Lymphoproliferative disorder and imbalanced T-helper response in C/EBP beta-deficient mice.

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

1989 • 7,558 citations

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

Interleukin-10-deficient mice develop chronic enterocolitis

1993 • 4,225 citations

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

1987 • 2,368 citations

Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.

1991 • 1,684 citations

A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family.

1990 • 1,517 citations

Tissue-specific in vitro transcription from the mouse albumin promoter

1986 • 1,322 citations

Biological and clinical aspects of interleukin 6

1990 • 1,091 citations

Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide.

1993 • 1,077 citations

A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the sam mRNA

1991 • 1,019 citations

Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's disease

1989 • 870 citations

Interleukin-12 and its role in the generation of TH1 cells

1993 • 869 citations

Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector

1986 • 761 citations

Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion.

1994 • 738 citations

Signaling by the cytokine receptor superfamily: JAKs and STATs

1994 • 659 citations

IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to CEBP

1990 • 637 citations

LAP, a novel member of the C/EBP gene family, encodes a liver-enriched transcriptional activator protein.

1990 • 599 citations

IgG1 plasmacytosis in interleukin 6 transgenic mice.

1989 • 597 citations

Phosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6.

1993 • 587 citations

A novel temporal expression pattern of three C/EBP family members in differentiating myelomonocytic cells

1992 • 413 citations

A systemic lymphoproliferative disorder with morphologic features of Castleman's disease: clinical findings and clinicopathologic correlations in 15 patients.

1985 • 386 citations

Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain

1993 • 345 citations

Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice.

1990 • 338 citations

Alleviation of Systemic Manifestations of Castleman's Disease by Monoclonal Anti-Interleukin-6 Antibody

1994 • 337 citations

A member of the C/EBP family, NF-IL6 beta, forms a heterodimer and transcriptionally synergizes with NF-IL6.

1992 • 327 citations

Macrophage differentiation-specific expression of NF-IL6, a transcription factor for interleukin-6

1992 • 299 citations

Interleukin‐4 and interleukin‐10 inhibit nitric oxide‐dependent macrophage killing of Candida albicans

1993 • 260 citations

Neutralizing antibody to interleukin 4 induces systemic protection and T helper type 1-associated immunity in murine candidiasis.

1992 • 204 citations

Th1 and Th2 cytokine secretion patterns in murine candidiasis: association of Th1 responses with acquired resistance

1991 • 195 citations

Neutralization of IL-10 up-regulates nitric oxide production and protects susceptible mice from challenge with Candida albicans.

1994 • 190 citations

IL-12 is both required and prognostic in vivo for T helper type 1 differentiation in murine candidiasis.

1994 • 140 citations

Development of progressive kidney damage and myeloma kidney in interleukin-6 transgenic mice

1994 • 122 citations

Resistance of Mice Deficient in IL-4 to Retrovirus-Induced Immunodeficiency Syndrome (MAIDS)

1993 • 112 citations

Cure of Murine Candidiasis by Recombinant Soluble Interleukin-4 Receptor

1994 • 99 citations

Reciprocal expression of NF-IL6 and C/EBP in hepatocytes: possible involvement of NF-IL6 in acute phase protein gene expression.

1991 • 83 citations

The C/EBP family of transcriptional activators is functionally important for Ig VH promoter activity in vivo and in vitro.

1992 • 38 citations

The Immune Consequences of Thermal Injury

1981 • 32 citations