Dynamic Microtubules Lead the Way for Spindle Positioning

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Force Generation by Microtubule Assembly/Disassembly in Mitosis and Related Movements

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Mechanisms of asymmetric cell division: Two Bs or not two Bs, that is the question

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Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo

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KAR3, a kinesin-related gene required for yeast nuclear fusion

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Kinetochores are transported poleward along a single astral microtubule during chromosome attachment to the spindle in newt lung cells.

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A Mechanism for Nuclear Positioning in Fission Yeast Based on Microtubule Pushing

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An actin nucleation mechanism mediated by Bni1 and Profilin

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Microtubules Orient the Mitotic Spindle in Yeast through Dynein-dependent Interactions with the Cell Cortex

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The Respective Contributions of the Mother and Daughter Centrioles to Centrosome Activity and Behavior in Vertebrate Cells

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Duplication of Spindle Plaques and Integration of the Yeast Cell Cycle

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The oncoprotein 18/stathmin family of microtubule destabilizers

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Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle

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Spindle dynamics and cell cycle regulation of dynein in the budding yeast, Saccharomyces cerevisiae.

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The Kinesin-Related Protein MCAK Is a Microtubule Depolymerase that Forms an ATP-Hydrolyzing Complex at Microtubule Ends

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The Distribution of Active Force Generators Controls Mitotic Spindle Position

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A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl

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Microtubule “Plus-End-Tracking Proteins”

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tea1 and the Microtubular Cytoskeleton Are Important for Generating Global Spatial Order within the Fission Yeast Cell

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MEN and SIN: what's the difference?

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A Mechanism for Coupling Exit from Mitosis to Partitioning of the Nucleus

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Microtubule Interactions with the Cell Cortex Causing Nuclear Movements in Saccharomyces cerevisiae

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SAS-4 Is a C. elegans Centriolar Protein that Controls Centrosome Size

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Heterotrimeric G Proteins Direct Two Modes of Asymmetric Cell Division in the Drosophila Nervous System

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The Bub2p Spindle Checkpoint Links Nuclear Migration with Mitotic Exit

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Myosin V orientates the mitotic spindle in yeast

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Translation of Polarity Cues into Asymmetric Spindle Positioning in Caenorhabditis elegans Embryos

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Astral Microtubule Dynamics in Yeast: A Microtubule-based Searching Mechanism for Spindle Orientation and Nuclear Migration into the Bud

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Polarization of theC. eleganszygote proceeds via distinct establishment and maintenance phases

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Dynamic instability of microtubules is regulated by force

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Positioning of the Mitotic Spindle by a Cortical-Microtubule Capture Mechanism

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Yeast Kar3 is a minus-end microtubule motor protein that destabilizes microtubules preferentially at the minus ends.

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CLIP170-like tip1p Spatially Organizes Microtubular Dynamics in Fission Yeast

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Mitosis: a history of division

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Disruption of the Diaphanous-Related Formin Drf1 Gene Encoding mDia1 Reveals a Role for Drf3 as an Effector for Cdc42

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Distinct roles for Gα and Gβγ in regulating spindle position and orientation in Caenorhabditis elegans embryos

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Determinants of S. cerevisiae Dynein Localization and Activation

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Asymmetric Loading of Kar9 onto Spindle Poles and Microtubules Ensures Proper Spindle Alignment

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Yeast Bim1p Promotes the G1-specific Dynamics of Microtubules

1999 • 248 citations

Structural changes accompanying GTP hydrolysis in microtubules: information from a slowly hydrolyzable analogue guanylyl-(alpha,beta)-methylene-diphosphonate.

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A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function inC. elegans

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Asymmetrically Distributed C. elegans Homologs of AGS3/PINS Control Spindle Position in the Early Embryo

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Dynamic instability of microtubules as an efficient way to search in space.

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A role for regulated binding of p150Glued to microtubule plus ends in organelle transport

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Surfing on microtubule ends

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Polymer Motors: Pushing out the Front and Pulling up the Back

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SAS-4 Is Essential for Centrosome Duplication in C. elegans and Is Recruited to Daughter Centrioles Once per Cell Cycle

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Mal3, the Fission Yeast Homologue of the Human APC-interacting Protein EB-1 Is Required for Microtubule Integrity and the Maintenance of Cell Form

1997 • 215 citations

Assembly and positioning of microtubule asters in microfabricated chambers

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XMAP from Xenopus eggs promotes rapid plus end assembly of microtubules and rapid microtubule polymer turnover.

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A Formin Homology Protein and a Profilin Are Required for Cytokinesis and Arp2/3-Independent Assembly of Cortical Microfilaments in C. elegans

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Molecular Linkage Underlying Microtubule Orientation Toward Cortical Sites in Yeast

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Mode of centriole duplication and distribution.

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Spindle orientation in Saccharomyces cerevisiae depends on the transport of microtubule ends along polarized actin cables

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Minus-end-directed motion of kinesin–coated microspheres driven by microtubule depolymerization

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EB1 Targets to Kinetochores with Attached, Polymerizing Microtubules

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Polarization of the anterior–posterior axis of C. elegans is a microtubule-directed process

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Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6

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ZYG-9, A Caenorhabditis elegans Protein Required for Microtubule Organization and Function, Is a Component of Meiotic and Mitotic Spindle Poles

1998 • 173 citations

The free energy for hydrolysis of a microtubule-bound nucleotide triphosphate is near zero: all of the free energy for hydrolysis is stored in the microtubule lattice [published erratum appears in J Cell Biol 1995 Apr;129(2):549]

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The Cytoplasmic Dynein and Kinesin Motors Have Interdependent Roles in Patterning the Drosophila Oocyte

2002 • 159 citations

The Cortical Protein Num1p Is Essential for Dynein-Dependent Interactions of Microtubules with the Cortex

2000 • 157 citations

PARP-3 localizes preferentially to the daughter centriole and interferes with the G1/S cell cycle progression

2003 • 157 citations

Microtubule capture by the cleavage apparatus is required for proper spindle positioning in yeast

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Control of Microtubule Dynamics by Stu2p Is Essential for Spindle Orientation and Metaphase Chromosome Alignment in Yeast

2001 • 155 citations

Bim1p/Yeb1p Mediates the Kar9p-dependent Cortical Attachment of Cytoplasmic Microtubules

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Yeast Cdk1 translocates to the plus end of cytoplasmic microtubules to regulate bud cortex interactions

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The spd-2 gene is required for polarization of the anteroposterior axis and formation of the sperm asters in the Caenorhabditis elegans zygote

2000 • 153 citations

Dynamic Positioning of Mitotic Spindles in Yeast:

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TAC-1 and ZYG-9 Form a Complex that Promotes Microtubule Assembly in C. elegans Embryos

2003 • 141 citations

Control of cell polarity and mitotic spindle positioning in animal cells

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Tea2p Is a Kinesin-like Protein Required to Generate Polarized Growth in Fission Yeast

2000 • 138 citations

Regulation of the Mitotic Exit Protein Kinases Cdc15 and Dbf2

2001 • 135 citations

Regulation of the Bfa1p–Bub2p complex at spindle pole bodies by the cell cycle phosphatase Cdc14p

2002 • 135 citations

Fission yeast mod5p regulates polarized growth through anchoring of tea1p at cell tips

2003 • 135 citations

XMAP215: a key component of the dynamic microtubule cytoskeleton

2002 • 129 citations

A Role for RIC-8 (Synembryn) and GOA-1 (Goα) in Regulating a Subset of Centrosome Movements During Early Embryogenesis in Caenorhabditis elegans

2000 • 128 citations

Targeted movement of cell end factors in fission yeast

2003 • 125 citations

Stu2 Promotes Mitotic Spindle Elongation in Anaphase

2001 • 122 citations

Stu2p, the budding yeast member of the conserved Dis1/XMAP215 family of microtubule-associated proteins is a plus end–binding microtubule destabilizer

2003 • 122 citations

TAC-1, a Regulator of Microtubule Length in the C. elegans Embryo

2003 • 118 citations

Role of bud6p and tea1p in the interaction between actin and microtubules for the establishment of cell polarity in fission yeast

2001 • 117 citations

Cortical Num1p Interacts with the Dynein Intermediate Chain Pac11p and Cytoplasmic Microtubules in Budding Yeast

2001 • 115 citations

Caenorhabditis elegans TAC-1 and ZYG-9 Form a Complex that Is Essential for Long Astral and Spindle Microtubules

2003 • 110 citations

A Metastable Intermediate State of Microtubule Dynamic Instability That Differs Significantly between Plus and Minus Ends

1997 • 107 citations

Identification of XMAP215 as a microtubule-destabilizing factor in Xenopus egg extract by biochemical purification

2003 • 104 citations

Anucleate Caenorhabditis elegans sperm can crawl, fertilize oocytes and direct anterior-posterior polarization of the 1-cell embryo

2000 • 101 citations

Searching for the middle ground

2002 • 101 citations

PAR Proteins Regulate Microtubule Dynamics at the Cell Cortex in C. elegans

2003 • 97 citations

Posterior Localization of Dynein and Dorsal-Ventral Axis Formation Depend on Kinesin in Drosophila Oocytes

2002 • 95 citations

Roles of fission yeast tea1p in the localization of polarity factors and in organizing the microtubular cytoskeleton

2002 • 95 citations

The Differential Roles of Budding Yeast Tem1p, Cdc15p, and Bub2p Protein Dynamics in Mitotic Exit

2004 • 93 citations

Mechanisms of spindle positioning: focus on flies and worms

2002 • 92 citations

PAR-dependent and geometry-dependent mechanisms of spindle positioning

2003 • 89 citations

The Surveillance Mechanism of the Spindle Position Checkpoint in Yeast

2001 • 88 citations

Exit from Mitosis

2000 • 86 citations

The Anaphase-Promoting Complex and Separin Are Required for Embryonic Anterior-Posterior Axis Formation

2002 • 85 citations

XMAP215 regulates microtubule dynamics through two distinct domains

2001 • 84 citations

Dynamics of microtubule asters in microfabricated chambers: The role of catastrophes

2002 • 83 citations

Microtubule Dynamics from Mating through the First Zygotic Division in the Budding Yeast Saccharomyces cerevisiae

1999 • 82 citations

Spindles cotton on to junctions, APC and EB1

2001 • 72 citations

The Minus End-Directed Motor Kar3 Is Required for Coupling Dynamic Microtubule Plus Ends to the Cortical Shmoo Tip in Budding Yeast

2003 • 71 citations

Nuclear migration in Saccbaromyces cerevisiae is controlled by the highly repetitive 313 kDa NUM1 protein

1991 • 70 citations

The mechanism of kinetochore-spindle attachment and polewards movement analyzed in PtK2 cells at the prophase-prometaphase transition.

1990 • 68 citations

β-Tubulin C354 Mutations that Severely Decrease Microtubule Dynamics Do Not Prevent Nuclear Migration in Yeast

2002 • 66 citations

Coordinated Spindle Assembly and Orientation Requires Clb5p-Dependent Kinase in Budding Yeast

2000 • 61 citations

The maternal genespn-4encodes a predicted RRM protein required for mitotic spindle orientation and cell fate patterning in earlyC. elegansembryos

2001 • 59 citations

Mutations in a β-Tubulin Disrupt Spindle Orientation and Microtubule Dynamics in the EarlyCaenorhabditis elegansEmbryo

2003 • 52 citations

TheSaccharomyces cerevisiaeSpindle Pole Body Is a Dynamic Structure

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Kar9p-independent Microtubule Capture at Bud6p Cortical Sites Primes Spindle Polarity before Bud Emergence inSaccharomyces cerevisiae

2002 • 37 citations

Nuclear and Spindle Dynamics in Budding Yeast

1998 • 37 citations

Spindle Polarity inS. cerevisiae: MEN Can Tell

2002 • 13 citations