Immune cells, pancreas development, regeneration and type 1 diabetes

Inflammation: the link between insulin resistance, obesity and diabetes

2003 • 2,083 citations

Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo

2002 • 1,445 citations

The Nonobese Diabetic Mouse as a Model of Autoimmune Diabetes: Immune Dysregulation Gets the NOD

1997 • 685 citations

Dynamics of β-cell Mass in the Growing Rat Pancreas: Estimation With a Simple Mathematical Model

1995 • 607 citations

Pancreatic organogenesis — developmental mechanisms and implications for therapy

2002 • 506 citations

The Murine Autoimmune Diabetes Model: NOD and Related Strains

1992 • 498 citations

Handbook of Physiology Section 7: Endocrinology

1976 • 448 citations

Postnatal mammary gland development requires macrophages and eosinophils

2000 • 429 citations

Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences

2001 • 427 citations

The mononuclear phagocyte system revisited

2002 • 415 citations

The inflammatory macrophage: a story of Jekyll and Hyde

2002 • 406 citations

Intercellular signals regulating pancreas development and function

2001 • 399 citations

Apoptosis Participates in the Remodeling of the Endocrine Pancreas in the Neonatal Rat*

1997 • 399 citations

Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences

2001 • 394 citations

Islet growth and development in the adult

2000 • 338 citations

The extracellular matrix can regulate vascular cell migration, proliferation, and survival: relationships to vascular disease

2000 • 331 citations

Immunohistochemical Characterization of Monocytes-Macrophages and Dendritic Cells Involved in the Initiation of the Insulitis and β-Cell Destruction in NOD Mice

1994 • 331 citations

Epithelial cell proliferation and islet neogenesis in IFN-g transgenic mice

1993 • 325 citations

Apoptosis: definition, mechanisms, and relevance to disease

1999 • 324 citations

The Role of Macrophages in T Cell–mediated Autoimmune Diabetes in Nonobese Diabetic Mice

1999 • 279 citations

The Pathophysiology of Angiogenesis

1995 • 269 citations

Role of endothelial cells in early pancreas and liver development

2002 • 257 citations

Signal transduction during Fc receptor-mediated phagocytosis

2002 • 242 citations

The inflammatory macrophage: a story of Jekyll and Hyde

2003 • 241 citations

Signaling and transcriptional control of pancreatic organogenesis

2002 • 239 citations

Regulation of beta-cell mass by hormones and growth factors.

2001 • 236 citations

OLETF (Otsuka Long-Evans Tokushima Fatty) rat: a new NIDDM rat strain

1994 • 235 citations

Differentiation of New Insulin-Producing Cells Is Induced by Injury in Adult Pancreatic Islets¹

1997 • 231 citations

Autoimmune-prone mice share a promoter haplotype associated with reduced expression and function of the Fc receptor FcγRII

2000 • 214 citations

Autoimmune islet destruction in spontaneous type 1 diabetes is not β-cell exclusive

2003 • 200 citations

Lymphoepithelial Cysts of the Pancreas: a Report of 12 Cases and a Review of the Literature

2002 • 193 citations

Role of leukocytes and endothelial cells in the development of angiogenesis in inflammation and wound healing.

2001 • 185 citations

Role of Leukocytes and Endothelial Cells in the Development of Angiogenesis in Inflammation and Wound Healing

2001 • 171 citations

Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model

1995 • 162 citations

β-Cell Neogenesis During Prolonged Hyperglycemia in Rats

2002 • 160 citations

Phagocytosis of Apoptotic Cells by Macrophages From NOD Mice Is Reduced

2002 • 153 citations

Expression of a tumor necrosis factor alpha transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes.

1992 • 151 citations

Dendritic cells derived from peripheral monocytes express endothelial markers and in the presence of angiogenic growth factors differentiate into endothelial-like cells

2001 • 137 citations

Apoptosis Participates in the Remodeling of the Endocrine Pancreas in the Neonatal Rat

1997 • 120 citations

Beta cell MHC class I is a late requirement for diabetes

2003 • 114 citations

Spontaneous development of organ-specific autoimmune lesions in aged C57BL/6 mice.

1989 • 95 citations

Immunohistochemical characterization of monocytes-macrophages and dendritic cells involved in the initiation of the insulitis and beta-cell destruction in NOD mice

1994 • 84 citations

Differentiation of New Insulin-Producing Cells Is Induced by Injury in Adult Pancreatic Islets

1997 • 77 citations

α-Cell Neogenesis in an Animal Model of IDDM

1997 • 66 citations

Animal models of endocrine/organ-specific autoimmune diseases: do they really help us to understand human autoimmunity?

2002 • 65 citations

An Immunohistochemical Study on Organized Lymphoid Cell Infiltrates in Fetal and Neonatal Pancreases: A comparison with similar infiltrates found in the pancreas of a diabetic infant

1993 • 59 citations

Abnormalities in dendritic cell and macrophage accumulation in the pancreas of nonobese diabetic (NOD) mice during the early neonatal period.

2002 • 53 citations

Modulation of Leukocyte Behavior by an Inflamed Extracellular Matrix

2000 • 47 citations

Cell adhesion molecules and extracellular-matrix constituents in kidney development and disease

1999 • 46 citations

Islet abnormalities in the pathogenesis of autoimmune diabetes

2002 • 44 citations

Is innervation an early target in autoimmune diabetes?

2003 • 40 citations

Expression pattern of macrophage migration inhibitory factor during embryogenesis

1999 • 35 citations

In situ kinetics of acinar, duct, and inflammatory cells in duct ligation-lnduced pancreatitis in rats

1993 • 32 citations

Peripheral T‐cell tolerance: the contribution of permissive T‐cell migration into parenchymal tissues of the neonate

1999 • 31 citations

Spontaneous autoimmune reactions against pancreatic islets in mouse strains with generalized autoimmune disease

1980 • 31 citations

Presence of Pancreatic Hormones in Islet Cells With MHC-Class II Antigen Expression

1987 • 30 citations

The Diabetes-Prone NZO/Hl Strain. II. Pancreatic Immunopathology

2002 • 30 citations

alpha-Cell neogenesis in an animal model of IDDM

1997 • 23 citations

Proapoptosis and Antiapoptosis-Related Molecules During Postnatal Pancreas Development in Control and Nonobese Diabetic Mice: Relationship with Innervation

2003 • 20 citations

Ontogeny of Extracellular Matrix Gene Expression by Rat Lung Cells at Late Fetal Gestation

1998 • 19 citations

Ductal lesions of exocrine glands and insulitis induced by L3T4+ T cells following graft-versus-host reaction due to major histocompatibility complex class II disparity

1990 • 16 citations

Extracellular signals and pancreatic beta-cell development: a brief review.

2002 • 15 citations

New insights into insulin dependent diabetes mellitus from studies with transgenic mouse models.

1997 • 15 citations

Extracellular Signals and Pancreatic β-cell Development: A Brief Review

2002 • 15 citations

NOD Fetal Thymus Organ Culture: Anin VitroModel for the Development of T Cells Involved in IDDM

1997 • 15 citations

Regeneration of Beta-cells in Response to Islet Inflammation

2009 • 14 citations

Peripheral Insulin Insensitivity in the Hyperglycemic Athymic Nude Mouse: Similarity to Noninsulin-Dependent Diabetes Mellitus

1991 • 12 citations

Presence of pancreatic hormones in islet cells with MHC-class II antigen expression

1987 • 11 citations

Novel Islet, Duct, and Acinar Cell Markers Defined by Monoclonal Autoantibodies from Prediabetic BB Rats

1990 • 10 citations

Anti-Endothelial Cell Autoantibodies in BB Rats With Spontaneous and Induced IDDM

1996 • 9 citations

Monocyte/macrophage initiation of organ-specific autoimmunity: the ultimate ‘bystander’ hypothesis?

2002 • 9 citations

Pancreatic expression of antigens for islet cell antibodies in non-obese diabetic mice

1995 • 8 citations

The immunology of the human foetal pancreas aged 8–13 gestational weeks

1991 • 6 citations

Anti-endothelial cell autoantibodies in BB rats with spontaneous and induced IDDM

1996 • 6 citations

The immunology of the human foetal pancreas aged 8?13 gestational weeks

1991 • 5 citations

Immunohistochemical and electron microscope studies of rat islets of Langerhans one month after adult thymectomy.

1992 • 4 citations

Islet cell cytoplasmic antibody reactivity in midgestational human fetal pancreas

1994 • 1 citations