Both Oct-1 and Oct-2A contain domains which can activate the ubiquitously expressed U2 snRNA genes.

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

1981 • 1,677 citations

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

1983 • 1,449 citations

A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype

1988 • 998 citations

Expression of a large family of POU-domain regulatory genes in mammalian brain development

1989 • 828 citations

Specific DNA binding of GAL4, a positive regulatory protein of yeast

1985 • 767 citations

The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products.

1988 • 750 citations

A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes

1986 • 740 citations

A new class of yeast transcriptional activators

1987 • 706 citations

Differential transcriptional activation by Oct-1 and Oct-2: Interdependent activation domains induce Oct-2 phosphorylation

1990 • 696 citations

The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.

1988 • 670 citations

Correct transcription of an immunoglobulin κ gene requires an upstream fragment containing conserved sequence elements

1984 • 669 citations

A family of octamer-specific proteins present during mouse embryogenesis: evidence for germline-specific expression of an Oct factor.

1989 • 664 citations

Structure of the 5' ends of immunoglobulin genes: a novel conserved sequence.

1984 • 564 citations

Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene

1987 • 516 citations

A cloned octamer transcription factor stimulates transcription from lymphoid–specific promoters in non–B cells

1988 • 494 citations

The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains.

1988 • 429 citations

An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity

1987 • 398 citations

Identification and purification of a human lymphoid-specific octamer-binding protein (OTF-2) that activates transcription of an immunoglobulin promoter in vitro

1987 • 386 citations

The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors

1988 • 334 citations

The POU domain is a bipartite DNA-binding structure

1988 • 304 citations

Interaction of cell-type-specific nuclear proteins with immunoglobulin VH promoter region sequences

1986 • 298 citations

Identification of a novel lymphoid specific octamer binding protein (OTF-2B) by proteolytic clipping bandshift assay (PCBA).

1988 • 284 citations

Nuclear factor III, a novel sequence-specific DNA-binding protein from HeLa cells stimulating adenovirus DNA replication

1986 • 256 citations

Cell type-specificity elements of the immunoglobulin heavy chain gene enhancer.

1987 • 255 citations

OVEC, a versatile system to study transcription in mammalian cells and cell-free extracts

1987 • 255 citations

An enhancer-like sequence within the Xenopus U2 gene promoter facilitates the formation of stable transcription complexes

1985 • 250 citations

Cooperative DNA binding of the yeast transcriptional activator GAL4.

1988 • 227 citations

Metal binding ‘finger’ structures in the glucocorticoid receptor defined by site-directed mutagenesis.

1988 • 199 citations

Repression of the IgH Enhancer in Teratocarcinoma Cells Associated with a Novel Octamer Factor

1989 • 176 citations

Activation of the U2 snRNA promoter by the octamer motif defines a new class of RNA polymerase II enhancer elements.

1988 • 174 citations

Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cells.

1990 • 146 citations

Octamer transcription factors bind to two different sequence motifs of the immunoglobulin heavy chain promoter.

1989 • 139 citations

The cell type-specific octamer transcription factor OTF-2 has two domains required for the activation of transcription.

1990 • 139 citations

Orientation-Dependent Transcriptional Activator Upstream of a Human U2 snRNA Gene

1985 • 132 citations

The Oct-2 protein binds cooperatively to adjacent octamer sites.

1989 • 132 citations

Functional cooperativity between protein molecules bound at two distinct sequence elements of the immunoglobulin heavy-chain promoter

1989 • 128 citations

How do different transcription factors binding the same DNA sequence sort out their jobs?

1989 • 126 citations

Cooperative interactions between transcription factors Sp1 and OTF-1.

1990 • 114 citations

Human U2 small nuclear RNA genes contain an upstream enhancer.

1986 • 112 citations

Distinct factors with Sp1 and NF-A specificities bind to adjacent functional elements of the human U2 snRNA gene enhancer.

1987 • 106 citations

Human U2 and U1 RNA genes use similar transcription signals.

1984 • 91 citations

Promoters with the octamer DNA motif (ATGCAAAT) can be ubiquitous or cell type-specific depending on binding affinity of the octamer site and Oct-factor concentration

1991 • 81 citations

Identification of proteins interacting with the enhancer of human U2 small nuclear RNA genes

1987 • 68 citations

Properties of a U1 RNA enhancer-like sequence

1987 • 47 citations

Synergistic activation of transcription by multiple binding sites for NF-κB even in absence of co-operative factor binding to DNA

1990 • 43 citations

The human U snRNA promoter and enhancer do not direct synthesis of messenger RNA

1988 • 40 citations

Nuclear factor I can functionally replace transcription factor Sp1 in a U2 small nuclear RNA gene enhancer

1989 • 26 citations