Characterization of Regulatory Elements and Methylation Pattern of the Autoimmune Regulator (AIRE) Promoter
Data up to Jan 2025
Total Citations Per Year
Abstract
References (27)
Molecular Cloning: A Laboratory Manual
2001 • 133,517 citations
Molecular cloning: A laboratory manual
1990 • 85,659 citations
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
1998 • 3,363 citations
CpG Islands in vertebrate genomes
1987 • 3,315 citations
A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands.
1992 • 3,099 citations
AP-1 function and regulation
1997 • 2,833 citations
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
1998 • 2,686 citations
Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein
2002 • 2,371 citations
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
1999 • 1,865 citations
Positional cloning of the APECED gene
1997 • 1,385 citations
An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains
1997 • 1,155 citations
Clinical Variation of Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy (APECED) in a Series of 68 Patients
1990 • 1,041 citations
[36] Eukaryotic gene transcription with purified components
1983 • 992 citations
The molecular biology of the CCAAT-binding factor NF-Y
1999 • 844 citations
Bisulfite genomic sequencing: systematic investigation of critical experimental parameters
2001 • 745 citations
Aire deficient mice develop multiple features of APECED phenotype and show altered immune response
2002 • 463 citations
Binding of TBP to promoters in vivo is stimulated by activators and requires Pol II holoenzyme
1999 • 457 citations
Autoimmune Regulator Is Expressed in the Cells Regulating Immune Tolerance in Thymus Medulla
1999 • 293 citations
The Autoimmune Regulator Protein Has Transcriptional Transactivating Properties and Interacts with the Common Coactivator CREB-binding Protein
2000 • 239 citations
RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse
2000 • 185 citations
Control of gene expression through regulation of the TATA-binding protein
2000 • 183 citations
Localization of the APECED protein in distinct nuclear structures
1999 • 154 citations
Subcellular Localization of the Autoimmune Regulator Protein
2001 • 127 citations
DNA Binding Specificity of the CCAAT-binding Factor CBF/NF-Y
1997 • 114 citations
Transcriptional Regulation of Rat Cyclin D1 Gene by CpG Methylation Status in Promoter Region
1999 • 84 citations
Isolation and Characterization of the MouseAireGene
1999 • 68 citations
Cytosine methylation of an Sp1 site contributes to organ-specific and cell-specific regulation of expression of the lung epithelial gene T1α
2000 • 48 citations