Problems and paradigms: Multifunctional proteins suggest connections between transcriptional and post‐transcriptional processes

hnRNP PROTEINS AND THE BIOGENESIS OF mRNA

1993 • 1,486 citations

The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

1990 • 993 citations

CspA, the Major Cold-shock Protein of Escherichia coli, Is an RNA Chaperone

1997 • 626 citations

Major cold shock protein of Escherichia coli.

1990 • 541 citations

Distinct Binding Specificities and Functions of Higher Eukaryotic Polypyrimidine Tract-Binding Proteins

1995 • 537 citations

The pre-mRNA binding K protein contains a novel evolutionary conserved motif

1993 • 526 citations

Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing

1995 • 502 citations

Spi-1 is a putative oncogene in virally induced murine erythroleukaemias

1988 • 470 citations

Essential role for KH domains in RNA binding: Impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome

1994 • 442 citations

Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y box.

1988 • 432 citations

The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins.

1996 • 351 citations

Heterogeneous Nuclear Ribonucleoprotein K Is a Transcription Factor

1996 • 350 citations

Function of the mammalian La protein: evidence for its action in transcription termination by RNA polymerase III.

1989 • 340 citations

A cytoplasmic 57-kDa protein that is required for translation of picornavirus RNA by internal ribosomal entry is identical to the nuclear pyrimidine tract-binding protein.

1993 • 327 citations

Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex K protein.

1992 • 281 citations

A splicing-dependent regulatory mechanism that detects translation signals.

1996 • 278 citations

Sex lethal controls dosage compensation in Drosophila by a non-splicing mechanism

1997 • 265 citations

The Yeast La Protein Is Required for the 3′ Endonucleolytic Cleavage That Matures tRNA Precursors

1997 • 253 citations

DNA gyrase, CS7.4, and the cold shock response in Escherichia coli

1992 • 237 citations

THE GENETICS OF WILMS’ TUMOR—A Case of Disrupted Development

1994 • 232 citations

Multiple Single-Stranded cis Elements Are Associated with Activated Chromatin of the Human c-myc Gene In Vivo

1996 • 223 citations

Specific binding of heterogeneous ribonucleoprotein particle protein K to the human c-myc promoter, in vitro.

1993 • 220 citations

RNA binding by the Wilms tumor suppressor zinc finger proteins.

1996 • 218 citations

The RNA binding protein La influences both the accuracy and the efficiency of RNA polymerase III transcription in vitro.

1989 • 202 citations

The A1 and A1B proteins of heterogeneous nuclear ribonucleoparticles modulate 5' splice site selection in vivo.

1994 • 186 citations

Heterogeneous Nuclear Ribonucleoprotein K Is a DNA-binding Transactivator

1995 • 184 citations

Isolation of the heterogeneous nuclear RNA-ribonucleoprotein complex (hnRNP): a unique supramolecular assembly.

1984 • 177 citations

The Major Protein of Messenger Ribonucleoprotein Particles in Somatic Cells Is a Member of the Y-box Binding Transcription Factor Family

1995 • 175 citations

The WT1 Wilms' tumor suppressor gene: How much do we really know?

1996 • 168 citations

Pre-mRNA Processing and the CTD of RNA Polymerase II: The Tail That Wags the Dog?

1997 • 165 citations

Purification and cDNA cloning of HeLa cell p54^nrb, a nuclear protein with two RNA recognition motifs and extensive homology to human splicing factor PSF andDrosophilaNONA/BJ6

1993 • 163 citations

Patterns of translational regulation in the mammalian testis

1996 • 162 citations

Sequence-specific RNA Recognition by the Xenopus Y-box Proteins

1995 • 152 citations

A novel modulator domain of Ets transcription factors.

1992 • 147 citations

Patterns of translational regulation in the mammalian testis

1996 • 146 citations

La autoantigen alleviates translational repression by the 5' leader sequence of the human immunodeficiency virus type 1 mRNA

1994 • 143 citations

A role for Y‐box proteins in cell proliferation

1995 • 143 citations

The Transcriptional Regulatory Protein, YB-1, Promotes Single-stranded Regions in the DRA Promoter

1995 • 134 citations

A mouse Y box protein, MSY1, is associated with paternal mRNA in spermatocytes

1993 • 128 citations

Masking of mRNA by Y‐box proteins

1996 • 118 citations

An RNA recognition motif in Wilms' tumour protein (WT1) revealed by structural modelling

1996 • 116 citations

Transcription termination factor La is also an initiation factor for RNA polymerase III.

1996 • 109 citations

Ribonucleoprotein SS-B/La belongs to a protein family with consensus sequences for RNA-binding

1989 • 100 citations

The Transcription Factor Spi-1/PU.1 Binds RNA and Interferes with the RNA-binding Protein p54nrb

1996 • 94 citations

The Ets-related transcription factor PU.1 immortalizes erythroblasts.

1993 • 92 citations

Proteins Homologous to the Xenopus Germ Cell-Specific RNA-Binding Proteins p54/p56 Are Temporally Expressed in Mouse Male Germ Cells

1993 • 91 citations

mRNP4, a major mRNA-binding protein from Xenopus oocytes is identical to transcription factor FRG Y2.

1992 • 88 citations

The intron requirement for immunoglobulin gene expression is dependent upon the promoter

1988 • 87 citations

A nuclear translational block imposed by the HIV-1 U3 region is relieved by the Tat-TAR interaction

1990 • 86 citations

YB-1 DNA-binding protein represses interferon gamma activation of class II major histocompatibility complex genes.

1994 • 86 citations

Structure of the TFIIIA-5 S DNA complex

1992 • 85 citations

DNA binding, multimerization, and transcription stimulation by the Xenopus Y box proteins in vitro.

1992 • 80 citations

Binding of Y-box proteins to RNA: involvement of different protein domains

1994 • 73 citations

AXenopus laevisHomologue of the La Autoantigen Binds the Pyrimidine Tract of the 5′ UTR of Ribosomal Protein mRNAsin Vitro: Implication of a Protein Factor in Complex Formation

1996 • 73 citations

Nuclear degradation of nonsense mutated β-globin mRNA: a post-transcriptional mechanism to protect heterozygotes from severe clinical manifestations of β-thalassemia?

1995 • 73 citations

Gene Activity in Early Development.

1970 • 71 citations

A human protein containing a “cold shock” domain binds specifically to H-DNA upstream from the human gamma-globin genes.

1994 • 70 citations

A case of convergent evolution of nucleic acid binding modules

1996 • 69 citations

Characterization of the autoantigen La (SS-B) as a dsRNA unwinding enzyme

1997 • 68 citations

Determination of mRNA fate by different RNA polymerase II promoters.

1993 • 66 citations

Transcription and masking of mRNA in germ cells: involvement of Y-box proteins

1996 • 63 citations

Human La Protein: a Stabilizer of Histone mRNA

1997 • 61 citations

TFIIIC1 Acts through a Downstream Region To Stabilize TFIIIC2 Binding to RNA Polymerase III Promoters

1996 • 60 citations

The La antigen inhibits the activation of the interferoninducible protein kinase PKR by sequestering and unwinding double-stranded RNA

1994 • 59 citations

trans-Activation by the hnRNP K Protein Involves an Increase in RNA Synthesis from the Reporter Genes

1996 • 56 citations

Murine polypyrimidine tract binding protein. Purification, cloning, and mapping of the RNA binding domain.

1991 • 54 citations

Nucleic Acid-Binding Properties of the Xenopus Oocyte Y Box Protein mRNP3+4

1994 • 52 citations

The small RNAs of Epstein-Barr virus

1993 • 49 citations

TFIIIA: nine fingers - three hands?

1993 • 45 citations

The rat poly Pyrimidine Tract binding protein (PTB) interacts with a single-stranded DNA motif in a liver-specific enhancer

1992 • 44 citations

Enhancement of mRNA nuclear transport by promoter elements

1987 • 44 citations

Coupling transcription to translation: A novel site for the regulation of eukaryotic gene expression

1996 • 43 citations

Transcription factor IIIA (TFIIIA) in the second decade

1996 • 41 citations

The Polypyrimidine Tract Binding (PTB) Protein Interacts With Single-Stranded DNA in a Sequence-Specific Manner

1996 • 28 citations

Promoter control of translation inXenopus oocytes

1995 • 21 citations

Proteins binding to the leader of the 6.0 kb mRNA of human insulin-like growth factor 2 influence translation

1995 • 18 citations

Organization of (pre-)mRNA metabolism in the cell nucleus

1994 • 16 citations

Construction of novel antibodies by use of DNA transfection: design of plasmid vectors

1986 • 15 citations

RNA Processing: Wilms' tumour — the splicing connection?

1995 • 11 citations

hnRNP particles

1996 • 7 citations