Regulation of Cadherin Adhesive Activity

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

Cell Adhesion: The Molecular Basis of Tissue Architecture and Morphogenesis

1996 • 3,454 citations

Cadherin Cell Adhesion Receptors as a Morphogenetic Regulator

1991 • 3,314 citations

From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion

1993 • 997 citations

Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene.

1993 • 912 citations

The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts

1997 • 772 citations

Alpha 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex.

1995 • 739 citations

Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor.

1994 • 712 citations

Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells.

1990 • 695 citations

Expressed recombinant cadherins mediate cell sorting in model systems

1988 • 673 citations

Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin.

1995 • 651 citations

Experimental specification of cell sorting, tissue spreading, and specific spatial patterning by quantitative differences in cadherin expression.

1994 • 580 citations

The Juxtamembrane Region of the Cadherin Cytoplasmic Tail Supports Lateral Clustering, Adhesive Strengthening, and Interaction with p120ctn

1998 • 566 citations

Regulation of Cell–Cell Adhesion by Rac and Rho Small G Proteins in MDCK Cells

1997 • 555 citations

Recycling of E-Cadherin

1999 • 538 citations

Nectin/PRR: An Immunoglobulin-like Cell Adhesion Molecule Recruited to Cadherin-based Adherens Junctions through Interaction with Afadin, a PDZ Domain–containing Protein

1999 • 527 citations

Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts.

1992 • 519 citations

Role of IQGAP1, a Target of the Small GTPases Cdc42 and Rac1, in Regulation of E-Cadherin- Mediated Cell-Cell Adhesion

1998 • 505 citations

The 102 kd cadherin-associated protein: Similarity to vinculin and posttranscriptional regulation of expression

1991 • 501 citations

Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors

1991 • 491 citations

Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes.

1994 • 490 citations

Selective Uncoupling of P120ctn from E-Cadherin Disrupts Strong Adhesion

2000 • 456 citations

Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts

1999 • 450 citations

Inhibition of Invasion of Epithelial Cells by Tiam1-Rac Signaling

1997 • 448 citations

Inside-out integrin signalling

1992 • 439 citations

Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia.

1996 • 422 citations

Tyrosine Phosphorylation of β-Catenin and Plakoglobin Enhanced by Hepatocyte Growth Factor and Epidermal Growth Factor in Human Carcinoma Cells

1994 • 421 citations

Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherin

1994 • 405 citations

armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of the polarized blastoderm epithelium in Drosophila.

1996 • 390 citations

Shroom, a PDZ Domain–Containing Actin-Binding Protein, Is Required for Neural Tube Morphogenesis in Mice

1999 • 366 citations

α-Catenin-Vinculin Interaction Functions to Organize the Apical Junctional Complex in Epithelial Cells

1998 • 338 citations

Structure-Function Analysis of Cell Adhesion by Neural (N-) Cadherin

1998 • 327 citations

Tyrosine phosphorylation and cadherin/catenin function

1997 • 318 citations

Quantitative analysis of cadherin-catenin-actin reorganization during development of cell-cell adhesion.

1996 • 316 citations

Receptor protein tyrosine phosphatase PTPmu associates with cadherins and catenins in vivo.

1995 • 313 citations

Lateral dimerization is required for the homophilic binding activity of C-cadherin.

1996 • 307 citations

Afadin

1999 • 282 citations

Discs Lost, a Novel Multi-PDZ Domain Protein, Establishes and Maintains Epithelial Polarity

1999 • 273 citations

Expression and distribution of cell adhesion molecule uvomorulin in mouse preimplantation embryos

1987 • 271 citations

Functional Domains of α-Catenin Required for the Strong State of Cadherin-based Cell Adhesion

1999 • 257 citations

Expression of Wnt-1 in PC12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion.

1993 • 249 citations

From Egg to Epithelium

1988 • 248 citations

p120ctn Acts as an Inhibitory Regulator of Cadherin Function in Colon Carcinoma Cells

1999 • 229 citations

Biosynthesis of the cell adhesion molecule uvomorulin (E-cadherin) in Madin-Darby canine kidney epithelial cells.

1991 • 226 citations

Cdc42 and Rac1 Regulate the Interaction of IQGAP1 with β-Catenin

1999 • 223 citations

Catenin-dependent and -independent Functions of Vascular Endothelial Cadherin

1995 • 220 citations

V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta catenin is not required for the shift.

1995 • 216 citations

Purification of a 92-kDa cytoplasmic protein tightly associated with the cell-cell adhesion molecule E-cadherin (uvomorulin)

1991 • 208 citations

Altered Cell Adhesion Activity by Pervanadate Due to the Dissociation of α-Catenin from the E-Cadherin·Catenin Complex

1998 • 206 citations

Regulation of cadherin-mediated cell–cell adhesion by the Rho family GTPases

1999 • 204 citations

CDC42 and Rac1 control different actin-dependent processes in the Drosophila wing disc epithelium.

1995 • 190 citations

Region-Specific Cell Activities in Amphibian Gastrulation

1986 • 180 citations

The Drosophila genes crumbs and stardust are involved in the biogenesis of adherens junctions

1996 • 176 citations

The Membrane-proximal Region of the E-Cadherin Cytoplasmic Domain Prevents Dimerization and Negatively Regulates Adhesion Activity

1998 • 173 citations

δ-catenin, an Adhesive Junction–associated Protein Which Promotes Cell Scattering

1999 • 172 citations

p120ctn Binds to the Membrane-proximal Region of the E-cadherin Cytoplasmic Domain and Is Involved in Modulation of Adhesion Activity

1999 • 171 citations

Regulation of C-cadherin function during activin induced morphogenesis of Xenopus animal caps.

1994 • 156 citations

β-Catenin Has Wnt-like Activity and Mimics the Nieuwkoop Signaling Center inXenopusDorsal–Ventral Patterning

1995 • 142 citations

Analysis of C-cadherin Regulation during Tissue Morphogenesis with an Activating Antibody

1999 • 104 citations

Posttranslational regulation of plakoglobin expression. Influence of the desmosomal cadherins on plakoglobin metabolic stability.

1994 • 102 citations

Identification of a New Catenin: the Tyrosine Kinase Substrate p120^cas Associates with E-Cadherin Complexes

1994 • 102 citations