C/EBPalpha triggers proteasome-dependent degradation of cdk4 during growth arrest

CDK inhibitors: positive and negative regulators of G1-phase progression

1999 • 6,003 citations

The regulation of E2F by pRB-family proteins

1998 • 2,297 citations

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1995 • 2,115 citations

Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.

1991 • 1,684 citations

Impaired Energy Homeostasis in C/EBPα Knockout Mice

1995 • 925 citations

Biological Role of the CCAAT/Enhancer-binding Protein Family of Transcription Factors

1998 • 799 citations

The Role of C/EBP Genes in Adipocyte Differentiation

1998 • 736 citations

The Role of C/EBP Isoforms in the Control of Inflammatory and Native Immunity Functions

1998 • 661 citations

Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein.

1989 • 641 citations

Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4.

1996 • 475 citations

Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs.

1996 • 446 citations

CCAAT/enhancer-binding protein alpha (C/EBP alpha) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein.

1996 • 393 citations

Targeted Disruption of CDK4 Delays Cell Cycle Entry with Enhanced p27^Kip1 Activity

1999 • 385 citations

C/EBPα Arrests Cell Proliferation through Direct Inhibition of Cdk2 and Cdk4

2001 • 344 citations

Increased Hepatic Cell Proliferation and Lung Abnormalities in Mice Deficient in CCAAT/Enhancer Binding Protein α

1996 • 289 citations

CCAAT/Enhancer Binding Protein α Regulates p21 Protein and Hepatocyte Proliferation in Newborn Mice

1997 • 236 citations

A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 alpha-subunit of the 20S proteasome

2001 • 235 citations

Physical Interaction of Mammalian CDC37 with CDK4

1996 • 135 citations

Inhibition of cell proliferation by C/EBPα occurs in many cell types, does not require the presence of p53 or Rb, and is not affected by large T-antigen

1995 • 133 citations

A Proteasome Howdunit

2000 • 129 citations

Glucocorticoids Stimulate p21 Gene Expression by Targeting Multiple Transcriptional Elements within a Steroid Responsive Region of the p21 Promoter in Rat Hepatoma Cells

1998 • 126 citations

C/EBPα Regulates Formation of S-Phase-Specific E2F-p107 Complexes in Livers of Newborn Mice

1999 • 108 citations

Direct inhibition of G1 cdk kinase activity by MyoD promotes myoblast cell cycle withdrawal and terminal differentiation

1999 • 103 citations

Cell cycle transition under stress conditions controlled by vertebrate heat shock factors

2001 • 91 citations

Interaction between Cdc37 and Cdk4 in human cells

1997 • 90 citations

Genetic Evidence for the Interactions of Cyclin D1 and p27^Kip1 in Mice

2001 • 87 citations

Separation of C/EBPα-mediated proliferation arrest and differentiation pathways

1999 • 61 citations

Adenovirus-mediated Transfer of CCAAT/Enhancer-binding Protein-α Identifies a Dominant Antiproliferative Role for This Isoform in Hepatocytes

1996 • 51 citations

Lack of C/EBP? gene expression results in increased DNA synthesis and an increased frequency of immortalization of freshly isolated mice hepatocytes

1998 • 45 citations