Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive
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References (11)
The Protein CTCF Is Required for the Enhancer Blocking Activity of Vertebrate Insulators
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Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2
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A 5′ 2-Kilobase-Pair Region of the Imprinted Mouse H19 Gene Exhibits Exclusive Paternal Methylation throughout Development
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A widely expressed transcription factor with multiple DNA sequence specificity,CTCF, is localized at chromosome segment 16q22.1 within one of the smallest regions of overlap for common deletions in breast and prostate cancers
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Negative Transcriptional Regulation Mediated by Thyroid Hormone Response Element 144 Requires Binding of the Multivalent Factor CTCF to a Novel Target DNA Sequence
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The non-viability of uniparental mouse conceptuses correlates with the loss of the products of imprinted genes
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