Lymphotoxin pathway directs thymic Aire expression

Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein

2002 • 2,371 citations

An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

1997 • 1,155 citations

Chemokines and Cell Migration in Secondary Lymphoid Organs

1999 • 1,046 citations

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self

2001 • 1,043 citations

The Lymphotoxin-β Receptor Induces Different Patterns of Gene Expression via Two NF-κB Pathways

2002 • 891 citations

Expression of relB is required for the development of thymic medulla and dendritic cells

1995 • 794 citations

Aire regulates negative selection of organ-specific T cells

2003 • 789 citations

The Lymphotoxin β Receptor Controls Organogenesis and Affinity Maturation in Peripheral Lymphoid Tissues

1998 • 710 citations

DEVELOPMENT AND MATURATION OF SECONDARY LYMPHOID TISSUES

1999 • 636 citations

Lymphotoxin-alpha-deficient mice. Effects on secondary lymphoid organ development and humoral immune responsiveness.

1995 • 436 citations

Two Pathways to NF-κB

2002 • 383 citations

The Ligands and Receptors of the Lymphotoxin System

1995 • 262 citations

Normal Thymic Architecture and Negative Selection Are Associated with Aire Expression, the Gene Defective in the Autoimmune-Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED)

2000 • 261 citations

RelB is required for Peyer's patch development: differential regulation of p52-RelB by lymphotoxin and TNF

2002 • 213 citations

Cutting Edge: Thymocyte-Independent and Thymocyte-Dependent Phases of Epithelial Patterning in the Fetal Thymus

2002 • 195 citations

RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse

2000 • 185 citations

Autoimmune polyendocrinopathy – candidosis – ectodermal dystrophy (APECED): autosomal recessive inheritance

1985 • 180 citations

Characterization of lymphotoxin-alpha beta complexes on the surface of mouse lymphocytes.

1997 • 175 citations

Gene defect behind APECED: a new clue to autoimmunity

1998 • 154 citations

Both the lymphotoxin and tumor necrosis factor pathways are involved in experimental murine models of colitis

1998 • 154 citations

Reversal of Spontaneous Autoimmune Insulitis in Nonobese Diabetic Mice by Soluble Lymphotoxin Receptor

2001 • 120 citations

APECED: a monogenic autoimmune disease providing new clues to self-tolerance

1998 • 99 citations

Visualization of Lymphotoxin-β and Lymphotoxin-β Receptor Expression in Mouse Embryos

2002 • 84 citations

Both multiorgan inflammation and myeloid hyperplasia in RelB-deficient mice are T cell dependent.

1996 • 83 citations

Phenotypically diverse mouse thymic stromal cell lines which induce proliferation and differentiation of hematopoietic cells

1993 • 74 citations

Characterization of Regulatory Elements and Methylation Pattern of the Autoimmune Regulator (AIRE) Promoter

2003 • 63 citations

A Critical Role for Lymphotoxin-β Receptor in the Development of Diabetes in Nonobese Diabetic Mice

2001 • 56 citations

Expression of lymphotoxin-beta (LT-?) in chronic inflammatory conditions

2002 • 35 citations

A thymic epithelial cell line induces both positive and negative selection in the thymus

1994 • 29 citations

Increased Thymic B Cells but Maintenance of Thymic Structure, T Cell Differentiation and Negative Selection in Lymphotoxin-α and TNF Gene-Targeted Mice

2000 • 19 citations