Proapoptosis and Antiapoptosis-Related Molecules During Postnatal Pancreas Development in Control and Nonobese Diabetic Mice: Relationship with Innervation

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

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Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice

1993 • 962 citations

Insulin-Dependent Diabetes Mellitus as an Autoimmune Disease

1994 • 818 citations

Dynamics of β-cell Mass in the Growing Rat Pancreas: Estimation With a Simple Mathematical Model

1995 • 607 citations

Autoimmune disease: why and where it occurs

2001 • 584 citations

Systemic Exposure to Irradiated Apoptotic Cells Induces Autoantibody Production

1998 • 573 citations

Mechanisms and Physiological Significance of the Cholinergic Control of Pancreatic β-Cell Function

2001 • 480 citations

The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity

2000 • 440 citations

CD95 Ligand (Fas-L/APO-1L) and Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Mediate Ischemia-Induced Apoptosis in Neurons

1999 • 435 citations

Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences

2001 • 427 citations

Apoptosis Participates in the Remodeling of the Endocrine Pancreas in the Neonatal Rat*

1997 • 399 citations

Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences

2001 • 394 citations

Recognizing death: the phagocytosis of apoptotic cells

1998 • 381 citations

Macrophages are required for cell death and tissue remodeling in the developing mouse eye

1993 • 355 citations

Markers of mouse macrophage development detected by monoclonal antibodies

1994 • 345 citations

Immunohistochemical Characterization of Monocytes-Macrophages and Dendritic Cells Involved in the Initiation of the Insulitis and β-Cell Destruction in NOD Mice

1994 • 331 citations

β cell apoptosis in T cell-mediated autoimmune diabetes

1997 • 330 citations

Apoptosis: definition, mechanisms, and relevance to disease

1999 • 324 citations

Chemokine and chemokine receptor expression in the central nervous system

1999 • 293 citations

Neonatal beta-cell apoptosis: a trigger for autoimmune diabetes?

2000 • 292 citations

The Role of Macrophages in Wallerian Degeneration

1997 • 276 citations

The nonobese diabetic scid mouse: model for spontaneous thymomagenesis associated with immunodeficiency.

1992 • 274 citations

Programmed Cell Death in the Developing Nervous System

1996 • 263 citations

The role of FasL-induced apoptosis in immune privilege

1997 • 262 citations

bcl-2 transgene expression can protect neurons against developmental and induced cell death.

1995 • 261 citations

Defects in the differentiation and function of antigen presenting cells in NOD/Lt mice.

1993 • 254 citations

Programmed Cell Death of Embryonic Motoneurons Triggered through the FAS Death Receptor

1999 • 240 citations

FasL (CD95L, Apo1L) is expressed in the normal rat and human brain: Evidence for the existence of an immunological brain barrier

1999 • 222 citations

Apoptosis: molecular aspects of cell death and disease.

1998 • 217 citations

Apoptosis in the Pancreatic Islet Cells of the Neonatal Rat Is Associated with a Reduced Expression of Insulin-Like Growth Factor II that May Act as a Survival Factor*

1998 • 210 citations

Apoptosis Is the Mode of β-Cell Death Responsible for the Development of IDDM in the Nonobese Diabetic (NOD) Mouse

1997 • 203 citations

Death the Fas way: regulation and pathophysiology of CD95 and its ligand

2000 • 201 citations

Elimination of maternally transmitted autoantibodies prevents diabetes in nonobese diabetic mice

2002 • 195 citations

Role of BCL-2 in the survival and function of developing and mature sympathetic neurons

1995 • 193 citations

Dendritic cells and macrophages are the first and major producers of TNF-alpha in pancreatic islets in the nonobese diabetic mouse.

1998 • 182 citations

First appearance, distribution, and origin of macrophages in the early development of the avian central nervous system

1993 • 181 citations

Cell Death Mediators in Autoimmune Diabetes—No Shortage of Suspects

1997 • 177 citations

Structural and Functional Considerations of GABA in Islets of Langerhans: β-Cells and Nerves

1991 • 157 citations

Immunohistochemical Analysis of Bcl-2, Bax, Bcl-X, and Mcl-1 Expression in Pancreatic Cancers

1999 • 156 citations

Phagocytosis of Apoptotic Cells by Macrophages From NOD Mice Is Reduced

2002 • 153 citations

Tolerance to Islet Antigens and Prevention from Diabetes Induced by Limited Apoptosis of Pancreatic β Cells

2002 • 151 citations

Dendritic Cells and Macrophages Are the First and Major Producers of TNF-α in Pancreatic Islets in the Nonobese Diabetic Mouse

1998 • 146 citations

Chemokines and their receptors in neurobiology: perspectives in physiology and homeostasis

2000 • 129 citations

Evidence that beta cell death in the nonobese diabetic mouse is Fas independent.

1999 • 114 citations

Prolonged Expression of Interferon‐Inducible Protein‐10 in Ischemic Cortex After Permanent Occlusion of the Middle Cerebral Artery in Rat

1998 • 108 citations

Islet morphogenesis and stem cell markers in rat pancreas.

1996 • 104 citations

Macrophages and nerve regeneration

1992 • 97 citations

Clearing the way to mechanisms of autoimmunity

2001 • 91 citations

Evidence That β Cell Death in the Nonobese Diabetic Mouse Is Fas Independent

1999 • 89 citations

Defective Fc gamma RII gene expression in macrophages of NOD mice: genetic linkage with up-regulation of IgG1 and IgG2b in serum.

1996 • 86 citations

Type I Diabetes and Multiple Sclerosis Patients Target Islet Plus Central Nervous System Autoantigens; Nonimmunized Nonobese Diabetic Mice Can Develop Autoimmune Encephalitis

2001 • 85 citations

Apoptosis: Programmed cell death in fetal development

1996 • 85 citations

Splenic Macrophages From the NOD Mouse Are Defective in the Ability to Present Antigen

1998 • 84 citations

Expression of Fas Antigen in the Normal Mouse Brain

1998 • 81 citations

Sequential expression of chemokines in experimental autoimmune neuritis

2000 • 75 citations

Subsets of Macrophages and Dendritic Cells in Nonobese Diabetic Mouse Pancreatic Inflammatory Infiltrates: Correlation with the Development of Diabetes

2000 • 72 citations

Bcl-2 expression in pancreas development and pancreatic cancer progression

2001 • 66 citations

Islet Abnormalities Associated with an Early Influx of Dendritic Cells and Macrophages in NOD and NODscid Mice

2000 • 65 citations

Two Different Types of Sialoadenitis in the NOD- and MRL/lpr Mouse Models for Sjögren's Syndrome: A Differential Role for Dendritic Cells in the Initiation of Sialoadenitis?

2000 • 64 citations

The innervation of the pancreas of the mouse, with special reference to the structure of the peripheral extension of the vegetative nervous system

1956 • 64 citations

Macrophages Are Eliminated from the Injured Peripheral Nerve via Local Apoptosis and Circulation to Regional Lymph Nodes and the Spleen

2001 • 64 citations

Islet injury induces neurotrophin expression in pancreatic cells and reactive gliosis of peri-islet Schwann cells

1998 • 61 citations

Peripherin: an islet antigen that is cross-reactive with nonobese diabetic mouse class II gene products.

1992 • 58 citations

Abnormal Organogenesis in Salivary Gland Development May Initiate Adult Onset of Autoimmune Exocrinopathy

2001 • 55 citations

Abnormalities in dendritic cell and macrophage accumulation in the pancreas of nonobese diabetic (NOD) mice during the early neonatal period.

2002 • 53 citations

Morphological Characteristics of Schwann Cells in the Islets of Langerhans of the Murine Pancreas.

2001 • 52 citations

T Cells of Multiple Sclerosis Patients Target a Common Environmental Peptide that Causes Encephalitis in Mice

2001 • 49 citations

Islet abnormalities in the pathogenesis of autoimmune diabetes

2002 • 44 citations

Fluorescence studies on neural structures and endocrine cells in the pancreas of the cat

1968 • 43 citations

Macrophages during avian optic nerve development: relationship to cell death and differentiation into microglia

1996 • 41 citations

Apoptosis and occurrence of Bcl-2, Bak, Bax, Fas and FasL in the developing and adult rat endocrine pancreas

2000 • 37 citations

Regulation of Fas and FasL expression on rat Schwann cells

2000 • 37 citations

Beta-cell apoptosis in an accelerated model of autoimmune diabetes.

1998 • 36 citations

Splenic Dendritic Cells From the Non-obese Diabetic Mouse Induce a Prolonged Proliferation of Syngeneic T Cells. A Role for an Impaired Apoptosis of NOD T cells?

1999 • 34 citations

Role of Fas/FasL Interaction in Physiology and Pathology: The Good and the Bad

1998 • 32 citations

The role of Fas ligand in vivo as a cause and regulator of pathogenesis

2000 • 32 citations

Beta-cell behaviour during the prediabetic stage. Part II. Non-insulin-dependent and insulin-dependent diabetes mellitus.

1997 • 31 citations

Expression of Bcl-2 and PCNA in Duct Cells After Pancreatic Duct Ligation in Rats

1997 • 30 citations

Distribution of neuropeptide-containing nerve fibers in the human submandibular gland, with special reference to the difference between serous and mucous acini

1997 • 30 citations

Regulation of Fas and FasL expression on rat Schwann cells

2000 • 29 citations

β-Cell Apoptosis in an Accelerated Model of Autoimmune Diabetes

1998 • 29 citations

Enhanced metabolism of arachidonic acid by macrophages from nonobese diabetic (NOD) mice

1992 • 27 citations

Localization of gamma-aminobutyric acid and glutamic acid decarboxylase in the pancreas of the nonobese diabetic mouse.

1996 • 27 citations

Peripherin and neurofilaments: expression and role during neural development.

1993 • 26 citations

Is pancreas development abnormal in the non-obese diabetic mouse, a spontaneous model of type I diabetes?

2001 • 24 citations

Neuro-insular complex type I in the mouse. Re-evaluation of the pancreatic islet as a modified ganglion.

1979 • 24 citations

CD95 and CD95-ligand expression in endocrine pancreas of NOD, NOR and BALB/c mice

1997 • 23 citations

Islet Endocrine-Cell Behavior From Birth Onward in Mice With the Nonobese Diabetic Genetic Background

2001 • 22 citations

Neuro-Insular Complex Type I in the Mouse

1979 • 22 citations

Fas and Fas ligand-mediated apoptosis and its role in autoimmune diabetes

1998 • 20 citations

Neuroinsular Complex Type I: Morphology and Frequency in Lean and Genetically Obese Mice

2001 • 18 citations

Biphasic Development of the Postnatal Mouse Pancreas

1981 • 15 citations

Autoantibodies in Salivary Hypofunction in the NOD Mouse^a,

1998 • 14 citations

Immunohistochemical Analysis of Apoptosis-Related Proteins in Human Embryonic and Fetal Pancreatic Tissues

2000 • 9 citations