Physical and Functional Interaction between Two Pluripotent Proteins, the Y-box DNA/RNA-binding Factor, YB-1, and the Multivalent Zinc Finger Factor, CTCF

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

1996 • 8,994 citations

The Protein CTCF Is Required for the Enhancer Blocking Activity of Vertebrate Insulators

1999 • 1,076 citations

myc FUNCTION AND REGULATION

1992 • 790 citations

Chicken hematopoietic cells transformed by seven strains of defective avian leukemia viruses display three distinct phenotypes of differentiation

1979 • 769 citations

Control of c-myc Regulation in Normal and Neoplastic Cells

1991 • 632 citations

An Exceptionally Conserved Transcriptional Repressor, CTCF, Employs Different Combinations of Zinc Fingers To Bind Diverged Promoter Sequences of Avian and Mammalian c-myc Oncogenes

1996 • 536 citations

Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive

2000 • 439 citations

Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y box.

1988 • 432 citations

Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expression

1997 • 426 citations

Mass spectrometric approaches for the identification of gel‐separated proteins

1995 • 378 citations

A novel sequence-specific DNA binding protein which interacts with three regularly spaced direct repeats of the CCCTC-motif in the 5'-flanking sequence of the chicken c-myc gene.

1990 • 376 citations

Nucleolin and YB-1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation

2000 • 374 citations

Structural and functional properties of the evolutionarily ancient Y‐box family of nucleic acid binding proteins

1994 • 367 citations

Mammalian Krüppel-like transcription factors: more than just a pretty finger

1999 • 296 citations

CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2-5 homeobox gene pathway

1997 • 273 citations

CTCF, a Conserved Nuclear Factor Required for Optimal Transcriptional Activity of the Chicken c-myc Gene, Is an 11-Zn-Finger Protein Differentially Expressed in Multiple Forms

1993 • 271 citations

Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers

1999 • 266 citations

Maternal-specific footprints at putative CTCF sites in the H19 imprinting control region give evidence for insulator function

2000 • 255 citations

Stopped at the border: boundaries and insulators

1999 • 222 citations

Nuclear translocation of the Y‐box binding protein by ultraviolet irradiation

1997 • 195 citations

The Zinc Finger Protein CTCF Binds to the APBβ Domain of the Amyloid β-Protein Precursor Promoter

1997 • 187 citations

Transcription factor Y-box binding protein 1 binds preferentially to cisplatin-modified DNA and interacts with proliferating cell nuclear antigen.

1999 • 176 citations

Glomerular Mesangial Cell-specific Transactivation of Matrix Metalloproteinase 2 Transcription Is Mediated by YB-1

1997 • 150 citations

Structural and functional conservation at the boundaries of the chicken β-globin domain

2000 • 149 citations

A role for Y‐box proteins in cell proliferation

1995 • 143 citations

A widely expressed transcription factor with multiple DNA sequence specificity,CTCF, is localized at chromosome segment 16q22.1 within one of the smallest regions of overlap for common deletions in breast and prostate cancers

1998 • 142 citations

The Transcriptional Regulatory Protein, YB-1, Promotes Single-stranded Regions in the DRA Promoter

1995 • 134 citations

Negative Protein 1, Which Is Required for Function of the Chicken Lysozyme Gene Silencer in Conjunction with Hormone Receptors, Is Identical to the Multivalent Zinc Finger Repressor CTCF

1997 • 133 citations

Nuclear expression of YB-1 protein correlates with P-glycoprotein expression in human osteosarcoma.

1998 • 129 citations

Enhanced coexpression of YB‐1 and DNA topoisomerase II α genes in human colorectal carcinomas

1999 • 129 citations

Is nuclear expression of Y box-binding protein-1 a new prognostic factor in ovarian serous adenocarcinoma?

1999 • 118 citations

Masking of mRNA by Y‐box proteins

1996 • 118 citations

DNA binding properties of YB-1 and dbpA: binding to doublestranded, single-stranded, and abasic site containing DNAs

1991 • 113 citations

Enhanced coexpression of YB-1 and DNA topoisomerase II ? genes in human colorectal carcinomas

1999 • 113 citations

A Synergistic Interaction of Transcription Factors AP2 and YB-1 Regulates Gelatinase A Enhancer-dependent Transcription

1998 • 107 citations

Role of single‐stranded DNA regions and Y‐box proteins in transcriptional regulation of viral and cellular genes

1998 • 106 citations

Regulation of GATA-2 Phosphorylation by Mitogen-activated Protein Kinase and Interleukin-3

1995 • 101 citations

The 5′ flank of mouse H19 in an unusual chromatin conformation unidirectionally blocks enhancer–promoter communication

2000 • 96 citations

Problems and paradigms: Multifunctional proteins suggest connections between transcriptional and post‐transcriptional processes

1997 • 86 citations

Cloning and Characterization of Chicken YB-1: Regulation of Expression in the Liver

1993 • 84 citations

Involvement of a DNA Binding Protein, MDR-NF1/YB-1, in Human MDR1 Gene Expression by Actinomycin D

1994 • 80 citations

Molecular requirements for transcriptional initiation of the murine c-myc gene.

1989 • 77 citations

cDNA cloning and characterization of interleukin 2-induced genes in a cloned T helper lymphocyte.

1990 • 77 citations

Negative Transcriptional Regulation Mediated by Thyroid Hormone Response Element 144 Requires Binding of the Multivalent Factor CTCF to a Novel Target DNA Sequence

1999 • 72 citations

EFI_A/YB-1 Is a Component of Cardiac HF-1A Binding Activity and Positively Regulates Transcription of the Myosin Light-Chain 2v Gene

1995 • 70 citations

Suppression of grp78 Core Promoter Element-Mediated Stress Induction by the dbpA and dbpB (YB-1) Cold Shock Domain Proteins

1997 • 68 citations

Molecular weight abnormalities of the CTCF transcription factor: CTCF migrates aberrantly in SDS-PAGE and the size of the expressed protein is affected by the UTRs and sequences within the coding region of the CTCF gene

1997 • 62 citations

Involvement of transcription factor YB-1 in human T-cell lymphotropic virus type I basal gene expression

1994 • 60 citations

Physical and Functional Interaction between the Y-Box Binding Protein YB-1 and Human Polyomavirus JC Virus Large T Antigen

1999 • 59 citations

Transcriptional regulation of human polyomavirus JC: evidence for a functional interaction between RelA (p65) and the Y-box-binding protein, YB-1

1996 • 58 citations

WT1—more than a transcription factor?

1998 • 57 citations

Inheritance of chromatin states

1994 • 55 citations

c-myc oncogene expression in estrogen-dependent and -independent breast cancer

1993 • 53 citations

Characterisation of chicken erythroid nuclear proteins which bind to the nuclease hypersensitive regions upstream of the β^A- and β^H-globin genes

1986 • 51 citations

Interaction of YB-1 with human immunodeficiency virus type 1 Tat and TAR RNA modulates viral promoter activity

1999 • 46 citations

The Y-box Motif Mediates Redox-dependent Transcriptional Activation in Mouse Cells

1995 • 45 citations

Coupling transcription to translation: A novel site for the regulation of eukaryotic gene expression

1996 • 43 citations

CTCF Is Essential for Up‐Regulating Expression from the Amyloid Precursor Protein Promoter During Differentiation of Primary Hippocampal Neurons

1999 • 43 citations

A Y-box protein is a suppressor factor that decreases thyrotropin receptor gene expression.

1996 • 38 citations

The c-myc Story: Where we’ve been, Where we seem to be Going

1997 • 37 citations

Two nuclear factor binding domains activate expression from the human amyloid beta-protein precursor promoter.

1994 • 37 citations

Cancer genetics: Tumor suppressor meets oncogene

1999 • 35 citations

Transcription of the human immunodeficiency virus type 1 (HIV-1) promoter in central nervous system cells: effect of YB-1 on expression of the HIV-1 long terminal repeat.

1998 • 35 citations

Major Histocompatibility Class II HLA-DRα Gene Expression in Thyrocytes: Counter Regulation by the Class II Transactivator and the Thyroid Y Box Protein

1998 • 30 citations

Sequence‐specific DNA‐binding proteins which interact with (G + C)‐rich sequences flanking the chicken c‐myc gene

1986 • 23 citations

Chicken Y-box proteins chk-YB-1b and chk-YB-2 repress translation by sequence-specific interaction with single-stranded RNA

2000 • 23 citations

DNA lesion-recognizing proteins and the p53 connection.

1996 • 21 citations