Purification and preliminary characterization of the glycoprotein Ib complex in the human platelet membrane

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Continuous cultures of fused cells secreting antibody of predefined specificity

1975 • 17,037 citations

Immunochemical quantitation of antigens by single radial immunodiffusion

1965 • 9,369 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

Silver staining of proteins in polyacrylamide gels

1981 • 3,565 citations

A Method of Trace Iodination of Proteins for Immunologic Studies

1966 • 2,148 citations

Glycoprotein staining following electrophoresis on acrylamide gels

1969 • 1,947 citations

Production of monoclonal antibodies: Strategy and tactics

1980 • 1,594 citations

Platelets in Biology and Pathology

1981 • 644 citations

Human erythrocyte membrane glycoprotein: A re-evaluation of the molecular weight as determined by SDS polyacrylamide gel electrophoresis

1971 • 552 citations

N-hydroxysulfosuccinimide active esters: bis(N-hydroxysulfosuccinimide) esters of two dicarboxylic acids are hydrophilic, membrane-impermeant, protein cross-linkers

1982 • 481 citations

Immunochemical quantitation of antigens by single radial immunodiffusion

1965 • 475 citations

Studies with a murine monoclonal antibody that abolishes ristocetin- induced binding of von Willebrand factor to platelets: additional evidence in support of GPIb as a platelet receptor for von Willebrand factor

1983 • 469 citations

Platelet plasma membrane glycoproteins. Evidence for the presence of nonequivalent disulfide bonds using nonreduced-reduced two-dimensional gel electrophoresis.

1977 • 451 citations

Isolation and Characterization of Plasma Membranes from Human Blood Platelets

1970 • 429 citations

Identification of membrane proteins mediating the interaction of human platelets

1980 • 383 citations

Identification and partial purification of ankyrin, the high affinity membrane attachment site for human erythrocyte spectrin

1979 • 355 citations

Progress in Hemostasis and Thrombosis.

1974 • 349 citations

Purification of glycoproteins IIb and III from human platelet plasma membranes and characterization of a calcium-dependent glycoprotein IIb-III complex.

1982 • 337 citations

Interaction of AP-2, a monoclonal antibody specific for the human platelet glycoprotein IIb-IIIa complex, with intact platelets.

1983 • 315 citations

Ca2+-dependent protease in human platelets. Specific cleavage of platelet polypeptides in the presence of added Ca2+.

1977 • 274 citations

Effect of trypsin on the exposed polypeptides and glycoproteins in the human platelet membrane

1972 • 269 citations

Decreased adhesion of giant (Bernard-Soulier) platelets to subendothelium

1974 • 265 citations

The formation of Ca++-dependent complexes of platelet membrane glycoproteins IIb and IIIa in solution as determined by crossed immunoelectrophoresis

1981 • 261 citations

Characterization of the platelet membrane glycoprotein abnormalities in Bernard-Soulier syndrome and comparison with normal by surface-labeling techniques and high-resolution two-dimensional gel electrophoresis.

1982 • 245 citations

Identification of two proteins (actin-binding protein and P235) that are hydrolyzed by endogenous Ca2+-dependent protease during platelet aggregation.

1985 • 236 citations

Isolation and Quantitation of the Platelet Membrane Glycoprotein Deficient in Thrombasthenia Using a Monoclonal Hybridoma Antibody

1980 • 209 citations

Platelet glycocalicin. Interaction with thrombin and role as thrombin receptor of the platelet surface.

1978 • 209 citations

Additional glycoprotein defects in Bernard-Soulier's syndrome: confirmation of genetic basis by parental analysis

1983 • 186 citations

Immunochemical Evidence for Protein Abnormalities in Platelets from Patients with Glanzmann's Thrombasthenia and Bernard-Soulier Syndrome

1980 • 176 citations

Monoclonal Antibody to Human Platelet Glycoprotein I I. IMMUNOLOGICAL STUDIES

1981 • 166 citations

Platelet glycocalicin. II. Purification and characterization.

1976 • 145 citations

Purification and preliminary physicochemical characterization of human platelet membrane glycoprotein V.

1981 • 137 citations

Isolation of the membrane glycoproteins of human blood platelets by lectin affinity chromatography

1977 • 133 citations

Monoclonal Antibody to Human Platelet Glycoprotein I II. EFFECTS ON HUMAN PLATELET FUNCTION

1981 • 127 citations

Monoclonal Antibodies against Platelet Membrane Glycoproteins. Characterization and Effect on Platelet Function

1983 • 118 citations

Specific protein and glycoprotein deficiencies in platelets isolated from two patients with the gray platelet syndrome

1982 • 116 citations

Platelet glycocalicin: A single receptor for platelet aggregation induced by thrombin or ristocetin

1976 • 116 citations

Platelet glycocalicin. Its membrane association and solubilization in aqueous media

1980 • 103 citations

Purification of human platelet calcium-activated protease. Effect on platelet and endothelial function.

1983 • 95 citations

Characterization of Human Platelet Proteins Solubilized with Triton X‐100 and Examined by Crossed Immunoelectrophoresis

1979 • 90 citations

Relationship between glycocalicin and glycoprotein Ib of human platelets.

1981 • 90 citations

Absence of the platelet receptor for drug-dependent antibodies in the Bernard-Soulier syndrome.

1978 • 89 citations

Further studies of the human platelet receptor for quinine- and quinine-dependent antibodies.

1981 • 86 citations

ROLE OF VON WILLEBRAND FACTOR IN PLATELET ADHESION TO THE SUBENDOTHELIUM

1983 • 86 citations

Genetic polymorphism of platelet glycoprotein Ib

1984 • 85 citations

The carbohydrate moiety of human platelet glycocalicin.

1983 • 85 citations

Characterization of human platelet glycoprotein antigens giving rise to individual immunoprecipitates in crossed-immunoelectrophoresis

1981 • 71 citations

Quinidine-induced thrombocytopenia and leukopenia: demonstration and characterization of distinct antiplatelet and antileukocyte antibodies

1983 • 69 citations

Isolation and structural characterization of the polypeptide subunits of membrane glycoprotein IIb-IIIa from human platelets

1982 • 68 citations

Platelet membrane glycoproteins: Alteration during storage of human platelet concentrates

1976 • 67 citations

Inhibition of Renal Metabolism. Relative effects of arsenate on sodium, phosphate, and glucose transport by the rabbit proximal tubule.

1980 • 64 citations

Interaction of blood platelets with a microfibrillar extract from adult bovine aorta: requirement for von Willebrand factor.

1983 • 62 citations

ROLE OF VON WILLEBRAND FACTOR IN PLATELET ADHESION TO THE SUBENDOTHELIUM

1983 • 59 citations

Demonstration of a new glycoprotein Ib-related component in platelet extracts prepared in the presence of leupeptin

1983 • 58 citations

Isolation and characterization of the major oligosaccharide of human platelet membrane glycoprotein GPIb

1982 • 50 citations

Glycoprotein Ib in the triton-insoluble (cytoskeletal) fraction of blood platelets

1984 • 49 citations

Crossed immunoelectrophoresis of human platelet membranes. Diminished major antigen in Glanzmann's thrombasthenia and Bernard-Soulier syndrome.

1980 • 44 citations

Wheat germ agglutinin affinity chromatography of human platelet membrane glycoproteins

1978 • 39 citations

Human platelet glycoproteins. Further evidence that the “GP I Band” from whole platelets contains three different polypeptides one of which may be involved in the interaction between platelets and factor VIII

1977 • 37 citations

Monoclonal antibodies against antigens of the human platelet surface: preparation and properties

1984 • 36 citations

Structural analysis of human platelet membrane glycoprotein I complex.

1979 • 36 citations

Factor VIII/von Willebrand Factor has potent lectin activity

1984 • 30 citations

Characterization of calcium-dependent binding of endogenous factor VIII/von Willebrand factor to surface activated platelets

1984 • 22 citations

Isolation of platelet glycocalicin by affinity chromatography on thrombin-sepharose

1982 • 18 citations

Identification of membrane proteins of human blood platelets with a hydrophobic photolabel

1984 • 3 citations

Evidence that the Monoclonal Antibody an 51 is Directed Against Platelet Membrane Glycoprotein IB

1983 • 2 citations