Amino Acid Limitation Induces Expression of CHOP, a CCAAT/Enhancer Binding Protein-related Gene, at Both Transcriptional and Post-transcriptional Levels

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Measurement of protein using bicinchoninic acid

1985 • 17,516 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Basic Methods in Molecular Biology

1986 • 3,284 citations

Current Protocols in Molecular Biology

2001 • 2,451 citations

Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.

1991 • 1,684 citations

Regulating the fate of mRNA: The control of cellular iron metabolism

1993 • 1,233 citations

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription.

1992 • 1,156 citations

Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

1993 • 884 citations

CCAAT-Enhancer Binding Protein: A Component of a Differentiation Switch

1991 • 733 citations

Signals from the Stressed Endoplasmic Reticulum Induce C/EBP-Homologous Protein (CHOP/GADD153)

1996 • 671 citations

Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein.

1989 • 641 citations

GCN4 protein, synthesize in vitro, binds HIS3 regulatory sequences: Implications for general control of amino acid biosynthetic genes in yeast

1985 • 496 citations

Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae

1988 • 449 citations

Regulatory and molecular aspects of mammalian amino acid transport

1994 • 368 citations

CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest.

1994 • 331 citations

Stress-Induced Binding of the Transcription Factor CHOP to a Novel DNA Control Element

1996 • 305 citations

Regulation of lipogenic enzyme gene expression by nutrients and hormones

1994 • 268 citations

A novel effector domain from the RNA-binding protein TLS or EWS is required for oncogenic transformation by CHOP.

1994 • 266 citations

Is CCAAT/enhancer-binding protein a central regulator of energy metabolism?

1989 • 266 citations

Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153).

1995 • 230 citations

ATTENUATION IN AMINO ACID BIOSYNTHETIC OPERONS

1982 • 218 citations

Induction of the mammalian stress response gene GADD153 by oxidative stress: role of AP-1 element

1996 • 202 citations

S26 ribosomal protein RNA: an invariant control for gene regulation experiments in eucaryotic cells and tissues

1993 • 198 citations

Recent Advances in Mammalian Amino Acid Transport

1993 • 194 citations

Transcriptional control of metabolic regulation genes by carbohydrates

1994 • 191 citations

Regulation of the C/EBP-related gene gadd153 by glucose deprivation.

1993 • 190 citations

Activation of the gadd153 promoter by genotoxic agents: a rapid and specific response to DNA damage.

1992 • 175 citations

Metabolic Regulation of Gene Transcription in Mammals

1995 • 160 citations

Effect of amino acid limitation on the expression of 19 genes in rat hepatoma cells

1994 • 140 citations

Isolation, characterization and chromosomal localization of the human GADD153 gene

1992 • 130 citations

Calcium ionophore A23187 induces expression of the growth arrest and DNA damage inducible CCAAT/enhancer-binding protein (C/EBP)-related gene, gadd153. Ca2+ increases transcriptional activity and mRNA stability.

1992 • 129 citations

Gene expression: nutrient control of pre‐ and posttranscriptional events ¹

1992 • 125 citations

Leucine, glucose, and energy metabolism after 3 days of fasting in healthy human subjects

1987 • 114 citations

Physical and Functional Association between GADD153 and CCAAT/Enhancer-binding Protein β during Cellular Stress

1996 • 113 citations

Cis- and trans-acting elements involved in amino acid regulation of asparagine synthetase gene expression.

1993 • 108 citations

Induction of insulin-like growth factor binding protein-1 gene expression in liver of protein-restricted rats and in rat hepatoma cells limited for a single amino acid.

1993 • 99 citations

Regulation of asparagine synthetase gene expression by amino acid starvation.

1991 • 92 citations

Induction of GADD153, a CCAAT/enhancer-binding protein (C/EBP)-related gene, during the acute phase response in rats. Evidence for the involvement of C/EBPs in regulating its expression.

1994 • 85 citations

Cloning of rat asparagine synthetase and specificity of the amino acid-dependent control of its mRNA content

1994 • 71 citations

Review: Amino Acid Metabolism in Thermal Burns

1989 • 70 citations

In Differentiating Mouse Myoblasts DNA Methyltransferase Is Posttranscriptionally and Posttranslationally Regulated

1996 • 58 citations

Deprivation of a Single Amino Acid Induces Protein SynthesisDependent Increases in c-jun, c-myc, and Ornithine Decarboxylase mRNAs in Chinese Hamster Ovary Cells

1990 • 51 citations

Promoter and 11-kilobase upstream enhancer elements responsible for hepatoma cell-specific expression of the rat ornithine transcarbamylase gene.

1990 • 51 citations

Nuclear retention of the induced mRNA following amino acid-dependent transcriptional regulation of mammalian ribosomal proteins L17 and S25

1994 • 46 citations

In vitro analysis of the rat liver-type arginase promoter

1991 • 36 citations

The carbamyl phosphate synthetase promoter contains multiple binding sites for C/EBP-related proteins

1992 • 33 citations