Localization of the Adhesion Receptor Glycoprotein Ib-IX-V Complex to Lipid Rafts Is Required for Platelet Adhesion and Activation

Regulation of Renal Organic Anion Transporter 3 (SLC22A8) Expression and Function by the Integrity of Lipid Raft Domains and their Associated Cytoskeleton

2013 • 2,950 citations

Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

1992 • 2,905 citations

Structure and Function of Sphingolipid- and Cholesterol-rich Membrane Rafts

2000 • 2,321 citations

How Cells Handle Cholesterol

2000 • 1,230 citations

Lipid Domain Structure of the Plasma Membrane Revealed by Patching of Membrane Components

1998 • 1,193 citations

Platelets and shear stress

1996 • 871 citations

Cellular Cholesterol Efflux Mediated by Cyclodextrins

1995 • 864 citations

LAT Palmitoylation

1998 • 837 citations

Aggregation of Lipid Rafts Accompanies Signaling via the T Cell Antigen Receptor

1999 • 800 citations

P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin.

1995 • 712 citations

Role of Lipid Modifications in Targeting Proteins to Detergent-resistant Membrane Rafts

1999 • 626 citations

Emerging Themes in Lipid Rafts and Caveolae

2001 • 567 citations

A Role for Lipid Rafts in B Cell Antigen Receptor Signaling and Antigen Targeting

1999 • 473 citations

Platelet hypersensitivity induced by cholesterol incorporation.

1975 • 464 citations

The role of lipid rafts in T cell antigen receptor (TCR) signalling

2000 • 453 citations

Inhibition of Protein Palmitoylation, Raft Localization, and T Cell Signaling by 2-Bromopalmitate and Polyunsaturated Fatty Acids

2000 • 452 citations

Cysteine3 of Src family protein tyrosine kinase determines palmitoylation and localization in caveolae.

1994 • 389 citations

A central role for microvillous receptor presentation in leukocyte adhesion under flow

1995 • 380 citations

von Willebrand factor binding to platelet GpIb initiates signals for platelet activation.

1991 • 280 citations

The Platelet Glycoprotein Ib-IX-V Complex

2017 • 269 citations

The platelet glycoprotein Ib???IX complex

1994 • 259 citations

Purification and preliminary characterization of the glycoprotein Ib complex in the human platelet membrane

1985 • 229 citations

Compartmentalized IgE Receptor–mediated Signal Transduction in Living Cells

1997 • 189 citations

Transmembrane Calcium Influx Associated with von Willebrand Factor Binding to GP Ib in the Initiation of Shear-Induced Platelet Aggregation

1993 • 171 citations

Glycoprotein Ib-V-IX, a Receptor for von Willebrand Factor, Couples Physically and Functionally to the Fc Receptor γ-Chain, Fyn, and Lyn to Activate Human Platelets

1999 • 159 citations

Physical Proximity and Functional Interplay of the Glycoprotein Ib-IX-V Complex and the Fc Receptor FcγRIIA on the Platelet Plasma Membrane

1998 • 149 citations

Evidence for a physiological role for membrane rafts in human platelets

2001 • 142 citations

Membrane organization in immunoglobulin E receptor signaling

1999 • 135 citations

Adhesion receptor activation of phosphatidylinositol 3-kinase. von Willebrand factor stimulates the cytoskeletal association and activation of phosphatidylinositol 3-kinase and pp60c-src in human platelets.

1994 • 133 citations

Biochemical isolation of a membrane microdomain from resting platelets highly enriched in the plasma membrane glycoprotein CD36

1996 • 130 citations

Cross-linking of a monomeric 39/34-kDa dispase fragment of von Willebrand factor (Leu-480/Val-481-Gly-718) to the N-terminal region of the .alpha.-chain of membrane glycoprotein Ib on intact platelets with bis(sulfosuccinimidyl) suberate

1989 • 122 citations

Leukocyte activation induces surface redistribution of P-selectin glycoprotein ligand-1

1997 • 115 citations

Synergistic Adhesive Interactions and Signaling Mechanisms Operating between Platelet Glycoprotein Ib/IX and Integrin αIIbβ3

2000 • 106 citations

Dual Fatty Acylation of p59Fyn Is Required for Association with the T Cell Receptor ζ Chain through Phosphotyrosine–Src Homology Domain-2 Interactions

1999 • 105 citations

Mapping the Glycoprotein Ib-binding Site in the von Willebrand Factor A1 Domain

2000 • 103 citations

Lipid Rafts Orchestrate Signaling by the Platelet Receptor Glycoprotein VI

2002 • 102 citations

Differential role of glycolipid-enriched membrane domains in glycoprotein VI- and integrin-mediated phospholipase Cγ2 regulation in platelets

2002 • 99 citations

Palmitoylation of Either Cys-3 or Cys-5 Is Required for the Biological Activity of the Lck Tyrosine Protein Kinase

1995 • 98 citations

Production of Phosphatidylinositol 3,4,5-Trisphosphate and Phosphatidic Acid in Platelet Rafts: Evidence for a Critical Role of Cholesterol-Enriched Domains in Human Platelet Activation

2001 • 87 citations

Signaling across the Platelet Adhesion Receptor Glycoprotein Ib-IX Induces αIIbβ3 Activation Both in Platelets and a Transfected Chinese Hamster Ovary Cell System

2000 • 85 citations

Glycoprotein Ib-von Willebrand Factor Interactions Activate Tyrosine Kinases in Human Platelets

1997 • 85 citations

Platelets; a practical approach

1998 • 82 citations

Cell calcium signaling via GM1 cell surface gangliosides in the human Jurkat T cell line.

1994 • 79 citations

Shear-stress-induced von Willebrand factor binding to platelets causes the activation of tyrosine kinase(s)

1994 • 77 citations

Binding of a Novel 50-kilodalton Alboaggregin from Trimeresurus albolabris and Related Viper Venom Proteins to the Platelet Membrane Glycoprotein Ib-IX-V Complex. Effect on Platelet Aggregation and Glycoprotein Ib-Mediated Platelet Activation

1996 • 76 citations

Platelet Activation by von Willebrand Factor Requires Coordinated Signaling through Thromboxane A2 and FcγIIA Receptor

2001 • 74 citations

Interaction of porcine von Willebrand factor with the platelet glycoproteins Ib and IIb/IIIa complex

1992 • 74 citations

Activation of Human Platelets by the Membrane-Expressed A1 Domain of von Willebrand Factor

1997 • 72 citations

Glycoprotein Ib-von Willebrand Factor Interactions Activate Tyrosine Kinases in Human Platelets

1997 • 68 citations

Porcine von Willebrand Factor Binding to Human Platelet GPIb Induces Transmembrane Calcium Influx

1996 • 66 citations

Echicetin, a GPIb-binding snake C-type lectin from Echis carinatus, also contains a binding site for IgMκ responsible for platelet agglutination in plasma and inducing signal transduction

2001 • 60 citations

Rap1B and Rap2B Translocation to the Cytoskeleton by von Willebrand Factor Involves FcγII Receptor-mediated Protein Tyrosine Phosphorylation

1999 • 57 citations

Alboaggregins A and B. Structure and Interaction with Human Platelets

1998 • 57 citations

Constitutive and functional association of the platelet collagen receptor glycoprotein VI–Fc receptor γ-chain complex with membrane rafts

2002 • 54 citations

Glycoprotein Ib and glycoprotein IX in human platelets are acylated with palmitic acid through thioester linkages

1989 • 48 citations

Adhesive properties of the isolated amino-terminal domain of platelet glycoprotein Ibα in a flow field

1999 • 42 citations

Plasma Lipids and Platelet Membrane Fluidity in Essential Hypertension

1993 • 36 citations

Interaction between GPIbα and FcγIIA Receptor in Human Platelets

1999 • 25 citations

Perfusion studies on the formation of mural thrombi with cholesterol-modified and hypercholesterolemic platelets.

1985 • 20 citations

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