Membrane organization in immunoglobulin E receptor signaling

Functional rafts in cell membranes

1997 • 9,471 citations

The Fluid Mosaic Model of the Structure of Cell Membranes

1972 • 8,835 citations

FUNCTIONS OF LIPID RAFTS IN BIOLOGICAL MEMBRANES

1998 • 2,942 citations

THE CAVEOLAE MEMBRANE SYSTEM

1998 • 1,947 citations

SINGLE-PARTICLE TRACKING:Applications to Membrane Dynamics

1997 • 1,768 citations

GPI-anchored proteins are organized in submicron domains at the cell surface

1998 • 1,207 citations

Structure and Origin of Ordered Lipid Domains in Biological Membranes

1998 • 962 citations

Membrane Compartmentation Is Required for Efficient T Cell Activation

1998 • 925 citations

Interactions between saturated acyl chains confer detergent resistance on lipids and glycosylphosphatidylinositol (GPI)-anchored proteins: GPI-anchored proteins in liposomes and cells show similar behavior.

1994 • 688 citations

On the Origin of Sphingolipid/Cholesterol-Rich Detergent-Insoluble Cell Membranes: Physiological Concentrations of Cholesterol and Sphingolipid Induce Formation of a Detergent-Insoluble, Liquid-Ordered Lipid Phase in Model Membranes

1997 • 661 citations

Hydrophobic mismatch between proteins and lipids in membranes

1998 • 605 citations

Sphingolipid organization in biomembranes: what physical studies of model membranes reveal

1998 • 484 citations

Distribution of a Glycosylphosphatidylinositol-anchored Protein at the Apical Surface of MDCK Cells Examined at a Resolution of <100 Å Using Imaging Fluorescence Resonance Energy Transfer

1998 • 452 citations

Cholesterol and Sphingolipid Enhance the Triton X-100 Insolubility of Glycosylphosphatidylinositol-anchored Proteins by Promoting the Formation of Detergent-insoluble Ordered Membrane Domains

1998 • 415 citations

Cell surface organization by the membrane skeleton

1996 • 378 citations

Compartmentalized Activation of the High Affinity Immunoglobulin E Receptor within Membrane Domains

1997 • 353 citations

Fluorescence correlation spectroscopy: Diagnostics for sparse molecules

1997 • 316 citations

Transient Confinement of a Glycosylphosphatidylinositol-Anchored Protein in the Plasma Membrane

1997 • 303 citations

Fc epsilon RI-mediated recruitment of p53/56lyn to detergent-resistant membrane domains accompanies cellular signaling.

1995 • 290 citations

Transfection of Syk protein tyrosine kinase reconstitutes high affinity IgE receptor-mediated degranulation in a Syk-negative variant of rat basophilic leukemia RBL-2H3 cells.

1996 • 265 citations

Lipid microdomains in cell surface membranes

1997 • 245 citations

Transphosphorylation as the mechanism by which the high-affinity receptor for IgE is phosphorylated upon aggregation.

1994 • 194 citations

Compartmentalized IgE Receptor–mediated Signal Transduction in Living Cells

1997 • 189 citations

Domains in Cell Plasma Membranes Investigated by Near-Field Scanning Optical Microscopy

1998 • 183 citations

Large-scale co-aggregation of fluorescent lipid probes with cell surface proteins.

1994 • 146 citations

The Unique Domain as the Site on Lyn Kinase for Its Constitutive Association with the High Affinity Receptor for IgE

1997 • 124 citations

Antigen-Mediated IGE Receptor Aggregation and Signaling: A Window on Cell Surface Structure and Dynamics

1996 • 120 citations

Structural Aspects of the Association of FcεRI with Detergent-resistant Membranes

1999 • 105 citations

Downstream signals initiated in mast cells by FcεRI and other receptors

1996 • 94 citations

Fc epsilon RI-mediated association of 6-micron beads with RBL-2H3 mast cells results in exclusion of signaling proteins from the forming phagosome and abrogation of normal downstream signaling.

1996 • 77 citations

New insights into membrane dynamics from the analysis of cell surface interactions by physical methods

1995 • 67 citations

Chapter 8 Lateral Diffusion of Lipids and Proteins

1999 • 55 citations

Image cross-correlation spectroscopy: A new experimental biophysical approach to measurement of slow diffusion of fluorescent molecules

1996 • 53 citations

Signal transduction through the conserved motifs of the high affinity IgE receptor FcεRI

1995 • 52 citations

A Carbon-13 Nuclear Magnetic Resonance Spectroscopic Study of Inter-Proton Pair Order Parameters: A New Approach to StudyOrder and Dynamics in Phospholipid Membrane Systems

1998 • 51 citations

Mono- and bilayers of phospholipids at interfaces: interlayer coupling and phase stability

1985 • 44 citations

Visualization of domain formation in the inner and outer leaflets of a phospholipid bilayer.

1988 • 43 citations

Lateral diffusion of specific antibodies bound to lipid monolayers on alkylated substrates.

1986 • 41 citations

Lipid-gramicidin interactions using two-dimensional Fourier-transform electron spin resonance

1997 • 34 citations

Partitioning of Proteins into Plasma Membrane Microdomains

1997 • 32 citations

Alteration of Lipid Composition Modulates Fc.epsilon.RI Signaling in RBL-2H3 Cells

1995 • 21 citations