‐Stimulated Phosphoprotein at Ser157 in Intact Human Platelets Correlates with Fibrinogen Receptor Inhibition

1994 • 251 citations

Regulation of sarcoplasmic reticulum protein phosphorylation by localized cyclic GMP-dependent protein kinase in vascular smooth muscle cells.

1991 • 226 citations

Phosphorylation of the Inositol 1,4,5-Trisphosphate Receptor

1996 • 213 citations

Characterization of β-R1, a Gene That Is Selectively Induced by Interferon β (IFN-β) Compared with IFN-α

1996 • 181 citations

Characterization of a novel isozyme of cGMP-dependent protein kinase from bovine aorta

1989 • 158 citations

(Rp)-8-pCPT-cGMPS, a novel cGMP-dependent protein kinase inhibitor

1994 • 156 citations

VASP interaction with vinculin: a recurring theme of interactions with proline‐rich motifs

1996 • 152 citations

Regulation of Gene Expression by cGMP-dependent Protein Kinase

1996 • 146 citations

Isotype-specific Activation of Cystic Fibrosis Transmembrane Conductance Regulator-Chloride Channels by cGMP-dependent Protein Kinase II

1995 • 140 citations

Molecular Characterization of a Type II Cyclic GMP‐Dependent Protein Kinase Expressed in the Rat Brain

1995 • 136 citations

Protein Phosphatase 2A Is Essential for the Activation of Ca2+-activated K+ Currents by cGMP-dependent Protein Kinase in Tracheal Smooth Muscle and Chinese Hamster Ovary Cells

1996 • 135 citations

Site‐specific phosphorylation of the purified receptor for calcium‐channel blockers by cAMP‐ and cGMP‐dependent protein kinases, protein kinase C, calmodulin‐dependent protein kinase II and casein kinase II

1988 • 131 citations

Structure and physiological role of cGMP-dependent protein kinase

1992 • 130 citations

Endogenous expression of type II cGMP-dependent protein kinase mRNA and protein in rat intestine. Implications for cystic fibrosis transmembrane conductance regulator.

1995 • 127 citations

Determination of Cyclic Nucleotide-Dependent Protein Kinase Substrate Specificity by the Use of Peptide Libraries on Cellulose Paper

1995 • 123 citations

Expression of cGMP-Dependent Protein Kinase I and Phosphorylation of Its Substrate, Vasodilator-Stimulated Phosphoprotein, in Human Endothelial Cells of Different Origin

1995 • 122 citations

Guanylin: a peptide regulator of epithelial transport ¹

1995 • 114 citations

Interaction of Shc with Adaptor Protein Adaptins

1996 • 114 citations

Guanosine 3',5'-cyclic monophosphate-dependent protein kinase II mediates heat-stable enterotoxin-provoked chloride secretion in rat intestine

1997 • 106 citations

The Type II Isoform of cGMP-dependent Protein Kinase Is Dimeric and Possesses Regulatory and Catalytic Properties Distinct from the Type I Isoforms

1995 • 103 citations

Effects of cGMP-dependent phosphorylation on rat and human connexin43 gap junction channels

1995 • 102 citations

cGMP Signaling through cAMP- and cGMP-Dependent Protein Kinases

1995 • 98 citations

Regulation of CFTR channel gating

1994 • 95 citations

N-terminal Myristoylation Is Required for Membrane Localization of cGMP-dependent Protein Kinase Type II

1996 • 93 citations

A specific substrate from rabbit cerebellum for guanosine-3‘:5‘-monophosphate-dependent protein kinase. III. Amino acid sequences at the two phosphorylation sites.

1981 • 88 citations

cGMP Stimulation of Cystic Fibrosis Transmembrane Conductance Regulator Cl− Channels Co-expressed with cGMP-dependent Protein Kinase Type II but Not Type Iβ

1997 • 88 citations

Autophosphorylation of Type Iβ cGMP-dependent Protein Kinase Increases Basal Catalytic Activity and Enhances Allosteric Activation by cGMP or cAMP

1996 • 84 citations

Expression of type II cGMP-dependent protein kinase in rat kidney is regulated by dehydration and correlated with renin gene expression.

1996 • 83 citations

Atrial Natriuretic Peptide Induces the Expression of MKP-1, a Mitogen-activated Protein Kinase Phosphatase, in Glomerular Mesangial Cells

1996 • 79 citations

NMDA and nitric oxide act through the cGMP signal transduction pathway to repress hypothalamic gonadotropin-releasing hormone gene expression.

1996 • 78 citations

Endogenous Type II cGMP-dependent Protein Kinase Exists as a Dimer in Membranes and Can Be Functionally Distinguished from the Type I Isoforms

1997 • 69 citations

High-Affinity Binding and Localization of the Cyclic GMP-Dependent Protein Kinase with the Intermediate Filament Protein Vimentin

1994 • 63 citations

Fast and Slow Cyclic Nucleotide-dissociation Sites in cAMP-dependent Protein Kinase Are Transposed in Type Iβ cGMP-dependent Protein Kinase

1996 • 54 citations

Expression, purification, and characterization of the cGMP‐dependent protein kinases Iβ and II using the baculovirus system

1995 • 54 citations

Effects of cyclic GMP on the secondary structure of cyclic GMP dependent protein kinase and an analysis of the enzymes and amino-terminal domain by far-ultraviolet circular dichroism

1990 • 48 citations

Effect of Cyclic GMP on Intestinal Transport

1994 • 47 citations

Biochemical Properties and Cellular Localization of the DG1 cGMP-dependent Protein Kinase

1996 • 18 citations