Disruption of the Diaphanous-Related Formin Drf1 Gene Encoding mDia1 Reveals a Role for Drf3 as an Effector for Cdc42

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

Multiple sequence alignment with Clustal X

1998 • 2,667 citations

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.

1993 • 2,370 citations

Partitioning of Lipid-Modified Monomeric GFPs into Membrane Microdomains of Live Cells

2002 • 2,231 citations

The Ras-Related Protein Cdc42Hs and Bradykinin Promote Formation of Peripheral Actin Microspikes and Filopodia in Swiss 3T3 Fibroblasts

1995 • 1,033 citations

Integrin-Mediated Activation of Cdc42 Controls Cell Polarity in Migrating Astrocytes through PKCζ

2001 • 1,004 citations

Cooperation between mDia1 and ROCK in Rho-induced actin reorganization

1999 • 884 citations

Actions of cytochalasins on the organization of actin filaments and microtubules in a neuronal growth cone.

1988 • 851 citations

Antagonism between Ena/VASP Proteins and Actin Filament Capping Regulates Fibroblast Motility

2002 • 828 citations

p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

1997 • 819 citations

Role of Formins in Actin Assembly: Nucleation and Barbed-End Association

2002 • 740 citations

Autoinhibition and activation mechanisms of the Wiskott–Aldrich syndrome protein

2000 • 739 citations

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

1998 • 656 citations

Bni1p, a Yeast Formin Linking Cdc42p and the Actin Cytoskeleton During Polarized Morphogenesis

1997 • 654 citations

A Conserved Binding Motif Defines Numerous Candidate Target Proteins for Both Cdc42 and Rac GTPases

1995 • 625 citations

WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell mov

2001 • 594 citations

mDia mediates Rho-regulated formation and orientation of stable microtubules

2001 • 566 citations

Cellular Control of Actin Nucleation

2002 • 507 citations

An actin nucleation mechanism mediated by Bni1 and Profilin

2002 • 475 citations

Nonsyndromic Deafness DFNA1 Associated with Mutation of a Human Homolog of the Drosophila Gene diaphanous

1997 • 409 citations

Regulated Actin Cytoskeleton Assembly at Filopodium Tips Controls Their Extension and Retraction

1999 • 408 citations

diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene

1994 • 408 citations

Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex

2001 • 404 citations

Diaphanous-Related Formins Bridge Rho GTPase and Src Tyrosine Kinase Signaling

2000 • 379 citations

N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility

2001 • 338 citations

Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization

2001 • 335 citations

Identification of a Carboxyl-terminal Diaphanous-related Formin Homology Protein Autoregulatory Domain

2001 • 322 citations

Nerve growth cone lamellipodia contain two populations of actin filaments that differ in organization and polarity.

1992 • 305 citations

Bni1p implicated in cytoskeletal control is a putative target of Rho1p small GTP binding protein in Saccharomyces cerevisiae.

1996 • 284 citations

WIP regulates N-WASP-mediated actin polymerization and filopodium formation

2001 • 280 citations

A Human Homologue of the Drosophila melanogaster diaphanous Gene Is Disrupted in a Patient with Premature Ovarian Failure: Evidence for Conserved Function in Oogenesis and Implications for Human Sterility

1998 • 251 citations

Roles of the fission yeast formin for3p in cell polarity, actin cable formation and symmetric cell division

2001 • 249 citations

Analysis of RhoA-binding Proteins Reveals an Interaction Domain Conserved in Heterotrimeric G Protein β Subunits and the Yeast Response Regulator Protein Skn7

1998 • 208 citations

FH proteins as cytoskeletal organizers

1998 • 195 citations

The Diaphanous-related Formin mDia1 Controls Serum Response Factor Activity through its Effects on Actin Polymerization

2002 • 188 citations

GFP imaging: methodology and application to investigate cellular compartmentation in plants

2001 • 185 citations

Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity

2001 • 184 citations

Rho1p-Bni1p-Spa2p Interactions: Implication in Localization of Bni1p at the Bud Site and Regulation of the Actin Cytoskeleton inSaccharomyces cerevisiae

1998 • 168 citations

Distinct Actions and Cooperative Roles of ROCK and mDia in Rho Small G Protein-induced Reorganization of the Actin Cytoskeleton in Madin–Darby Canine Kidney Cells

1999 • 165 citations

Dynamic Localization and Function of Bni1p at the Sites of Directed Growth in Saccharomyces cerevisiae

2001 • 153 citations

A Novel Neural Wiskott-Aldrich Syndrome Protein (N-Wasp) Binding Protein, Wish, Induces Arp2/3 Complex Activation Independent of Cdc42

2001 • 147 citations

Localization of a mammalian homolog of diaphanous, mDia1, to the mitotic spindle in HeLa cells

2001 • 124 citations

Effect of capping protein on the kinetics of actin polymerization

1985 • 108 citations

The Formin/Diaphanous-related Protein, FHOS, Interacts with Rac1 and Activates Transcription from the Serum Response Element

2001 • 90 citations

Srf-/- ES cells display non-cell-autonomous impairment in mesodermal differentiation

2000 • 89 citations

mDia-interacting Protein Acts Downstream of Rho-mDia and Modifies Src Activation and Stress Fiber Formation

2001 • 85 citations

Rho Small G-Protein-Dependent Binding of mDia to an Src Homology 3 Domain-Containing IRSp53/BAIAP2

2000 • 80 citations

Interaction of Rho1p target Bni1p with F-actin-binding elongation factor 1α: implication in Rho1p-regulated reorganization of the actin cytoskeleton in Saccharomyces cerevisiae

1998 • 68 citations

Efficient expression of miniprep plasmid DNA after needle micro-injection into somatic cells.

1993 • 31 citations

Rho, Rac and Cdc42

1999 • 3 citations