The Carboxy-Terminal Transactivation Domain of Oct-4 Acquires Cell Specificity through the POU Domain

Antibodies, a laboratory manual

1989 • 12,929 citations

Antibodies: A laboratory manual

1989 • 4,532 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Transcriptional Control Signals of a Eukaryotic Protein-Coding Gene

1982 • 1,406 citations

GAL4-VP16 is an unusually potent transcriptional activator

1988 • 1,379 citations

A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype

1988 • 998 citations

A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo

1990 • 924 citations

Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells

1996 • 860 citations

The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein

1988 • 771 citations

New type of POU domain in germ line-specific protein Oct-4

1990 • 753 citations

Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3.

1995 • 744 citations

Differential transcriptional activation by Oct-1 and Oct-2: Interdependent activation domains induce Oct-2 phosphorylation

1990 • 696 citations

Transcription activation by the adenovirus E1a protein

1989 • 667 citations

A family of octamer-specific proteins present during mouse embryogenesis: evidence for germline-specific expression of an Oct factor.

1989 • 664 citations

Oct-4 Transcription Factor Is Differentially Expressed in the Mouse Embryo during Establishment of the First Two Extraembryonic Cell Lineages Involved in Implantation

1994 • 623 citations

Oct-4: a germline-specific transcription factor mapping to the mouse t-complex.

1990 • 603 citations

Transcriptional Activation Modulated by Homopolymeric Glutamine and Proline Stretches

1994 • 598 citations

Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules

1994 • 506 citations

ATF-2 contains a phosphorylation-dependent transcriptional activation domain.

1995 • 504 citations

A human lymphoid- specific transcription factor that activates immunoglobulin genes is a homoeobox protein

1988 • 399 citations

An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity

1987 • 398 citations

The POU domain: versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain.

1995 • 391 citations

Structure and function of transcriptional activation domains

1995 • 376 citations

OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins

1995 • 374 citations

Octamania: The POU factors in murine development

1991 • 373 citations

Different activation domains stimulate transcription from remote (‘enhancer’) and proximal (‘promoter’) positions.

1992 • 359 citations

The POU domain is a bipartite DNA-binding structure

1988 • 304 citations

A B-cell coactivator of octamer-binding transcription factors

1995 • 301 citations

POU domain transcription factors

1993 • 278 citations

Cloning, Functional Characterization, and Mechanism of Action of the B-Cell-Specific Transcriptional Coactivator OCA-B

1995 • 273 citations

A novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors

1992 • 272 citations

Promoter-selective activation domains in Oct-1 and Oct-2 direct differential activation of an snRNA and mRNA promoter

1992 • 225 citations

High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors.

1995 • 224 citations

Control of c-Jun activity by interaction of a cell-specific inhibitor with regulatory domain δ: Differences between v- and c-Jun

1990 • 212 citations

Variable Effects of Phosphorylation of Pit-1 Dictated by the DNA Response Elements

1991 • 206 citations

A nexus between Oct-4 and E1 A: Implications for gene regulation in embryonic stem cells

1991 • 188 citations

Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cells.

1990 • 146 citations

Eukaryotic expression vectors for the analysis of mutant proteins

1989 • 126 citations

Intramolecular inhibition of activating transcription factor-2 function by its DNA-binding domain.

1996 • 118 citations

Twin of I-POU: A two amino acid difference in the I-POU homeodomain distinguishes an activator from an inhibitor of transcription

1992 • 113 citations

Down-regulation of the POU transcription factor SCIP is an early event in oligodendrocyte differentiation in vitro

1992 • 112 citations

Targeted Degradation of c-Fos, But Not v-Fos, by a Phosphorylation-Dependent Signal on c-Jun

1992 • 110 citations

Retinoic acid-mediated down-regulation of Oct3/4 coincides with the loss of promoter occupancy in vivo.

1996 • 101 citations

Structure, expression and chromosomal location of the Oct-4 gene

1991 • 100 citations

Functional Interaction between the POU Domain Protein Tst-1/Oct-6 and the High-Mobility-Group Protein HMG-I/Y

1995 • 94 citations

Regulation of theOct-4gene by nuclear receptors

1994 • 89 citations

Regulation of JC virus by the POU-domain transcription factor Tst-1: implications for progressive multifocal leukoencephalopathy.

1993 • 89 citations

Differential positive control by Oct-1 and Oct-2: activation of a transcriptionally silent motif through Oct-1 and VP16 corecruitment.

1993 • 88 citations

v-Src and EJ Ras alleviate repression of c-Jun by a cell-specific inhibitor

1991 • 81 citations

The Oct-2 glutamine-rich and proline-rich activation domains can synergize with each other or duplicates of themselves to activate transcription.

1994 • 70 citations

Cis-acting elements involved in the regulated expression of a human hsp70 gene

1988 • 67 citations

Differential transactivation potential of Oct1 and Oct2 is determined by additional B cell-specific activities.

1994 • 66 citations

Oct2 Transactivation from a Remote Enhancer Position Requires a B-Cell-Restricted Activity

1992 • 63 citations

The cell-type-specific activator region of c-Jun juxtaposes constitutive and negatively regulated domains.

1992 • 54 citations

Reconstitution of transcriptional activation domains by reiteration of short peptide segments reveals the modular organization of a glutamine-rich activation domain.

1994 • 43 citations

Functional differences between the Oct2 transactivation domains determine the transactivation potential of individual Oct2 isoforms

1994 • 38 citations

Transcriptional activation by Oct-3: evidence for a specific role of the POU-specific domain in mediating functional interaction with Oct-1

1996 • 38 citations

Stringent integrity requirements for bothtrans-activation and DNA-binding in atrans-activator, Oct3

1991 • 38 citations

Both Oct-1 and Oct-2A contain domains which can activate the ubiquitously expressed U2 snRNA genes.

1991 • 31 citations

Cell-specific action and mutable structure of a transcription factor effector domain.

1993 • 31 citations

Transcriptional Activation and Repression, Two Properties of the Lymphoid‐Specific Transcription Factor Oct‐2a

1995 • 25 citations