The Hallucinogen N,N -Dimethyltryptamine (DMT) Is an Endogenous Sigma-1 Receptor Regulator

Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+

1995 • 5,025 citations

Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival

2007 • 1,593 citations

Trace amines: Identification of a family of mammalian G protein-coupled receptors

2001 • 855 citations

Steroid Binding at σ Receptors Suggests a Link Between Endocrine, Nervous, and Immune Systems

1988 • 531 citations

The Sigma Receptor as a Ligand-Regulated Auxiliary Potassium Channel Subunit

2002 • 385 citations

??-1 Receptor Ligands

2004 • 286 citations

Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors

2005 • 263 citations

The mysterious trace amines: Protean neuromodulators of synaptic transmission in mammalian brain

2006 • 210 citations

Psychotomimetic N -Methylated Tryptamines: Formation in Brain in vivo and in vitro

1972 • 181 citations

Generation and phenotypic analysis of sigma receptor type I (σ1) knockout mice

2003 • 179 citations

Enzymatic Formation of Psychotomimetic Metabolites from Normally Occurring Compounds

1961 • 178 citations

Sigma Receptors Inhibit High-Voltage–Activated Calcium Channels in Rat Sympathetic and Parasympathetic Neurons

2002 • 167 citations

Structural Features Important for .sigma.1 Receptor Binding

1994 • 129 citations

Endogenous ligands for sigma opioid receptors in the brain (“sigmaphin”): Evidence from binding assays

1986 • 117 citations

Endogenous psychoactive tryptamines reconsidered: an anxiolytic role for dimethyltryptamine

2005 • 115 citations

High affinity of sigma₁‐binding sites for sterol isomerization inhibitors: evidence for a pharmacological relationship with the yeast sterol C₈–C₇ isomerase

1997 • 110 citations

Membrane‐delimited coupling between sigma receptors and K⁺ channels in rat neurohypophysial terminals requires neither G‐protein nor ATP

2000 • 110 citations

N,N-Dimethyltryptamine: An Endogenous Hallucinogen

1981 • 106 citations

σ Receptor Activation Blocks Potassium Channels and Depresses Neuroexcitability in Rat Intracardiac Neurons

2005 • 83 citations

Tryptamine, N,N-Dimethyltryptamine, N,N-Dimethyl-5-hydroxytryptamine and 5-Methoxytryptamine in Human Blood and Urine

1965 • 83 citations

Identification of Regions of the σ-1 Receptor Ligand Binding Site Using a Novel Photoprobe

2007 • 82 citations

Characterization of the Cocaine Binding Site on the Sigma-1 Receptor

2007 • 71 citations

Sigma Receptor Photolabeling and Sigma Receptor-mediated Modulation of Potassium Channels in Tumor Cells

1999 • 68 citations

K⁺ channel modulation in rodent neurohypophysial nerve terminals by sigma receptors and not by dopamine receptors

1999 • 62 citations

Correlation between neuroleptic binding to σ1 and σ2 receptors and acute dystonic reactions

2000 • 53 citations

(125I)iodoazidococaine, a photoaffinity label for the haloperidol-sensitive sigma receptor.

1992 • 53 citations

BEHAVIOURAL CHANGES INDUCED BY N,N‐DIMETHYLTRYPTAMINE IN RODENTS

1980 • 35 citations

Inhibition of potassium currents by the sigma receptor ligand (+)-3-(3-hydroxyphenyl)-N-(1-propyl)piperidine in sympathetic neurons of the mouse isolated hypogastric ganglion

1990 • 31 citations

In Vivo Modulation of Sigma Receptor Sites by Calcitonin Gene‐related Peptide in the Mouse and Rat Hippocampal Formation: Radioligand Binding and Electrophysiological Studies

1995 • 17 citations

Ontogeny of N,N-Dimethyltryptamine and related indolealkylamine levels in neonatal rats

1984 • 15 citations