CCAAT/enhancer-binding proteins: structure, function and regulation

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

1998 • 1,972 citations

Transcriptional regulation of adipogenesis

2000 • 1,875 citations

Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.

1991 • 1,684 citations

A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family.

1990 • 1,517 citations

C/EBPα induces adipogenesis through PPARγ: a unified pathway

2002 • 1,345 citations

EUKARYOTIC TRANSCRIPTIONAL REGULATORY PROTEINS

1989 • 1,299 citations

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription.

1992 • 1,156 citations

A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the sam mRNA

1991 • 1,019 citations

Isolation of a recombinant copy of the gene encoding C/EBP.

1988 • 1,003 citations

Scissors-Grip Model for DNA Recognition by a Family of Leucine Zipper Proteins

1989 • 996 citations

Cross-Regulation of C/EBPα and PPARγ Controls the Transcriptional Pathway of Adipogenesis and Insulin Sensitivity

1999 • 976 citations

Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein α-deficient mice

1997 • 929 citations

Impaired Energy Homeostasis in C/EBPα Knockout Mice

1995 • 925 citations

Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins.

1995 • 922 citations

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-α (C/EBPα), in acute myeloid leukemia

2001 • 900 citations

Stress-Induced Phosphorylation and Activation of the Transcription Factor CHOP (GADD153) by p38 MAP Kinase

1996 • 893 citations

Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

1993 • 884 citations

Targeted disruption of the Chop gene delays endoplasmic reticulum stress–mediated diabetes

2002 • 858 citations

Biological Role of the CCAAT/Enhancer-binding Protein Family of Transcription Factors

1998 • 799 citations

Defective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene

1997 • 776 citations

The Role of C/EBP Genes in Adipocyte Differentiation

1998 • 736 citations

The DNA Binding Domain of the Rat Liver Nuclear Protein C/EBP Is Bipartite

1989 • 661 citations

The Role of C/EBP Isoforms in the Control of Inflammatory and Native Immunity Functions

1998 • 661 citations

IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to CEBP

1990 • 637 citations

A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro.

1991 • 604 citations

LAP, a novel member of the C/EBP gene family, encodes a liver-enriched transcriptional activator protein.

1990 • 599 citations

Nitric oxide-induced apoptosis in pancreatic β cells is mediated by the endoplasmic reticulum stress pathway

2001 • 594 citations

Induction of Peroxisome Proliferator-Activated Receptor γ during the Conversion of 3T3 Fibroblasts into Adipocytes Is Mediated by C/EBPβ, C/EBPδ, and Glucocorticoids

1996 • 590 citations

Phosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6.

1993 • 587 citations

Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma

1993 • 551 citations

Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages

1995 • 532 citations

C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia

1994 • 528 citations

Ectopic expression of the CCAAT/enhancer-binding protein alpha promotes the adipogenic program in a variety of mouse fibroblastic cells.

1994 • 450 citations

Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs.

1996 • 446 citations

Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)–ATF composite site to regulate Gadd153 expression during the stress response

1999 • 445 citations

CCAAT/enhancer binding protein alpha is sufficient to initiate the 3T3-L1 adipocyte differentiation program.

1994 • 433 citations

Lymphoproliferative disorder and imbalanced T-helper response in C/EBP beta-deficient mice.

1995 • 418 citations

A novel temporal expression pattern of three C/EBP family members in differentiating myelomonocytic cells

1992 • 413 citations

Calcium-Regulated Phosphorylation Within the Leucine Zipper of C/EBPβ

1992 • 398 citations

CCAAT/enhancer binding protein gene promoter: binding of nuclear factors during differentiation of 3T3-L1 preadipocytes.

1991 • 389 citations

cAMP stimulates the C/EBP-related transcription factor rNFIL-6 to trans-locate to the nucleus and induce c-fos transcription.

1991 • 388 citations

An essential role for C/EBPβ in female reproduction

1997 • 387 citations

Transcription factors 1: bZIP proteins.

1995 • 385 citations

Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein ɛ-deficient mice

1997 • 379 citations

Activation and centromeric localization of CCAAT/enhancer-binding proteins during the mitotic clonal expansion of adipocyte differentiation

1999 • 377 citations

CCAAT/enhancer-binding protein mRNA is translated into multiple proteins with different transcription activation potentials.

1993 • 372 citations

Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain

1993 • 345 citations

C/EBPα Arrests Cell Proliferation through Direct Inhibition of Cdk2 and Cdk4

2001 • 344 citations

Dimerization specificity of the leucine zipper-containing bZIP motif on DNA binding: prediction and rational design.

1993 • 335 citations

CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest.

1994 • 331 citations

A member of the C/EBP family, NF-IL6 beta, forms a heterodimer and transcriptionally synergizes with NF-IL6.

1992 • 327 citations

Antisense CCAAT/enhancer-binding protein RNA suppresses coordinate gene expression and triglyceride accumulation during differentiation of 3T3-L1 preadipocytes.

1992 • 324 citations

The p50 subunit of NF-kappa B associates with the NF-IL6 transcription factor.

1992 • 324 citations

C/EBPα is required for differentiation of white, but not brown, adipose tissue

2001 • 323 citations

Structural Analyses of DNA Recognition by the AML1/Runx-1 Runt Domain and Its Allosteric Control by CBFβ

2001 • 319 citations

A 30-kDa alternative translation product of the CCAAT/enhancer binding protein alpha message: transcriptional activator lacking antimitotic activity.

1993 • 313 citations

c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II.

1994 • 313 citations

Differential expression of three C/EBP isoforms in multiple tissues during the acute phase response.

1992 • 313 citations

Stress-Induced Binding of the Transcription Factor CHOP to a Novel DNA Control Element

1996 • 305 citations

DNA Binding Specificity of the CCAAT/Enhancer-binding Protein Transcription Factor Family

1996 • 300 citations

Macrophage differentiation-specific expression of NF-IL6, a transcription factor for interleukin-6

1992 • 299 citations

Retinoic Acid Blocks Adipogenesis by Inhibiting C/EBPβ-Mediated Transcription

1997 • 293 citations

Increased Hepatic Cell Proliferation and Lung Abnormalities in Mice Deficient in CCAAT/Enhancer Binding Protein α

1996 • 289 citations

CCAAT enhancer- binding protein beta is required for normal hepatocyte proliferation in mice after partial hepatectomy.

1998 • 274 citations

Molecular cloning of a transcription factor, AGP/EBP, that belongs to members of the C/EBP family.

1990 • 274 citations

Role of the CCAAT Enhancer Binding Proteins (C/EBPs) in Adipocyte Differentiation

1999 • 273 citations

Ig/EBP-1: a ubiquitously expressed immunoglobulin enhancer binding protein that is similar to C/EBP and heterodimerizes with C/EBP.

1990 • 272 citations

C/ATF, a member of the activating transcription factor family of DNA-binding proteins, dimerizes with CAAT/enhancer-binding proteins and directs their binding to cAMP response elements.

1993 • 272 citations

Amino acid regulation of gene expression

2000 • 269 citations

Is CCAAT/enhancer-binding protein a central regulator of energy metabolism?

1989 • 266 citations

The C/EBPβ transcription factor regulates epithelial cell proliferation and differentiation in the mammary gland

1998 • 260 citations

C/EBPβ, but not C/EBPα, is essential for ductal morphogenesis, lobuloalveolar proliferation, and functional differentiation in the mouse mammary gland

1998 • 254 citations

Cognate DNA Binding Specificity Retained After Leucine Zipper Exchange Between GCN4 and C/EBP

1989 • 237 citations

CCAAT/Enhancer Binding Protein α Regulates p21 Protein and Hepatocyte Proliferation in Newborn Mice

1997 • 236 citations

The C/EBP Family of Transcription Factors

1995 • 236 citations

Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153).

1995 • 230 citations

CRP2 (C/EBP beta) contains a bipartite regulatory domain that controls transcriptional activation, DNA binding and cell specificity.

1995 • 230 citations

Novel mechanism of C/EBP beta (NF-M) transcriptional control: activation through derepression.

1994 • 225 citations

Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region.

1994 • 207 citations

Amino Acid Limitation Induces Expression of CHOP, a CCAAT/Enhancer Binding Protein-related Gene, at Both Transcriptional and Post-transcriptional Levels

1997 • 203 citations

Induction of the mammalian stress response gene GADD153 by oxidative stress: role of AP-1 element

1996 • 202 citations

Glycogen Synthase Kinase 3 Is an Insulin-Regulated C/EBPα Kinase

1999 • 201 citations

CCAAT/enhancer binding protein-β is a mediator of keratinocyte survival and skin tumorigenesis involving oncogenic Ras signaling

2001 • 196 citations

Amino Acids Control Mammalian Gene Transcription: Activating Transcription Factor 2 Is Essential for the Amino Acid Responsiveness of the CHOP Promoter

2000 • 195 citations

The NF-M transcription factor is related to C/EBP beta and plays a role in signal transduction, differentiation and leukemogenesis of avian myelomonocytic cells.

1993 • 195 citations

Neutrophil-specific Granule Deficiency Results from a Novel Mutation with Loss of Function of the Transcription Factor CCAAT/Enhancer Binding Protein ε

1999 • 194 citations

Transcriptional repression of the C/EBP-alpha and GLUT4 genes in 3T3-L1 adipocytes by tumor necrosis factor-alpha. Regulations is coordinate and independent of protein synthesis.

1992 • 194 citations

CREB Controls LAP/C/EBPβ Transcription

1997 • 189 citations

CCAAT/enhancer binding protein ε is a potential retinoid target gene in acute promyelocytic leukemia treatment

1999 • 188 citations

Transcriptional activation of the mouse obese (ob) gene by CCAAT/enhancer binding protein alpha.

1996 • 186 citations

A Novel, Myeloid Transcription Factor, C/EBPε, Is Upregulated During Granulocytic, But Not Monocytic, Differentiation

1997 • 185 citations

CCAAT/enhancer binding protein ɛ is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicing

1997 • 185 citations

Pro-inflammatory cytokines induce the transcription factors C/EBP? and C/EBP? in astrocytes

2000 • 181 citations

Disruption of the c/ebpα Gene in Adult Mouse liver

1997 • 180 citations

The two C/EBP isoforms, IL6DBP/NFIL6 and CEBP6δ/NFIL63, are induced by IL6β to promote acute phase gene transcription via different mechanisms

1993 • 176 citations

Fornix-Dependent Induction of Hippocampal CCAAT Enhancer-Binding Protein β and δ Co-Localizes with Phosphorylated cAMP Response Element-Binding Protein and Accompanies Long-Term Memory Consolidation

2001 • 176 citations

CUG repeat binding protein (CUGBP1) interacts with the 5' region of C/EBP mRNA and regulates translation of C/EBP isoforms

1999 • 170 citations

C/EBPβ Phosphorylation by RSK Creates a Functional XEXD Caspase Inhibitory Box Critical for Cell Survival

2001 • 166 citations

Phosphorylation of Rat Serine 105 or Mouse Threonine 217 in C/EBPβ Is Required for Hepatocyte Proliferation Induced by TGFα

1999 • 165 citations

Role of C/EBP homologous protein (CHOP-10) in the programmed activation of CCAAT/enhancer-binding protein-β during adipogenesis

2000 • 164 citations

Interleukin-6-Specific Activation of the C/EBPδ Gene in Hepatocytes Is Mediated by Stat3 and Sp1

1998 • 163 citations

Mechanism of c-Myb–C/EBPβ Cooperation from Separated Sites on a Promoter

2002 • 160 citations

The Induction of Cyclooxygenase-2 mRNA in Macrophages Is Biphasic and Requires both CCAAT Enhancer-binding protein β (C/EBPβ) and C/EBPδ Transcription Factors

2001 • 159 citations

Autoregulation of the Human C/EBPα Gene by Stimulation of Upstream Stimulatory Factor Binding

1995 • 156 citations

McBindall—A Better Name for CCAAT/Enhancer Binding Proteins?

2001 • 156 citations

Selectively enhanced contextual fear conditioning in mice lacking the transcriptional regulator CCAAT/enhancer binding protein δ

1998 • 151 citations

The DNA Binding Activity of C/EBP Transcription Factors Is Regulated in the G1 Phase of the Hepatocyte Cell Cycle

1995 • 151 citations

C/EBPβ Modulates the Early Events of Keratinocyte Differentiation Involving Growth Arrest and Keratin 1 and Keratin 10 Expression

1999 • 149 citations

Tumor necrosis factor-induced reversal of adipocytic phenotype of 3T3-L1 cells is preceded by a loss of nuclear CCAAT/enhancer binding protein (C/EBP).

1992 • 149 citations

Regulation of Leptin Promoter Function by Sp1, C/EBP, and a Novel Factor¹

1998 • 145 citations

Protein kinase A and C site-specific phosphorylations of LAP (NF-IL6) modulate its binding affinity to DNA recognition elements.

1994 • 144 citations

Cloning of the Novel Human Myeloid-Cell-Specific C/EBP-ε Transcription Factor

1997 • 141 citations

Three levels of functional interaction determine the activity of CCAAT/enhancer binding protein-alpha on the serum albumin promoter.

1994 • 138 citations

Repressive Effect of Sp1 on the C/EBPα Gene Promoter: Role in Adipocyte Differentiation

1999 • 137 citations

Upregulation of Interleukin 6 and Granulocyte Colony-Stimulating Factor Receptors by Transcription Factor CCAAT Enhancer Binding Protein α (C/EBPα) Is Critical for Granulopoiesis

1998 • 134 citations

Inhibition of cell proliferation by C/EBPα occurs in many cell types, does not require the presence of p53 or Rb, and is not affected by large T-antigen

1995 • 133 citations

Antioxidant-induced Nuclear Translocation of CCAAT/Enhancer-binding Protein β

1997 • 133 citations

Ig/EBP (C/EBPγ) is a transdominant negative inhibitor of C/EBP family transcriptional activators

1995 • 132 citations

Isolation, characterization and chromosomal localization of the human GADD153 gene

1992 • 130 citations

Glucocorticoids reciprocally regulate expression of the CCAAT/enhancer-binding protein alpha and delta genes in 3T3-L1 adipocytes and white adipose tissue.

1994 • 129 citations

Phosphorylation of CCAAT-enhancer binding protein by protein kinase C attenuates site-selective DNA binding.

1992 • 124 citations

Neutrophil-specific granule deficiency: homozygous recessive inheritance of a frameshift mutation in the gene encoding transcription factor CCAAT/enhancer binding protein–ε

2001 • 124 citations

The Role of C/EBPε in the Terminal Stages of Granulocyte Differentiation

2001 • 121 citations

Isolation and characterization of the hamster gadd153 gene. Activation of promoter activity by agents that damage DNA.

1990 • 120 citations

Identification of C/EBP basic region residues involved in DNA sequence recognition and half-site spacing preference.

1993 • 119 citations

Serum amyloid A gene expression under acute-phase conditions involves participation of inducible C/EBP-beta and C/EBP-delta and their activation by phosphorylation.

1994 • 118 citations

Modulation of the Murine Peroxisome Proliferator-activated Receptor γ2 Promoter Activity by CCAAT/Enhancer-binding Proteins

2000 • 115 citations

High level activity of the mouse CCAAT/enhancer binding protein (C/EBPα) gene promoter involves autoregulation and several ubiquitous transcription factors

1993 • 110 citations

C/EBPα Regulates Generation of C/EBPβ Isoforms through Activation of Specific Proteolytic Cleavage

1999 • 109 citations

A Novel Human CCAAT/Enhancer Binding Protein Gene, C/EBPϵ, Is Expressed in Cells of Lymphoid and Myeloid Lineages and Is Localized on Chromosome 14q11.2 Close to the T-Cell Receptor α/δ Locus

1996 • 109 citations

C/EBPα Regulates Formation of S-Phase-Specific E2F-p107 Complexes in Livers of Newborn Mice

1999 • 108 citations

CCAAT/Enhancer Binding Protein ɛ Is Critical for Effective Neutrophil-Mediated Response to Inflammatory Challenge

1999 • 105 citations

Nuclear export of phosphorylated C/EBPbeta mediates the inhibition of albumin expression by TNF-alpha

2001 • 104 citations

Tumor Necrosis Factor α Promotes Nuclear Localization of Cytokine-inducible CCAAT/Enhancer Binding Protein Isoforms in Hepatocytes

1996 • 104 citations

Interleukin-6-induced Tethering of STAT3 to the LAP/C/EBPβ Promoter Suggests a New Mechanism of Transcriptional Regulation by STAT3

2001 • 103 citations

Molecular Cloning, Sequence, and Expression Patterns of the Human Gene Encoding CCAAT/Enhancer Binding Protein α (C/EBPα)

1995 • 101 citations

A role for CCAAT/enhancer binding protein beta-liver-enriched inhibitory protein in mammary epithelial cell proliferation.

2001 • 98 citations

Vasoactive intestinal peptide, pituitary adenylate cyclase-activating peptide, and noradrenaline induce the transcription factors CCAAT/enhancer binding protein (C/EBP)-beta and C/EBP delta in mouse cortical astrocytes: involvement in cAMP-regulated glycogen metabolism

1996 • 95 citations

Molecular characterization of transcription factors that bind to the cAMP responsive region of the substance P precursor gene. cDNA cloning of a novel C/EBP-related factor

1991 • 92 citations

T<scp>HE</scp> R<scp>OLE OF</scp> C/EBP <scp>IN</scp> N<scp>UTRIENT AND</scp> H<scp>ORMONAL</scp> R<scp>EGULATION OF</scp> G<scp>ENE</scp> E<scp>XPRESSION</scp>

2001 • 91 citations

Hypoglycemia and impaired hepatic glucose production in mice with a deletion of the C/EBPβ gene

1999 • 90 citations

CCAAT/Enhancer Binding Protein β Is a Neuronal Transcriptional Regulator Activated by Nerve Growth Factor Receptor Signaling

1998 • 89 citations

Myeloid Transcription Factor C/EBPɛ Is Involved in the Positive Regulation of Lactoferrin Gene Expression in Neutrophils

1999 • 88 citations

Early responses of trans-activating factors to growth hormone in preadipocytes: differential regulation of CCAAT enhancer-binding protein-beta (C/EBP beta) and C/EBP delta.

1995 • 86 citations

C/EBP-related protein 2 confers lipopolysaccharide-inducible expression of interleukin 6 and monocyte chemoattractant protein 1 to a lymphoblastic cell line.

1994 • 85 citations

An "attenuator domain" is sandwiched by two distinct transactivation domains in the transcription factor C/EBP.

1991 • 85 citations

CCAAT/Enhancer-binding Protein β Plays a Regulatory Role in Differentiation and Apoptosis of Neuroblastoma Cells

2002 • 85 citations

Induction of GADD153, a CCAAT/enhancer-binding protein (C/EBP)-related gene, during the acute phase response in rats. Evidence for the involvement of C/EBPs in regulating its expression.

1994 • 85 citations

DIFFERENTIAL REGULATION OF MACROPHAGE CCAAT-ENHANCER BINDING PROTEIN ISOFORMS BY LIPOPOLYSACCHARIDE AND CYTOKINES

2000 • 85 citations

C/EBPalpha triggers proteasome-dependent degradation of cdk4 during growth arrest

2002 • 84 citations

Inhibition of CCAAT/Enhancer-binding Protein α and β Translation by Upstream Open Reading Frames

1998 • 83 citations

Insulin Suppresses Transactivation by CAAT/Enhancer-binding Proteins β (C/EBPβ)

2001 • 82 citations

CCAAT/Enhancer-binding Protein Activates the CD14 Promoter and Mediates Transforming Growth Factor β Signaling in Monocyte Development

1999 • 81 citations

Derepression of the C/EBPα gene during adipogenesis: Identification of AP-2α as a repressor

1998 • 80 citations

Translation start site multiplicity of the CCAAT/enhancer binding protein α mRNA is dictated by a small 5′ open reading frame

1994 • 79 citations

Mice with a Deletion in the Gene for CCAAT/Enhancer-binding Protein β Have an Attenuated Response to cAMP and Impaired Carbohydrate Metabolism

2001 • 78 citations

Runt Domain Factor (Runx)-dependent Effects on CCAAT/ Enhancer-binding Protein δ Expression and Activity in Osteoblasts

2000 • 77 citations

Molecular Cloning of a Transcription Factor, AGP/EBP, That Belongs to Members of the C/EBP Family

1990 • 76 citations

Signal Transducer and Activator of Transcription 3 Activates CCAAT Enhancer-binding Protein δ Gene Transcription in G0Growth-arrested Mouse Mammary Epithelial Cells and in Involuting Mouse Mammary Gland

2000 • 76 citations

CHOP gene expression in response to endoplasmic-reticular stress requires NFY interaction with different domains of a conserved DNA-binding element

2000 • 75 citations

Cell lineage-specific and differentiation-dependent patterns of CCAAT/enhancer binding protein alpha expression in the gut epithelium of normal and transgenic mice.

1993 • 73 citations

Generation of Truncated C/EBPβ Isoforms by in VitroProteolysis

2000 • 71 citations

Induction of the C/EBP Gene by Dexamethasone and Glucagon in Primary-Cultured Rat Hepatocytes

1996 • 70 citations

Hypoglycemia-associated Hyperammonemia Caused by Impaired Expression of Ornithine Cycle Enzyme Genes in C/EBPα Knockout Mice

1998 • 70 citations

C/EBPε Is a Myeloid-specific Activator of Cytokine, Chemokine, and Macrophage-Colony-stimulating Factor Receptor Genes

1998 • 69 citations

Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region

1994 • 68 citations

Drosophila C/EBP: a tissue-specific DNA-binding protein required for embryonic development.

1992 • 67 citations

Expressions of CCAAT/Enhancer-binding Proteins β and δ and Their Activities Are Intensified by cAMP Signaling as Well as Ca2+/Calmodulin Kinases Activation in Hippocampal Neurons

1998 • 66 citations

Impairment of Natural Killer Cytotoxic Activity and Interferon γ Production in Ccaat/Enhancer Binding Protein γ–Deficient Mice

1999 • 65 citations

C/EBP α and C/EBP δ Activate the Clara Cell Secretory Protein Gene through Interaction with Two Adjacent C/EBP-Binding Sites

2000 • 59 citations

Molecular cloning, genetic mapping, and expression analysis of four zebrafish c/ebp genes

2001 • 59 citations

Autoregulation enables different pathways to control CCAAT/enhancer binding protein β (C/EBPβ) transcription

2001 • 55 citations

Identification of Transcriptional Activation and Repression Domains in Human CCAAT/Enhancer-binding Protein ε

1998 • 54 citations

Translational induction of LIP during acute phase response leads to repression of C/EBP alpha mRNA

2000 • 53 citations

CCAAT/Enhancer-Binding Protein Gene Expression Is Mediated by APRF/STAT3

1997 • 52 citations

Autocrine Signals Control CCAAT/Enhancer Binding Protein β Expression, Localization, and Activity in Macrophages

1998 • 49 citations

A novel myeloid-restricted zebrafish CCAAT/enhancer-binding protein with a potent transcriptional activation domain

2001 • 45 citations

Mice lacking CCAAT/enhancer-binding protein-? show hyperproliferation of alveolar type II cells and increased surfactant protein mRNAs

2001 • 44 citations

Hepatocytes Deficient in CCAAT/Enhancer Binding Protein α (C/EBPα) Exhibit both Hepatocyte and Biliary Epithelial Cell Character

1998 • 43 citations

Expression of the genes encoding CCAAT-enhancer binding protein isoforms in the mouse mammary gland during lactation and involution

1998 • 42 citations

Transcription of a Minimal Promoter from the NF-IL6 Gene Is Regulated by CREB/ATF and SP1 Proteins in U937 Promonocytic Cells

1998 • 42 citations

Repression of transcription mediated by dual elements in the CCAAT/enhancer binding protein α gene

1997 • 40 citations

Sequential repression and activation of the CCAAT enhancer-binding protein-α (C/EBPα) gene during adipogenesis

2000 • 40 citations

Macrophage functional maturation and cytokine production are impaired in C/EBPε-deficient mice

2002 • 39 citations

Identification of C/EBP Basic Region Residues Involved in DNA Sequence Recognition and Half-Site Spacing Preference

1993 • 38 citations

Autoregulated Induction of the Acute-Phase Response Transcription Factor Gene,agp/ebp

1995 • 36 citations

Myc Inhibits CCAAT/Enhancer‐Binding Protein α‐Gene Expression in HIB‐1B Hibernoma Cells Through Interactions with the Core Promoter Region

1995 • 33 citations

Regulated Nuclear-Cytoplasmic Localization of CCAAT/ Enhancer-binding Protein δ in Osteoblasts

2001 • 32 citations

An “Attenuator Domain” Is Sandwiched by Two Distinct Transactivation Domains in the Transcription Factor C/EBP

1991 • 31 citations

Analysis of the Xenopus laevis CCAAT-enhancer binding protein alpha gene promoter demonstrates species-specific differences in the mechanisms for both auto-activation and regulation by Sp1

2001 • 31 citations

Transcriptional Regulation of C/EBPδ in G0 Growth-Arrested Mouse Mammary Epithelial Cells

1999 • 30 citations

Stimulus- and cell-type-specific regulation of CCAAT-enhancer binding protein isoforms in glomerular mesangial cells by lipopolysaccharide and cytokines

2000 • 30 citations

Characterization of the Promoter Region of the Rat CCAAT/Enhancer-Binding Protein α Gene and Regulation by Thyroid Hormone in Rat Immortalized Brown Adipocytes¹

2000 • 30 citations

Induction of the C/EBP Homologous Protein (CHOP) by Amino Acid Deprivation Requires Insulin-Like Growth Factor I, Phosphatidylinositol 3-Kinase, and Mammalian Target of Rapamycin Signaling**This work was supported by NIH Grants CA-42572 and CA-85492. Sequencing was carried out by the DNA Sequencing Shared Resource (Grant P30-CA-68485). Data presentation was performed in part through the use of the Vanderbilt University Medical Center Cell Imaging Resource (Grants CA-68485 and DK-20593).

2001 • 28 citations

CCAAT/Enhancer-Binding Protein δ Gene Expression Is Mediated by Autoregulation through Downstream Binding Sites

1998 • 28 citations

CHOP/GADD153 Gene Expression Response to Cellular Stresses Inhibited by Prior Exposure to Ultraviolet Light Wavelength Band C (UVC)

2000 • 28 citations

The v-Myb oncoprotein activates C/EBPβ expression by stimulating an autoregulatory loop at the C/EBPβ promoter

1999 • 27 citations

A Short Conserved Motif Is Required for Repressor Domain Function in the Myeloid-specific Transcription Factor CCAAT/Enhancer-binding Protein ε

1999 • 27 citations

Characterization and expression of C/EBP‐like genes in the liver of Rana catesbeiana tadpoles during spontaneous and thyroid hormone‐induced metamorphosis

1994 • 24 citations

Serum Amyloid A Gene Expression under Acute-Phase Conditions Involves Participation of Inducible C/EBP-β and C/EBP-δ and Their Activation by Phosphorylation

1994 • 21 citations

Location analysis of DNA‐bound proteins at the whole‐genome level: untangling transcriptional regulatory networks

2001 • 21 citations

Characterisation and developmental regulation of the Xenopus laevis CCAAT-enhancer binding protein β gene

1998 • 20 citations

Molecular Characterization of the Xenopus CCAAT-Enhancer Binding Protein β Gene Promoter

2001 • 17 citations

Structural and Functional Studies of CCAAT/Enhancer-binding Protein ε

2001 • 14 citations

Molecular cloning and expression of CCAAT/enhancer binding proteins in Japanese flounder Paralichthys olivaceus

2002 • 13 citations

The Ovine CCAAT-Enhancer Binding Protein δ Gene: Cloning, Characterization, and Species-Specific Autoregulation

2000 • 13 citations

Regulation of CCAAT/Enhancer Binding Proteinα (C/EBPα) Gene Expression by Thiazolidinediones in 3T3-L1 Adipocytes

1998 • 11 citations

Nucleotide sequence of ovine C/EBPepsilon gene.

1998 • 4 citations

Deleted Work

1955 • 0 citations