Ig/EBP (C/EBPγ) is a transdominant negative inhibitor of C/EBP family transcriptional activators

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

PCR protocols — A guide to methods and applications

1990 • 10,078 citations

A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family.

1990 • 1,517 citations

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription.

1992 • 1,156 citations

A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the sam mRNA

1991 • 1,019 citations

Scissors-Grip Model for DNA Recognition by a Family of Leucine Zipper Proteins

1989 • 996 citations

CCAAT-Enhancer Binding Protein: A Component of a Differentiation Switch

1991 • 733 citations

Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents.

1989 • 698 citations

Jun-B differs in its biological properties from, and is a negative regulator of, c-Jun

1989 • 698 citations

Differential transcriptional activation by Oct-1 and Oct-2: Interdependent activation domains induce Oct-2 phosphorylation

1990 • 696 citations

The DNA Binding Domain of the Rat Liver Nuclear Protein C/EBP Is Bipartite

1989 • 661 citations

CREM gene: Use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription

1991 • 655 citations

Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein.

1989 • 641 citations

IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to CEBP

1990 • 637 citations

Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses.

1987 • 631 citations

A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro.

1991 • 604 citations

LAP, a novel member of the C/EBP gene family, encodes a liver-enriched transcriptional activator protein.

1990 • 599 citations

IL‐6 and NF‐IL6 in Acute‐Phase Response and Viral Infection

1992 • 540 citations

The interplay of DNA-binding proteins on the promoter of the mouse albumin gene

1987 • 532 citations

Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages

1995 • 532 citations

Genomic structure of the human monocyte-derived neutrophil chemotactic factor IL-8.

1989 • 515 citations

The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth.

1994 • 484 citations

A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity

1991 • 436 citations

Dimerization specificity of the leucine zipper-containing bZIP motif on DNA binding: prediction and rational design.

1993 • 335 citations

A member of the C/EBP family, NF-IL6 beta, forms a heterodimer and transcriptionally synergizes with NF-IL6.

1992 • 327 citations

Reciprocal Regulation of Adipogenesis by Myc and C/EBPα

1992 • 296 citations

Constitutive and interleukin-1 (IL-1)-inducible factors interact with the IL-1-responsive element in the IL-6 gene.

1990 • 283 citations

More is better: Activators and repressors from the same gene

1992 • 280 citations

Molecular cloning of a transcription factor, AGP/EBP, that belongs to members of the C/EBP family.

1990 • 274 citations

Ig/EBP-1: a ubiquitously expressed immunoglobulin enhancer binding protein that is similar to C/EBP and heterodimerizes with C/EBP.

1990 • 272 citations

C/ATF, a member of the activating transcription factor family of DNA-binding proteins, dimerizes with CAAT/enhancer-binding proteins and directs their binding to cAMP response elements.

1993 • 272 citations

The human haptoglobin gene promoter: interleukin-6-responsive elements interact with a DNA-binding protein induced by interleukin-6.

1989 • 196 citations

Regulation of the C/EBP-related gene gadd153 by glucose deprivation.

1993 • 190 citations

C/EBP proteins activate transcription from the human immunodeficiency virus type 1 long terminal repeat in macrophages/monocytes

1995 • 174 citations

Identification of two polypeptide segments of CCAAT/enhancer-binding protein required for transcriptional activation of the serum albumin gene.

1990 • 172 citations

Three levels of functional interaction determine the activity of CCAAT/enhancer binding protein-alpha on the serum albumin promoter.

1994 • 138 citations

Transcriptional repressor ZF5 identifies a new conserved domain in zina finger proteins

1993 • 120 citations

The gadd and MyD Genes Define a Novel Set of Mammalian Genes Encoding Acidic Proteins That Synergistically Suppress Cell Growth

1994 • 119 citations

Cell-specific transcriptional control of the mouse DNA-binding protein mC/EBP.

1989 • 103 citations

Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer.

1992 • 98 citations

Identification of sequences responsible for acute-phase induction of human C-reactive protein

1988 • 87 citations

Binding in vitro of multiple cellular proteins to immunoglobulin heavy-chain enhancer DNA.

1986 • 80 citations

Molecular Cloning of a Transcription Factor, AGP/EBP, That Belongs to Members of the C/EBP Family

1990 • 76 citations

Molecular cloning of two C/EBP-related proteins that bind to the promoter and the enhancer of the α₁-fetoprotein gene. Further analysis of C/EBPβ and C/EBPγ

1992 • 69 citations

Constitutive and Interleukin-1 (IL-1)-Inducible Factors Interact with the IL-1-Responsive Element in the IL-6 Gene

1990 • 58 citations

Complex protein binding within the mouse immunoglobulin heavy-chain enhancer.

1987 • 55 citations

Limited expression of C/EBP family proteins during B lymphocyte development. Negative regulator Ig/EBP predominates early and activator NF-IL-6 is induced later.

1994 • 46 citations

The basic helix-loop-helix-zipper domain of TFE3 mediates enhancer-promoter interaction.

1994 • 45 citations

Binding In Vitro of Multiple Cellular Proteins to Immunoglobulin Heavy-Chain Enhancer DNA

1986 • 43 citations

Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site.

1994 • 40 citations

Molecular cloning of cDNA and a chromosomal gene encoding GPE1‐BP, a nuclear protein which binds to granulocyte colony‐stimulating factor promoter element 1

1991 • 39 citations

The C/EBP family of transcriptional activators is functionally important for Ig VH promoter activity in vivo and in vitro.

1992 • 38 citations

Complex Protein Binding within the Mouse Immunoglobulin Heavy-Chain Enhancer

1987 • 32 citations

Purified µEBP-E Binds to Immunoglobulin Enhancers and Promoters

1988 • 29 citations

PMA-responsive 5' flanking sequences of the human TNF gene.

1989 • 26 citations

The Basic Helix-Loop-Helix-Zipper Domain of TFE3 Mediates Enhancer-Promoter Interaction

1994 • 13 citations