Major Histocompatibility Class II HLA-DRα Gene Expression in Thyrocytes: Counter Regulation by the Class II Transactivator and the Thyroid Y Box Protein

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Basic Methods in Molecular Biology

1986 • 3,284 citations

Firefly luciferase gene: structure and expression in mammalian cells.

1987 • 3,088 citations

ROLE OF ABERRANT HLA-DR EXPRESSION AND ANTIGEN PRESENTATION IN INDUCTION OF ENDOCRINE AUTOIMMUNITY

1983 • 1,275 citations

In Situ Characterization of Autoimmune Phenomena and Expression of HLA Molecules in the Pancreas in Diabetic Insulitis

1985 • 935 citations

Regulation of MHC Class II Expression by Interferon-γ Mediated by the Transactivator Gene CIITA

1994 • 854 citations

Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

1993 • 828 citations

Autoimmune Thyroid Disease: Further Developments in Our Understanding*

1994 • 611 citations

Sequences and Factors: A Guide to MHC Class-II Transcription

1992 • 540 citations

REGULATION OF MHC CLASS II GENES: Lessons from a Disease

1996 • 488 citations

The p300/CBP family: integrating signals with transcription factors and chromatin

1997 • 482 citations

Regulation of Major Histocompatibility Complex Class-II Genes: X, Y and Other Letters of the Alphabet

1990 • 470 citations

Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y box.

1988 • 432 citations

MINIREVIEW: Cyclic AMP Response Element Binding Proteins: A Cornucopia of Transcription Factors

1990 • 394 citations

Mice Lacking the MHC Class II Transactivator (CIITA) Show Tissue-Specific Impairment of MHC Class II Expression

1996 • 356 citations

Basic methods in molecular biology

1987 • 322 citations

Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes.

1994 • 318 citations

Interferon-gamma induces HLA-DR expression by thyroid epithelium.

1985 • 314 citations

Antithyroid Drugs

1984 • 313 citations

Induction of Graves-like disease in mice by immunization with fibroblasts transfected with the thyrotropin receptor and a class II molecule.

1996 • 226 citations

Regulation of MHC gene expression

1993 • 215 citations

Autoimmune thyroid disease: further developments in our understanding

1994 • 196 citations

Activation of class II MHC genes requires both the X ☐ region and the class II transactivator (CIITA)

1995 • 180 citations

Molecular analysis of G1B and G3A IFNγ mutants reveals that defects in CIITA or RFX result in defective class II MHC and li gene induction

1994 • 145 citations

CCAAT box binding protein NF-Y facilitates in vivo recruitment of upstream DNA binding transcription factors.

1994 • 139 citations

The Transcriptional Regulatory Protein, YB-1, Promotes Single-stranded Regions in the DRA Promoter

1995 • 134 citations

A CT promoter element binding protein: definition of a double-strand and a novel single-strand DNA binding motif

1992 • 133 citations

Acis-acting transcription element of the c-mycgene can assume an H-DNA conformation

1989 • 94 citations

YB-1 DNA-binding protein represses interferon gamma activation of class II major histocompatibility complex genes.

1994 • 86 citations

Characterization of the 5'-flanking region of the rat thyrotropin receptor gene.

1992 • 84 citations

cDNA cloning and characterization of interleukin 2-induced genes in a cloned T helper lymphocyte.

1990 • 77 citations

Thyroid Peroxidase: Rat cDNA Sequence, Chromosomal Localization in Mouse, and Regulation of Gene Expression by Comparison to Thyroglobulin in Rat FRTL-5 Cells

1989 • 76 citations

Structure of an exophthalmos-producing factor derived from thyrotropin by partial pepsin digestion

1975 • 70 citations

Differential expression of Ia antigens by rheumatoid synovial lining cells.

1987 • 62 citations

Regulation of Major Histocompatibility Complex Class I Gene Expression in Thyroid Cells

1997 • 60 citations

Role of the cyclic adenosine 3',5'-monophosphate response element in efficient expression of the rat thyrotropin receptor promoter.

1992 • 55 citations

Characterization of the 5'-flanking region of the rat thyrotropin receptor gene

1992 • 48 citations

Induction of Rat Thyroid Cell MHC Class II Antigen by Thyrotropin and Y-Interferon*

1987 • 47 citations

Hormonal Modulation of Major Histocompatibility Complex Class I Gene Expression Involves an Enhancer A-binding Complex Consisting of Fra-2 and the p50 Subunit of NF-κB

1995 • 46 citations

Effects of γ-interferon and tumor necrosis factor α on thyroid cells: induction of class II antigen and inhibition of growth stimulation

1988 • 43 citations

HLA‐D/DR Expression on Epithelial Cells: The Finger on the Trigger?^a

1986 • 40 citations

A Y-box protein is a suppressor factor that decreases thyrotropin receptor gene expression.

1996 • 38 citations

AUTOIMMUNE THYROIDDISEASE AND THYROID CELL CLASS II MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGENS

1987 • 37 citations

Transforming growth factor beta 1 repression of the HLA-DR alpha gene is mediated by conserved proximal promoter elements.

1993 • 37 citations

Regulation of Major Histocompatibility Class II Gene Expression in FRTL-5 Thyrocytes: Opposite Effects of Interferon and Methimazole*

1998 • 37 citations

Influence of methimazole on murine thyroiditis. Evidence for immunosuppression in vivo.

1984 • 35 citations

Effects of Rat γ- and Non-γ-Interferons on the Expression of la Antigen, Growth, and Differentiated Functions of FRTL5 Cells*

1988 • 32 citations

Regulation of MHC Class II Gene Expression

1995 • 20 citations

The inhibitory effect of large doses of methimazole on iodine induced lymphocytic thyroiditis and serum anti-thyroglobulin antibody titers in BB/Wor rats

1989 • 17 citations

An ATF/CREB binding motif is required for aberrant constitutive expression of the MHC class II DRα promoter and activation by SV4O T-antigen

1992 • 16 citations