APECED: a monogenic autoimmune disease providing new clues to self-tolerance

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

1997 • 2,100 citations

Positional cloning of the APECED gene

1997 • 1,385 citations

An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

1997 • 1,155 citations

Clinical Variation of Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy (APECED) in a Series of 68 Patients

1990 • 1,041 citations

The PHD finger: Implications for chromatin-mediated transcriptional regulation

1995 • 857 citations

Evolution of the nuclear receptor superfamily: early diversification from an ancestral orphan receptor

1997 • 543 citations

21-hydroxylase, a major autoantigen in idiopathic Addison's disease

1992 • 403 citations

An autosomal locus causing autoimmune disease: autoimmune polyglandular disease type I assigned to chromosome 21

1994 • 379 citations

Polyglandular autoimmune syndrome type I among Iranian Jews.

1992 • 308 citations

The orphan nuclear receptor NGFI-B regulates expression of the gene encoding steroid 21-hydroxylase.

1993 • 243 citations

Identification by molecular cloning of an autoantigen associated with Addison's disease as steroid 17α-hydroxylase

1992 • 201 citations

Autoantibodies to cytochrome P450 enzymes P450scc, P450c17, and P450c21 in autoimmune polyglandular disease types I and II and in isolated Addison's disease.

1994 • 182 citations

Autoimmune polyendocrinopathy – candidosis – ectodermal dystrophy (APECED): autosomal recessive inheritance

1985 • 180 citations

T Cell-Mediated Maintenance of Natural Self-Tolerance: its Breakdown as a Possible Cause of Various Autoimmune Diseases

1996 • 175 citations

The major dermatomyositis‐specific mi‐2 autoantigen is a presumed helicase involved in transcriptional activation

1995 • 140 citations

Antibodies to glutamic acid decarboxylase and insulin-dependent diabetes in patients with autoimmune polyendocrine syndrome type I.

1996 • 120 citations

Genetic homogeneity of autoimmune polyglandular disease type I.

1996 • 117 citations

Evidence for Defective Immunoregulation in the Syndrome of Familial Candidiasis Endocrinopathy

1979 • 109 citations

Differential Interaction of Nuclear Receptors with the Putative Human Transcriptional Coactivator hTIF1

1997 • 107 citations

Cytochrome P450IA2 and aromatic <scp>l</scp>‐amino acid decarboxylase are hepatic autoantigens in autoimmune polyendocrine syndrome type I

1997 • 85 citations

The Interferon (IFN)-stimulated Gene Sp100 Promoter Contains an IFN-γ Activation Site and an Imperfect IFN-stimulated Response Element Which Mediate Type I IFN Inducibility

1996 • 74 citations

LYSP100-associated nuclear domains (LANDs): description of a new class of subnuclear structures and their relationship to PML nuclear bodies

1996 • 72 citations

Genes involved in T-cell receptor-mediated apoptosis of thymocytes and T-cell hybridomas

1997 • 62 citations