TAC-1 and ZYG-9 Form a Complex that Promotes Microtubule Assembly in C. elegans Embryos

THE GENETICS OF CAENORHABDITIS ELEGANS

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Dynamic instability of microtubule growth

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Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans

2001 • 1,779 citations

Creation of Low-Copy Integrated Transgenic Lines in Caenorhabditis elegans

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Cytoplasmic Dynein Is Required for Distinct Aspects of Mtoc Positioning, Including Centrosome Separation, in the One Cell Stage Caenorhabditis elegans Embryo

1999 • 443 citations

MOR1 is essential for organizing cortical microtubules in plants

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Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans

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A microtubule-associated protein from Xenopus eggs that specifically promotes assembly at the plus-end.

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Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules

2002 • 324 citations

Centrosome Maturation and Mitotic Spindle Assembly in C. elegans Require SPD-5, a Protein with Multiple Coiled-Coil Domains

2002 • 280 citations

Msps/XMAP215 interacts with the centrosomal protein D-TACC to regulate microtubule behaviour

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The TACC domain identifies a family of centrosomal proteins that can interact with microtubules

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Dynamic instability of microtubules as an efficient way to search in space.

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Spindle Dynamics and the Role of γ-Tubulin in EarlyCaenorhabditis elegansEmbryos

2001 • 220 citations

The kinetically dominant assembly pathway for centrosomal asters in Caenorhabditis elegans is γ-tubulin dependent

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Reconstitution of Physiological Microtubule Dynamics Using Purified Components

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XMAP from Xenopus eggs promotes rapid plus end assembly of microtubules and rapid microtubule polymer turnover.

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D-TACC: a novel centrosomal protein required for normal spindle function in the early Drosophila embryo

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ZYG-9, A Caenorhabditis elegans Protein Required for Microtubule Organization and Function, Is a Component of Meiotic and Mitotic Spindle Poles

1998 • 173 citations

Dissection of Cell Division Processes in the One Cell Stage Caenorhabditis elegans Embryo by Mutational Analysis

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The roles of Fzy/Cdc20 and Fzr/Cdh1 in regulating the destruction of cyclin B in space and time

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Differential Activation of the DNA Replication Checkpoint Contributes to Asynchrony of Cell Division in C. elegans Embryos

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mini spindles

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Msps protein is localized to acentrosomal poles to ensure bipolarity of Drosophila meiotic spindles

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Control of Microtubule Dynamics by Stu2p Is Essential for Spindle Orientation and Metaphase Chromosome Alignment in Yeast

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XMAP215: a key component of the dynamic microtubule cytoskeleton

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Centrosomes and cancer

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Centrosomes and cancer: lessons from a TACC

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Identification of XMAP215 as a microtubule-destabilizing factor in Xenopus egg extract by biochemical purification

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zyg-8, a Gene Required for Spindle Positioning in C. elegans, Encodes a Doublecortin-Related Kinase that Promotes Microtubule Assembly

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XMAP215 regulates microtubule dynamics through two distinct domains

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Two loci required for cytoplasmic organization in early embryos of Caenorhabditis elegans

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Centrosomal TACCtics

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Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells

2002 • 47 citations

Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells

2002 • 27 citations