Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

Effects of cytochalasin and phalloidin on actin.

1987 • 1,989 citations

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

1999 • 1,558 citations

Rho GTPases Control Polarity, Protrusion, and Adhesion during Cell Movement

1999 • 1,452 citations

Matrix-dependent Tiam1/Rac Signaling in Epithelial Cells Promotes Either Cell–Cell Adhesion or Cell Migration and Is Regulated by Phosphatidylinositol 3-Kinase

1998 • 667 citations

Overexpression of the Dynamitin (p50) Subunit of the Dynactin Complex Disrupts Dynein-dependent Maintenance of Membrane Organelle Distribution

1997 • 652 citations

Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis.

1996 • 634 citations

mDia mediates Rho-regulated formation and orientation of stable microtubules

2001 • 566 citations

Distinct populations of microtubules: Tyrosinated and nontyrosinated alpha tubulin are distributed differently in vivo

1984 • 532 citations

Microtubules Orient the Mitotic Spindle in Yeast through Dynein-dependent Interactions with the Cell Cortex

1997 • 468 citations

A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function

2000 • 432 citations

GRASP65, a Protein Involved in the Stacking of Golgi Cisternae

1997 • 415 citations

Polarization of the Golgi apparatus and the microtubule-organizing center in cultured fibroblasts at the edge of an experimental wound.

1982 • 403 citations

Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42.

1995 • 386 citations

Identification of a Carboxyl-terminal Diaphanous-related Formin Homology Protein Autoregulatory Domain

2001 • 322 citations

Microtubule Interactions with the Cell Cortex Causing Nuclear Movements in Saccharomyces cerevisiae

2000 • 321 citations

Selective stabilization of microtubules oriented toward the direction of cell migration.

1988 • 296 citations

Kinesin Is a Candidate for Cross-bridging Microtubules and Intermediate Filaments

1998 • 283 citations

Mammalian Spindle Orientation and Position Respond to Changes in Cell Shape in a Dynein-dependent Fashion

2000 • 261 citations

Rho Guanosine Triphosphatase Mediates the Selective Stabilization of Microtubules Induced by Lysophosphatidic Acid

1998 • 257 citations

Dynein- and Microtubule-Mediated Translocation of Adenovirus Serotype 5 Occurs after Endosomal Lysis

2000 • 256 citations

Dynein and dynactin are localized to astral microtubules and at cortical sites in mitotic epithelial cells

1998 • 249 citations

Distribution of microtubule organizing centers in migrating sheets of endothelial cells.

1981 • 238 citations

Colocalization of cytoplasmic dynein with dynactin and CLIP-170 at microtubule distal ends

1999 • 215 citations

The dynactin complex is required for cleavage plane specification in early Caenorhabditis elegans embryos

1998 • 195 citations

Membrane insertion at the leading edge of motile fibroblasts.

1983 • 192 citations

Differential phosphorylation in vivo of cytoplasmic dynein associated with anterogradely moving organelles.

1994 • 180 citations

Centrosome positioning and directionality of cell movements

1997 • 145 citations

Detyrosinated (Glu) microtubules are stabilized by an ATP-sensitive plus-end cap

2000 • 129 citations

Microtubule-organizing centers and cell migration: effect of inhibition of migration and microtubule disruption in endothelial cells.

1983 • 111 citations

Induction of stable microtubules in 3T3 fibroblasts by TGF-β and serum

1994 • 75 citations

Reorientation of the golgi apparatus and the microtubule‐organizing center inside macrophages subjected to a chemotactic gradient

1985 • 69 citations

Regulation of Rac and Cdc42 Pathways by Gi during Lysophosphatidic Acid-induced Cell Spreading

2001 • 56 citations

Distribution of detyrosinated microtubules in motile NRK fibroblasts is rapidly altered upon cell‐cell contact: Implications for contact inhibition of locomotion

1992 • 43 citations

Depletion of lysophosphatidic acid triggers a loss of oriented detyrosinated microtubules in motile fibroblasts

1996 • 30 citations

Two effects of lysophosphatidic acid on Ca2+-movement in cultured bovine adrenal chromaffin cells

1996 • 5 citations