In Vivo Modulation of Sigma Receptor Sites by Calcitonin Gene‐related Peptide in the Mouse and Rat Hippocampal Formation: Radioligand Binding and Electrophysiological Studies

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products

1982 • 2,114 citations

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients.

1987 • 1,264 citations

WITHDRAWN: References

1982 • 822 citations

Sigma receptors: biology and function.

1990 • 799 citations

A proposal for the classification of sigma binding sites

1992 • 743 citations

ELECTROPHYSIOLOGY OF HIPPOCAMPAL NEURONS: II. AFTER-POTENTIALS AND REPETITIVE FIRING

1961 • 683 citations

Immunoreactive calcitonin gene-related peptide and substance P coexist in sensory neurons to the spinal cord and interact in spinal behavioral responses of the rat

1984 • 573 citations

Evidence for sigma opioid receptor: binding of [3H]SKF-10047 to etorphine-inaccessible sites in guinea-pig brain.

1982 • 409 citations

Autoradiographic localization of sigma receptor binding sites in guinea pig and rat central nervous system with (+)3H-3-(3-hydroxyphenyl)-N-(1- propyl)piperidine

1986 • 385 citations

Sigma opiates and certain antipsychotic drugs mutually inhibit (+)-[3H] SKF 10,047 and [3H]haloperidol binding in guinea pig brain membranes.

1984 • 348 citations

Pharmacological and autoradiographic discrimination of sigma and phencyclidine receptor binding sites in brain with (+)-[3H]SKF 10,047, (+)-[3H]-3-[3-hydroxyphenyl]-N-(1-propyl)piperidine and [3H]-1-[1-(2-thienyl)cyclohexyl]piperidine.

1986 • 339 citations

hCGRP8-37, a calcitonin gene-related peptide antagonist revealing calcitonin gene-related peptide receptor heterogeneity in brain and periphery.

1990 • 327 citations

Classification and nomenclature of phencyclidine and sigma receptor sites

1987 • 272 citations

Sigma and phencyclidine-like compounds as molecular probes in biology

1988 • 251 citations

Calcitonin gene-related peptide: Multiple actions, multiple receptors

1992 • 226 citations

Structure-activity profile of calcitonin gene-related peptide in peripheral and brain tissues. Evidence for receptor multiplicity.

1989 • 222 citations

Characterization of CGRP₁ and CGRP₂ Receptor Subtypesa

1992 • 185 citations

Autoradiographic visualization of haloperidol-sensitive sigma receptors in guinea-pig brain

1988 • 176 citations

In vivo electrophysiological evidence for a selective modulation of N-methyl-D-aspartate-induced neuronal activation in rat CA3 dorsal hippocampus by sigma ligands.

1992 • 173 citations

Calcitonin gene-related peptide in the nervous tissue

1989 • 164 citations

σ receptors

1991 • 148 citations

Receptor mechanisms in antipsychotic drug action: focus on sigma receptors

1989 • 138 citations

Endogenous ligands for sigma opioid receptors in the brain (“sigmaphin”): Evidence from binding assays

1986 • 117 citations

An endogenous ligand for the sigma opioid binding site

1987 • 102 citations

Sigma binding states in the brain; An emerging concept for multiple sites and their relevance for psychiatric disorders

1990 • 99 citations

Delineating biochemical and functional properties of sigma receptors: emerging concepts.

1993 • 99 citations

Autoradiographic distribution of non-dopaminergic binding sites labeled by [3H]haloperidol in rat brain

1987 • 92 citations

NMDA receptor related agents : biochemistry, pharmacology and behavior

1991 • 86 citations

The sigma receptor: a novel site implicated in psychosis and antipsychotic drug efficacy.

1988 • 83 citations

The Sigma Receptor

1988 • 76 citations

Autoradiographic distribution and receptor binding profile of [125I]Bolton Hunter-rat amylin binding sites in the rat brain.

1994 • 74 citations

The effects of sigma ligands and of neuropeptide Y on N‐methyl‐<scp>d</scp>‐aspartate‐induced neuronal activation of CA₃ dorsal hippocampus neurones are differentially affected by pertussin toxin

1994 • 65 citations

The novel anticonvulsant MK-801 interacts with central phencyclidine recognition sites in rat brain

1987 • 63 citations

Drugs Acting on σ and Phencyclidine Receptors

1989 • 61 citations

Neuropeptide Y potentiates the N-methyl-D-aspartate response in the CA3 dorsal hippocampus. II. Involvement of a subtype of sigma receptor.

1992 • 55 citations

Regulation of σ receptors and responsiveness to guanine nucleotides following repeated exposure of rats to haloperidol: further evidence for multiple σ binding sites

1991 • 50 citations

Evidence for in vivo interactions between neuropeptide Y-related peptides and sigma receptors in the mouse hippocampal formation

1993 • 45 citations

Neuropeptide Y potentiates selectively the N-methyl-D-aspartate response in the rat CA3 dorsal hippocampus. I. Involvement of an atypical neuropeptide Y receptor.

1992 • 44 citations

Current hypotheses on sigma receptors and their physiological role: possible implications in psychiatry.

1993 • 44 citations

Structure‐Activity Analysis of CGRP's Neurobehavioral Effectsa

1992 • 44 citations

Neuropeptide Y and peptide YY do not bind to brain σ and phencyclidine binding sites

1991 • 40 citations

Neuropeptide Y and JO 1784, a selective σ ligand, alter intestinal ion transport through a common, haloperidol-sensitive site

1990 • 30 citations

In vivo binding of [3H]d-N-allylnormetazocine and [3H]haloperidol to sigma receptors in the mouse brain.

1990 • 29 citations

Neurochemical Effects of CGRPa

1992 • 21 citations

Focal stimulation of specific pathways in the rat hippocampus causes a reduction in radioligand binding to the haloperidol-sensitive sigma receptor

1991 • 18 citations

Regulation of sigma activity by the amino-terminus of substance P in the mouse spinal cord: Involvement of phencyclidine (PCP) sites not linked to N-methyl-d-aspartate (NMDA) activity

1993 • 15 citations

Effect of guanine nucleotides and temperature on calcitonin gene-related peptide receptor binding sites in brain and peripheral tissues

1993 • 10 citations

In vivo interaction of neuropeptide Y and peptide YY with σ receptor sites in the mouse brain

1993 • 10 citations

Failure of σ-receptor ligands to reduce the excitatory actions of N-methyl-DL-aspartate on rat spinal neurons in-vivo

1990 • 9 citations